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Generation av High-Throughput tredimensionella tumör Spheroids för drogkontroll
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Generation av High-Throughput tredimensionella tumör Spheroids för drogkontroll

Article DOI: 10.3791/57476-v • 05:54 min • September 5th, 2018
September 5th, 2018 •
1, 1, 2, 2, 2, 2, 2, 1
1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research, 2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research

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Över en mängd olika tecken på sjukdom, mer fysiologiskt relevanta modeller är utvecklade och implementerade i drug discovery program. Ny modell systemet beskrivs här visar hur tredimensionella tumör spheroids kan vara odlade och screening i ett hög genomströmning 1536-well plate-baserat system att söka efter nya onkologi droger.

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Cancer Research fråga 139 tumör spheroids tredimensionella (3D) plattor med flera drug screening hög genomströmning definierade medium
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