Name: 쥐 발바닥 굴근에 대한 생체 내 정하중(등장성) 및 등속(등속성) 토크-속도-전력 프로파일의 구성 (동영상) | JoVE Journal
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Description: 학습하세요 쥐 발바닥 굴근의 생체 내 비침습적 토크-속도-전력 관계 측정법을 통해 근육 역학과 질병 영향을 연구하는 방법을. 이 프로토콜은 근육 기능 평가에 활용됩니다.

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<li>Andersen, L. L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Changes+in+the+human+muscle+force-velocity+relationship+in+response+to+resistance+training+and+subsequent+detraining%5BTitle%5D)+AND+%22J+Appl+Physiol%22%5BJournal%5D)">Changes in the human muscle force-velocity relationship in response to resistance training and subsequent detraining.</a> J Appl Physiol. 99 (1), 87-94 (2005).</li>
<li>Hinks, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Power+loss+is+attenuated+following+a+second+bout+of+high+intensity+eccentric+contractions+due+to+the+repeated+bout+effect%E2%80%99s+protection+of+rate+of+torque+and+velocity+development%5BTitle%5D)+AND+%22Appl+Physiol+Nutr+Metab%22%5BJournal%5D)">Power loss is attenuated following a second bout of high intensity eccentric contractions due to the repeated bout effect’s protection of rate of torque and velocity development.</a> Appl Physiol Nutr Metab. 46 (5), 461-472 (2020).</li>
<li>Dalton, B. H., Power, G. A., Paturel, J. R., Rice, C. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Older+men+are+more+fatigable+than+young+when+matched+for+maximal+power+and+knee+extension+angular+velocity+is+unconstrained%5BTitle%5D)+AND+%22Age%22%5BJournal%5D)">Older men are more fatigable than young when matched for maximal power and knee extension angular velocity is unconstrained.</a> Age. 37 (3), 49(2015).</li>
<li>Power, G. A., Dalton, B. H., Rice, C. L., Vandervoort, A. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Delayed+recovery+of+velocity-dependent+power+loss+following+eccentric+actions+of+the+ankle+dorsiflexors%5BTitle%5D)+AND+%22J+Appl+Physiol%22%5BJournal%5D)">Delayed recovery of velocity-dependent power loss following eccentric actions of the ankle dorsiflexors.</a> J Appl Physiol. 109 (3), 669-676 (2010).</li>
<li>Dalton, B. H., Allen, M. D., Power, G. A., Vandervoort, A. A., Rice, C. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+effect+of+knee+joint+angle+on+plantar+flexor+power+in+young+and+old+men%5BTitle%5D)+AND+%22Exp+Gerontol%22%5BJournal%5D)">The effect of knee joint angle on plantar flexor power in young and old men.</a> Exp Gerontol. 52, 70-76 (2014).</li>
<li>Power, G. A., Dalton, B. H., Rice, C. L., Vandervoort, A. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Peak+power+is+reduced+following+lengthening+contractions+despite+a+maintenance+of+shortening+velocity%5BTitle%5D)+AND+%22Appl+Physiol+Nutr+Metab%22%5BJournal%5D)">Peak power is reduced following lengthening contractions despite a maintenance of shortening velocity.</a> Appl Physiol Nutr Metab. 38 (12), 1196-1205 (2013).</li>
<li>McNeil, C. J., Rice, C. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Fatigability+is+increased+with+age+during+velocity-dependent+contractions+of+the+dorsiflexors%5BTitle%5D)+AND+%22J+Gerontol+A+Biol+Sci+Med+Sci%22%5BJournal%5D)">Fatigability is increased with age during velocity-dependent contractions of the dorsiflexors.</a> J Gerontol A Biol Sci Med Sci. 62 (6), 624-629 (2007).</li>
<li>Knight, K. L., Ingersoll, C. D., Bartholomew, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Isotonic+contractions+might+be+more+effective+than+isokinetic+contractions+in+developing+muscle+strength%5BTitle%5D)+AND+%22J+Sport+Rehabil%22%5BJournal%5D)">Isotonic contractions might be more effective than isokinetic contractions in developing muscle strength.</a> J Sport Rehabil. 10 (2), 124-131 (2001).</li>
