Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

Natalie L. Leong; Nima Kabir; Armin Arshi; Azadeh Nazemi; Ben M. Wu; David R. McAllister; Frank A. Petrigliano

doi:10.3791/52797

Journal

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생체공학

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엔지니어링 전방 십자 인대 이식의 평가 흉선 쥐 모델

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

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생체공학

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JoVE 신문 생체공학

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

엔지니어링 전방 십자 인대 이식의 평가 흉선 쥐 모델

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10,290 Views

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10:32 min

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March 26, 2015

DOI:

10.3791/52797-v

DOI:

10.3791/52797-v

•

10:32 min

March 26, 2015

•

9 Views

Natalie L. Leong¹, Nima Kabir¹, Armin Arshi¹, Azadeh Nazemi², Ben M. Wu², David R. McAllister¹, Frank A. Petrigliano¹

¹Department of Orthopaedic Surgery,University of California Los Angeles, ²Department of Bioengineering,University of California Los Angeles

Summary

Animal models are important tools for the evaluation of tissue-engineered grafts. This paper presents the protocol for preparing an electrospun biodegradable polymer graft for use in anterior cruciate ligament tissue engineering, as well as a surgical protocol for implantation in a rat model.