Morphogenesis is a complex event that establishes the correct tissue architecture. It is crucial for the specific functions of developed tissues. Investigations of spatiotemporal changes in intra- and extracellular activities have provided key clues fora comprehensive understanding of the principles of the morphogenic process. To monitor these activities, visualization methods that use current optical technologies have been extremely useful to expand our knowledge in the field of developmental biology. To achieve the successful execution of these techniques, integrated optical and biological expertise is required. In addition to the selection of the appropriate optical tools (e.g., type of microscope), it is also critical to design an adequate optical readout that reflects the biological activity of the imaging targets.
This collection session welcomes state-of-the-art, creative technologies to visualize biophysical as well as biochemical dynamics during morphogenesis. The imaging targets include various developing biological systems, including those at the subcellular, tissue, and whole-organ scale. Examples of methods that may be included in this collection are: original imaging processes designed for specific tissues or organs, improvements in or novel designs of biosensors and chemical dyes, optical technologies (e.g., enhanced spatiotemporal resolution), improved culture conditions for visualization (e.g., increasing cell permeability), and intravital imaging techniques.