<li>Thompson, B. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((It%E2%80%99s+time+to+re-evaluate+the+reporting+of+common+measures+from+isokinetic+dynamometers%3A+isokinetic+for+torque%2C+isotonic+for+power%5BTitle%5D)+AND+%22Front+Sports+Act+Living%22%5BJournal%5D)">It’s time to re-evaluate the reporting of common measures from isokinetic dynamometers: isokinetic for torque, isotonic for power.</a> Front Sports Act Living. 7, 1472712(2025).</li>
<li>Leeuwenburgh, C., Gurley, C. M., Strotman, B. A., Dupont-Versteegden, E. E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Age-related+differences+in+apoptosis+with+disuse+atrophy+in+soleus+muscle%5BTitle%5D)+AND+%22Am+J+Physiol+Regul+Integr+Comp+Physiol%22%5BJournal%5D)">Age-related differences in apoptosis with disuse atrophy in soleus muscle.</a> Am J Physiol Regul Integr Comp Physiol. 288 (5), R1288-R1296 (2005).</li>
<li>Padilla, C. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Profiling+age-related+muscle+weakness+and+wasting%3A+neuromuscular+junction+transmission+as+a+driver+of+age-related+physical+decline%5BTitle%5D)+AND+%22Geroscience%22%5BJournal%5D)">Profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline.</a> Geroscience. 43 (3), 1265-1281 (2021).</li>
<li>Fuqua, J. D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Impaired+proteostatic+mechanisms+other+than+decreased+protein+synthesis+limit+old+skeletal+muscle+recovery+after+disuse+atrophy%5BTitle%5D)+AND+%22J+Cachexia+Sarcopenia+Muscle%22%5BJournal%5D)">Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy.</a> J Cachexia Sarcopenia Muscle. 14 (5), 2076-2089 (2023).</li>
<li>Ochi, E., Nakazato, K., Ishii, N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effects+of+eccentric+exercise+on+joint+stiffness+and+muscle+connectin+%28titin%29+isoform+in+the+rat+hindlimb%5BTitle%5D)+AND+%22J+Physiol+Sci%22%5BJournal%5D)">Effects of eccentric exercise on joint stiffness and muscle connectin (titin) isoform in the rat hindlimb.</a> J Physiol Sci. 57 (1), 1-6 (2007).</li>
<li>Warren, G. L., Stallone, J. L., Allen, M. R., Bloomfield, S. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Functional+recovery+of+the+plantarflexor+muscle+group+after+hindlimb+unloading+in+the+rat%5BTitle%5D)+AND+%22Eur+J+Appl+Physiol%22%5BJournal%5D)">Functional recovery of the plantarflexor muscle group after hindlimb unloading in the rat.</a> Eur J Appl Physiol. 93 (1-2), 130-138 (2004).</li>
<li>Herzog, W., Leonard, T. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Force+enhancement+following+stretching+of+skeletal+muscle%3A+a+new+mechanism%5BTitle%5D)+AND+%22J+Exp+Biol%22%5BJournal%5D)">Force enhancement following stretching of skeletal muscle: a new mechanism.</a> J Exp Biol. 205 (Pt 9), 1275-1283 (2002).</li>
<li>Lewis, M. T., Kasper, J. D., Bazil, J. N., Frisbee, J. C., Wiseman, R. W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Skeletal+muscle+energetics+are+compromised+only+during+high-intensity+contractions+in+the+Goto-Kakizaki+rat+model+of+type+2+diabetes%5BTitle%5D)+AND+%22Am+J+Physiol+Regul+Integr+Comp+Physiol%22%5BJournal%5D)">Skeletal muscle energetics are compromised only during high-intensity contractions in the Goto-Kakizaki rat model of type 2 diabetes.</a> Am J Physiol Regul Integr Comp Physiol. 317 (2), R356-R368 (2019).</li>
