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A Modified Surgical Model of Hind Limb Ischemia in ApoE-/- Mice using a Miniature Incision

Article DOI: 10.3791/62402-v • 05:47 min • May 13th, 2021
May 13th, 2021 •
1,2, 1,2, 3,4, 1, 1,2, 1,2
1Department of Surgery, Medical Faculty Manheim, Heidelberg University, 2European Center of Angioscience ECAS, Medical Faculty Manheim, Heidelberg University, 3Computer-Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, 4Cooperative Core Facility Animal Scanner ZI, Medical Faculty Mannheim, Heidelberg University

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요약
Automatic Translation

This article demonstrates an efficient surgical approach to establish acute ischemia in mice with a small incision. This approach can be applied by most research groups without any laboratory upgrades.

Tags

Modified Surgical Model Hind Limb Ischemia ApoE-/- Mice Miniature Incision Synovial Method Low Invasiveness Microsurgical Models Equipment And Tools Anesthesia Ointment Heating Pad Core Body Temperature Hair Removal Cream Hind Limb Skin Supine Position Dissecting Microscope Alcohol Disinfection Pointed Forceps Surgical Scissors Inguinal Region Subcutaneous Fat Tissue Proximal Femoral Neurovascular Bundle
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