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Developmental Biology

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Generatie van eerste hart veld-achtige cardiale progenitoren en ventriculaire-achtige Cardiomyocytes van menselijke pluripotente stamcellen

Article DOI: 10.3791/57688-v • 08:37 min • June 19th, 2018
June 19th, 2018 •
*1,2, *1, 1
1Sanford Burnham Prebys Medical Discovery Institute, 2Department of Bioengineering, University of California at San Diego
* These authors contributed equally

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Hier beschrijven we een schaalbare methode, met behulp van een eenvoudige combinatie van Activin A en lentivirus-gemedieerde Id1-overexpressie, voor het genereren van eerste hart veld-achtige cardiale progenitoren en ventriculaire-achtige cardiomyocytes van menselijke pluripotente stamcellen.

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Ontwikkelingsbiologie kwestie 136 Cardiac ziekte modellering stamcel gebaseerde therapieën eerste hart veld-achtige cardiale progenitorcellen ventriculaire-achtige cardiomyocytes Id1 hPSCs
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