<li>Hill, C., James, R., Cox, V., Tallis, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Does+dietary-induced+obesity+in+old+age+impair+the+contractile+performance+of+isolated+mouse+soleus%2C+extensor+digitorum+longus+and+diaphragm+skeletal+muscles%5BTitle%5D)+AND+%22Nutrients%22%5BJournal%5D)">Does dietary-induced obesity in old age impair the contractile performance of isolated mouse soleus, extensor digitorum longus and diaphragm skeletal muscles.</a> Nutrients. 11 (3), 505(2019).</li>
<li>Yuan, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+atypical+%CE%B2-blocker+S-oxprenolol+reduces+cachexia+and+improves+survival+in+a+rat+cancer+cachexia+model%5BTitle%5D)+AND+%22J+Cachexia+Sarcopenia+Muscle%22%5BJournal%5D)">The atypical β-blocker S-oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model.</a> J Cachexia Sarcopenia Muscle. 14 (1), 653-660 (2023).</li>
<li>Hinks, A., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Age-related+differences+in+the+loss+and+recovery+of+serial+sarcomere+number+following+disuse+atrophy+in+rats%5BTitle%5D)+AND+%22Skeletal+Muscle%22%5BJournal%5D)">Age-related differences in the loss and recovery of serial sarcomere number following disuse atrophy in rats.</a> Skeletal Muscle. 14 (1), 18(2024).</li>
<li>Hulst, J. B., Minamoto, V. B., Lim, M. B., Bremner, S. N., Ward, S. R., Lieber, R. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Systematic+test+of+neurotoxin+dose+and+volume+on+muscle+function+in+a+rat+model%5BTitle%5D)+AND+%22Muscle+Nerve%22%5BJournal%5D)">Systematic test of neurotoxin dose and volume on muscle function in a rat model.</a> Muscle Nerve. 49 (5), 709-715 (2014).</li>
<li>Wang, X., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Human+neural+stem+cells+transplanted+during+the+sequelae+phase+alleviate+motor+deficits+in+a+rat+model+of+cerebral+palsy%5BTitle%5D)+AND+%22Cytotherapy%22%5BJournal%5D)">Human neural stem cells transplanted during the sequelae phase alleviate motor deficits in a rat model of cerebral palsy.</a> Cytotherapy. 26 (12), 1491-1504 (2024).</li>
<li>Baltgalvis, K. A., Call, J. A., Cochrane, G. D., Laker, R. C., Yan, Z., Lowe, D. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Exercise+training+improves+plantar+flexor+muscle+function+in+mdx+mice%5BTitle%5D)+AND+%22Med+Sci+Sports+Exerc%22%5BJournal%5D)">Exercise training improves plantar flexor muscle function in mdx mice.</a> Med Sci Sports Exerc. 44 (9), 1671-1679 (2012).</li>
<li>Sam, M., Shah, S., Fridén, J., Milner, D. J., Capetanaki, Y., Lieber, R. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Desmin+knockout+muscles+generate+lower+stress+and+are+less+vulnerable+to+injury+compared+with+wild-type+muscles%5BTitle%5D)+AND+%22Am+J+Physiol+Cell+Physiol%22%5BJournal%5D)">Desmin knockout muscles generate lower stress and are less vulnerable to injury compared with wild-type muscles.</a> Am J Physiol Cell Physiol. 279 (4), C1116-C1122 (2000).</li>
<li>Mintz, E. L., Passipieri, J. A., Lovell, D. Y., Christ, G. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Applications+of+in+vivo+functional+testing+of+the+rat+tibialis+anterior+for+evaluating+tissue+engineered+skeletal+muscle+repair%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Applications of in vivo functional testing of the rat tibialis anterior for evaluating tissue engineered skeletal muscle repair.</a> J Vis Exp. (116), e54487(2016).</li>
