Aggregate Particles
Aggregate Particles - Related Videos
02:14
Tracking Aggregation of Virus-Like Particles Using Dynamic Light Scattering
0 Views •
2026
Source: Moore, M. D., et al. Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity. J. Vis. Exp. (2017)The video demonstrates a protocol for monitoring the heat-induced aggregation of virus-like particles using dynamic light scattering (DLS). It begins with preparing a monodisperse suspension of purified particles. The sample is then loaded into a preheated DLS instrument. As the capsid proteins denature with heat, exposed hydrophobic regions cause particle...
10:10
Aggregates for Concrete and Asphaltic Mixes
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2023
Source: Roberto Leon, Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA Concrete and asphalt are by far the most common construction materials used today. Concrete is a composite material consisting of cement, water, air, coarse aggregate, and fine aggregates. Fine aggregates are typically sands and coarse aggregates are natural or crushed rocks. Chemical admixtures to modify certain specific properties are also commonly used (i.e., superplasticizers to make the...
02:41
Concentration and Purification of Viral Particles
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2026
Source: Fricano-Kugler, C. J., et al. Designing, Packaging, and Delivery of High Titer CRISPR Retro and Lentiviruses via Stereotaxic Injection. J. Vis. Exp. (2016).This video demonstrates the step-by-step process for concentrating and purifying lentiviral particles from a mixed suspension containing host cell debris. The procedure utilizes centrifugation, filtration, and PEG-salt precipitation to isolate viral particles while removing soluble impurities. The final product is resuspended in a...
03:37
Subatomic Particles
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2020
Dalton was only partially correct about the particles that make up matter. All matter is composed of atoms, and atoms are composed of three smaller subatomic particles: protons, neutrons, and electrons. These three particles account for the mass and the charge of an atom. The Discovery of the Electron The first clue about the subatomic structure came at the end of the 19th century when J.J. Thomson discovered the electron using a cathode ray tube. This apparatus consisted of a sealed glass...
09:44
Laboratory Drop Towers for the Experimental Simulation of Dust-aggregate Collisions in the Early Solar System
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Cited by 11 •
2014
We present a technique to achieve low-velocity to intermediate-velocity collisions between fragile dust aggregates in the laboratory. For this purpose, two vacuum drop-tower setups have been developed that allow collision velocities between <0.01 and ~10 m/sec. The collision events are recorded by high-speed imaging.
FAQs
Aggregation becomes favorable when attractive interactions between neighboring particles exceed the forces separating them. Van der Waals attraction, electrostatic interactions, liquid bridges, and chemical bonding can each contribute to cohesion. The resulting balance determines whether particles remain discrete or develop a larger structure, which directly affects the stability and mechanical behavior of the particulate material.
Mixing, shear, and fluid flow can disrupt aggregates by applying forces that overcome interparticle cohesion. Stronger disruptive conditions may break apart weak structures, whereas cohesive bonds can preserve more resistant aggregates. Engineers must therefore consider both the forces that create aggregation and the processing conditions that may reduce aggregate size or alter material stability.
Size, shape, porosity, and mechanical strength govern how aggregates behave during processing and use. These properties influence flowability, packing, dissolution, filtration, and reaction rates in different ways. For example, changes in porosity or structure can alter how readily fluids interact with the material, while size and shape affect packing and movement through an engineering system.
Liquid bridges and chemical bonding provide cohesive connections that can make aggregates more resistant to disruption. Their presence changes the mechanical strength and stability of the assembled structure compared with interactions based only on weaker attractions. Recognizing the bonding mechanism helps engineers interpret why particulate materials behave differently during mixing, transport, processing, or storage.
Engineers should evaluate aggregate size, shape, porosity, and mechanical strength alongside the intended operation. These characteristics help predict flowability, packing, dissolution, filtration, and reaction behavior. Evaluating them during design supports selection of suitable material structures and processing conditions, improving product performance, process efficiency, and stability in systems that handle particulate materials.
Their behavior matters in powders, granules, slurries, catalysts, ceramics, pharmaceuticals, and construction materials. In each case, aggregation can influence how the material flows, packs, dissolves, filters, or reacts. Engineering control of aggregate structure therefore supports different goals, including reliable handling, efficient processing, material stability, and performance tailored to the application.