Spin-Spin-koppeling: koppeling met twee bindingen (geminale koppeling)

Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling.

Examples include the coupling between diastereotopic protons in chiral molecules and unsymmetrical alkenes.

The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms.

However, spin information is transmitted less effectively, and ²J values are usually weaker than ¹J values.

The energy of configurations with parallel spins is often lowered, resulting in negative ²J values, though the sign of J is not evident from the spectrum.

²J values become more positive as the s character increases, which is observed as a decrease in the magnitude of J in the spectrum.

In cycloalkanes, as the H–C–H angle approaches 109 degrees, the ²J values become more negative, which is observed as an increase in the extent of coupling.

An electronegative substituent α to the coupled nuclei makes the ²J values more positive, as seen in iodomethane and formaldehyde.