<li>Song, H., Nakazato, K., Nakajima, H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effect+of+increased+excursion+of+the+ankle+on+the+severity+of+acute+eccentric+contraction-induced+strain+injury+in+the+gastrocnemius%3A+an+in+vivo+rat+study%5BTitle%5D)+AND+%22Am+J+Sports+Med%22%5BJournal%5D)">Effect of increased excursion of the ankle on the severity of acute eccentric contraction-induced strain injury in the gastrocnemius: an in vivo rat study.</a> Am J Sports Med. 32 (5), 1263-1269 (2004).</li>
<li>Hinks, A., Patterson, M. A., Njai, B. S., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Age-related+blunting+of+serial+sarcomerogenesis+and+mechanical+adaptations+following+4+weeks+of+maximal+eccentric+resistance+training%5BTitle%5D)+AND+%22J+Appl+Physiol%22%5BJournal%5D)">Age-related blunting of serial sarcomerogenesis and mechanical adaptations following 4 weeks of maximal eccentric resistance training.</a> J Appl Physiol. 136 (5), 1209-1225 (2024).</li>
<li>Hinks, A. A., Vlemmix, E., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Submaximal+eccentric+resistance+training+increases+serial+sarcomere+number+and+improves+dynamic+muscle+performance+in+old+rats%5BTitle%5D)+AND+%22Physiol+Rep%22%5BJournal%5D)">Submaximal eccentric resistance training increases serial sarcomere number and improves dynamic muscle performance in old rats.</a> Physiol Rep. 12 (19), e70036(2024).</li>
<li>Hinks, A., Vlemmix, E., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Submaximal+eccentric+training+during+immobilization+does+not+prevent+serial+sarcomere+loss+or+impairments+in+mechanical+function+in+old+or+young+rats%5BTitle%5D)+AND+%22J+Gerontol+A+Biol+Sci+Med+Sci%22%5BJournal%5D)">Submaximal eccentric training during immobilization does not prevent serial sarcomere loss or impairments in mechanical function in old or young rats.</a> J Gerontol A Biol Sci Med Sci. 80 (7), glaf082(2025).</li>
<li>Vlemmix, E., Hinks, A., Power, G. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Serial+sarcomerogenesis+does+not+contribute+to+the+initial+repeated+bout+effect+in+skeletal+muscle%5BTitle%5D)+AND+%22J+Biomech%22%5BJournal%5D)">Serial sarcomerogenesis does not contribute to the initial repeated bout effect in skeletal muscle.</a> J Biomech. 187, 112767(2025).</li>
<li>Oh, S. S., Narver, H. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mouse+and+rat+anesthesia+and+analgesia%5BTitle%5D)+AND+%22Curr+Protoc%22%5BJournal%5D)">Mouse and rat anesthesia and analgesia.</a> Curr Protoc. 4 (2), e995(2024).</li>
<li>Paris, M. T., McNeil, C. J., Power, G. A., Rice, C. L., Dalton, B. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Age-related+performance+fatigability%3A+a+comprehensive+review+of+dynamic+tasks%5BTitle%5D)+AND+%22J+Appl+Physiol%22%5BJournal%5D)">Age-related performance fatigability: a comprehensive review of dynamic tasks.</a> J Appl Physiol. 133 (4), 850-866 (2022).</li>
<li>Hinks, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Time+course+changes+in+in+vivo+muscle+mechanical+function+and+Ca2%2B+regulation+of+force+following+experimentally+induced+gradual+ovarian+failure+in+mice%5BTitle%5D)+AND+%22Exp+Physiol%22%5BJournal%5D)">Time course changes in in vivo muscle mechanical function and Ca2+ regulation of force following experimentally induced gradual ovarian failure in mice.</a> Exp Physiol. 109 (5), 711-728 (2024).</li>
<li>Edman, K. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Double-hyperbolic+force-velocity+relation+in+frog+muscle+fibres%5BTitle%5D)+AND+%22J+Physiol%22%5BJournal%5D)">Double-hyperbolic force-velocity relation in frog muscle fibres.</a> J Physiol. 404 (1), 301-321 (1988).</li>
</ol>

