Bloed- en zenuwvoorziening naar de botten

Bones have an extensive blood and nerve supply that helps in remodeling, repair, and mineral homeostasis.

In a typical long bone, the nutrient artery enters the diaphysis via the nutrient foramen. It then divides into ascending and descending branches that run parallel to the diaphysis.

These vessels further branch radially to supply blood to the bone marrow and the inner compact bone.

At the metaphyses, these arteries branch profusely, forming a network that connects with the metaphyseal arteries. As a result, metaphyses are the most vascular parts of the bone.

The epiphyses have another set of vessels— the epiphyseal arteries, that branch out to supply the spongy bone.

Additionally, bone also has many periosteal arteries that enter via Volkmann's canals to supply the outer compact bone.

The deoxygenated blood drains out through veins that mirror the arterial paths, the major ones being the periosteal, nutrient, metaphyseal, and epiphyseal veins.

The vascular path is also shared by sensory nerves that innervate the bones. These sensory nerves can detect pain signals, making bone damage, such as fractures, very painful.