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Delvis isjiasnerveligering
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Delvis isjiasnerveligering: En musemodell av kronisk nevropatisk smerte for å studere den antinociceptive effekten av nye terapier

Article DOI: 10.3791/64555-v • 08:16 min • October 6th, 2022
October 6th, 2022 •
1, 1, 2, 1, 1, 5, *1,2,3,4, *1,2
1Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, 2Department of Anesthesiology, College of Medicine, The University of Arizona, Tucson, 3Neuroscience Graduate Interdisciplinary Program, College of Medicine, The University of Arizona, Tucson, 4Comprehensive Pain and Addiction Center, The University of Arizona, Tucson, 5Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center
* These authors contributed equally

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Delvis isjiasnerveligering induserer langvarig kronisk nevropatisk smerte, preget av overdrevne responser på termiske og mekaniske stimuli. Denne musemodellen av nevropatisk smerte brukes ofte til å studere innovative terapier for smertebehandling. Denne artikkelen beskriver i detalj den kirurgiske prosedyren for å forbedre standardisering og reproduserbarhet.

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