<table><tbody><tr><td>1-1/2" 강철 아연도금 매끄러운 마감 못 및 nbsp;</td><td>힐먼 그룹 캐나다 ULC, 피커링, 온타리오, 캐나다</td><td>https://shop.hillmangroup.ca/ccrz__ProductDetails?sku=461146&cclcl=en_US</td><td>맞춤형 전극 홀더에 대해(제작 지침은 보충 그림 1에 제공됨)</td></tr><tr><td>쥐 장치</td><td>오로라 사이언티픽 주식회사 (오로라, 온타리오, 캐나다)</td><td>806D&nbsp;</td><td></td></tr><tr><td>Tinkercad(오픈 소스 소프트웨어)로 설계되고 3D 프린팅된 맞춤형 전극 고정 부착물</td><td>오토데스크 팅커캐드&nbsp;</td><td>www.tinkercad.com</td><td>맞춤형 전극 홀더에 대해(제작 지침은 보충 그림 1에 제공됨)</td></tr><tr><td>고출력 이상 자극기</td><td>오로라 사이언티픽 주식회사 (오로라, 온타리오, 캐나다)</td><td>701C</td><td></td></tr><tr><td>레고 부품</td><td>BrickLink.com</td><td>모든 LEGO 및 레지그의 BrickLink.com 코드는 보충 그림 S1을 참조하십시오; 부품</td><td>맞춤형 전극 홀더에 대해(제작 지침은 보충 그림 1에 제공됨)</td></tr><tr><td>스펙트라 360 전극 젤</td><td>스펙트라</td><td>https://www.orthocanada.com/en/spectra-electrode-gel?utm_term=&utm_campaign=Canada+EN+-+Search+-+OrthoCanada&utm_source=adwords&utm_medium=ppc&hsa_acc=1971735470&hsa_cam=136169080&hsa_grp=139530010212&hsa_ad=586754644289&hsa_src=g&hsa_tgt=dsa-19959388920&hsa_kw=&hsa_mt=&hsa_net=adwords&hsa_ver=3&gad_source=1&gad_campaignid=136169080&gbraid=0AAAAAD1V26BmzV4eR9tkH_8Truu4W7uu6&gclid=Cj0KCQjwnJfEBhCzARIsAIMtfKLpFSpoPZdXDBtyR8sRgHYCfYuELZFPs4g8U6r8t4_chBuz5KF0pBIaAoQ3EALw_wcB</td><td></td></tr><tr><td>시스테인 야간 윤활제 안과 연고</td><td>시스테인</td><td>https://www.amazon.ca/dp/B004RSQGWC?ref=nb_sb_ss_w_as-reorder_k0_1_12&amp=&crid=38CVEZ82H7F4&amp=&sprefix=eye+ointment</td><td></td></tr><tr><td>스프래그-도울리 쥐 10마리의 암컷</td><td>찰스 리버 연구소 (캐나다 퀘벡주 세네빌)</td><td>변종 코드: 001</td><td></td></tr><tr><td>트랜스포어 수술용 테이프</td><td>3M (캐나다 온타리오주 밀턴)</td><td>1527</td><td></td></tr><tr><td>Veet 퓨어 제모 크림</td><td>베트</td><td>https://www.walmart.ca/en/ip/Veet-Pure-Hair-Removal-Cream-Legs-Body-Sensitive-Skin-400-mL/10032637</td><td></td></tr><tr><td>온수기/순환기</td><td>오로라 사이언티픽 주식회사 (오로라, 온타리오, 캐나다)</td><td>827A&nbsp;</td><td></td></tr></tbody></table>

