Waiting
로그인 처리 중...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Neuroscience / A Protocol for Measuring Cue Reactivity in a Rat…
JoVE Journal
Neuroscience

JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.

JoVE Journal Neuroscience
A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
Postsynaptic Recordings at Afferent Dendrites Contacting Cochlear Inner Hair Cells: Monitoring Multivesicular Release at a Ribbon Synapse
Journal (Neuroscience)
Postsynaptic Recordings at Afferent Dendrites Contacting Cochlear Inner Hair Cells: Monitoring Multivesicular Release at a Ribbon Synapse
Assessment of Swim Endurance and Swim Behavior in Adult Zebrafish
Journal (Neuroscience)
Assessment of Swim Endurance and Swim Behavior in Adult Zebrafish
 

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder

Article DOI: 10.3791/55864-v • 07:51 min • June 18th, 2018
June 18th, 2018 •
*1,2,3, *1,4,5, 1,6, 1,6, 1,6, 1,6, 1,3,4
1Center for Addiction Research, University of Texas Medical Branch, 2Institute for Translational Sciences, University of Texas Medical Branch, 3Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, 4Department of Neurology, University of Texas Medical Branch, 5Department of Pathology, University of Texas Medical Branch, 6Department of Pharmacology and Toxicology, University of Texas Medical Branch
* These authors contributed equally

챕터

요약
Automatic Translation

Cue reactivity is conceptualized as sensitivity to cues linked with drug-taking experiences that contribute to craving and relapse in abstinent humans. Cue reactivity is modeled in rats by measuring attentional orientation toward drug-associated cues that results in appetitive approach behavior in a cue reactivity test following self-administration and forced abstinence.

Tags

Protocol Measuring Cue Reactivity Rat Model Cocaine Use Disorder Motivation Seek Cocaine Self-administration Relapse Risk Pre-clinical Pharmacotherapies Genetic Factors Environmental Factors Operant Task Drug-seeking Behavior Sprague Dawley Rats Acclimation Period Jugular Vein Catheters Saline Treatment Group Cocaine Treatment Group Training Program
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter