Microperfusion Technique to Investigate Regulation of Microvessel Permeability in Rat Mesentery

Fitz-Roy E. Curry; Joyce F. Clark; Roger H. Adamson

doi:10.3791/53210

Journal

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생물학

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Microperfusion 기술은 쥐 장간막에서 미세 혈관 투과성의 규정을 조사하기 위해

Microperfusion Technique to Investigate Regulation of Microvessel Permeability in Rat Mesentery

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JoVE 신문 생물학

Microperfusion Technique to Investigate Regulation of Microvessel Permeability in Rat Mesentery

Microperfusion 기술은 쥐 장간막에서 미세 혈관 투과성의 규정을 조사하기 위해

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9,679 Views

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12:48 min

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September 12, 2015

DOI:

10.3791/53210-v

DOI:

10.3791/53210-v

•

12:48 min

September 12, 2015

•

7 Views

Fitz-Roy E. Curry¹, Joyce F. Clark¹, Roger H. Adamson¹

¹Department of Physiology & Membrane Biology,University of California Davis

Summary

The modified Landis technique enables paired measurement of the hydraulic conductivity of individual microvessels in the mesentery of normal and genetically modified rats under control and test conditions using microperfusion techniques. It provides a convenient method to evaluate mechanisms that regulate microvessel permeability and transvascular exchange under physiological conditions.