쥐 발바닥 굴근에 대한 생체 내 정하중(등장성) 및 등속(등속성) 토크-속도-전력 프로파일의 구성

Construction of Constant-Load (Isotonic) and Constant-Velocity (Isokinetic) Torque-Velocity-Power Profiles In vivo for the Rat Plantar Flexors

Understanding the torque-velocity-power relationship of muscle is critical for assessing dynamic muscle performance, which has implications for health and ...

construction-constant-load-isotonic-constant-velocity-isokinetic

Research

연구

JoVE Journal

Bioengineering

생명공학

우리는 송곳니 hindlimb의 근육 강도와 반복 편심 수축으로 근육 응답을 측정하기 위해 최소한 - 침략과 고통없이 방법을 설명합니다.

VIVO 개 근육 기능 분석에

생체내에</em수축 유도 부상 및 복구의 비침습 모니터링> 쥐 모델

이 동영상은 수술 준비와 쥐 안쪽 gastrocnemius 근육 준비의 수축 반응을 연구하는 데 필요한 절차를...

쥐 절차<em&gt; 현장에서</em&gt; 골격근 수축 등록

신경근 기능의 변화를 평가하기 위한 프로토콜을 제시합니다. 경피적 전기 신경 자극은 근육 반응을 유발하는 비침습적 방법입니다. 이러한 반응의 전기생리학적, 기계적 특성을 통해 뇌에서 근육(척추상, 척추 및 말초 수준)에 이르는 신경근 기능을 평가할 수 있습니다.

경피적 전기 신경 자극을 사용하여 신경 근육 기능의 평가

우리는 비골 신경의 자극과 쥐 뒷다리의 앞쪽 가랑이 구획의 수축에 따라 발의 배측 굴곡을 측정하기 위한 생체 내 프로토콜을 설명합니다. 이러한 측정은 근육 복구 및 재생에 대한 골격근 병리학 및 조직 공학 접근 방식을 평가하는 데 필수적인 번역 도구입니다.

의 응용 프로그램<em&gt; 생체</em&gt; 조직 평가를위한 쥐 앞정 전방의 기능 테스트는 골격근 수리 엔지니어링

모터 회복의 평가는 실험적인 말초 신경 연구에서 벤치마크 결과 측정으로 남아 있습니다. 쥐의 티볼리스 전방 근육의 동면 파탄력 측정은 경련성 신경 결함의 재구성 후 기능적 결과를 평가하는 귀중한 도구입니다. 방법과 뉘앙스는이 문서에 자세히 설명되어 있습니다.

쥐의 티비아리스 전방 근육의 최대 동면 성 파타닉 힘 측정

무릎 근간근의 정량화는 노화, 질병, 부상 및 재활에 대한 기능적 적응을 이해하는 것이 필수적입니다. 생체 무릎 확장 이소메트릭 피크 파타닉 토크에서 반복적으로 측정하는 새로운 방법을 제시합니다.

마우스에서 무릎 엑스텐서 근육 기능의 생체 측정

본 프로토콜은 마취된 돼지에서 일반적인 비골 신경의 전기 자극을 통해 얻어진 생체내 토크 데이터의 평가 및 해석에 대한 간결한 실험 세부사항을 기술한다.

생체 내 돼지의 Hindlimb Dorsiflexor 등각 토크 측정

이 기사는 실험실 설치류의 "아바타" 근육을 사용하여 근력 반응에 대한 긴장 과도 및 활성화의 기여도를 평가하기 위해 생체 외 작업 루프 실험 중 생체 내 근육 힘 생성을 에뮬레이트하는 방법론에 대해 자세히 설명합니다.

"Avatar", In vivo 변형 및 활성화를 사용한 변형된 Ex vivo Work Loop 실험

이 프로토콜은 남용 유발 건병증의 생체 내 모델에 대해 쥐 아킬레스건에서 정량화 가능하고 통제된 피로 부상을 유도하는 데 사용되는 테스트 시스템을 제시합니다. 이 절차는 쥐의 발목을 관절 액추에이터에 고정하는 것으로 구성되며, 이 액추에이터는 맞춤형으로 작성된 MATLAB 스크립트로 수동 발목 배측굴곡을 수행합니다.

과사용 유발 건병증의 In Vivo 모델을 위한 수동 발목 배굴곡 검사 시스템

학습하세요 쥐 발바닥 굴근의 생체 내 비침습적 토크-속도-전력 관계 측정법을 통해 근육 역학과 질병 영향을 연구하는 방법을. 이 프로토콜은 근육 기능 평가에 활용됩니다.

쥐 발바닥 굴근에 대한 생체 내 정하중(등장성) 및 등속(등속성) 토크-속도-전력 프로파일의 구성

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