Monopolar Electrical Knife

A monopolar electrical knife is an electrosurgical instrument that uses high-frequency electrical energy to cut tissue or control bleeding during surgical procedures. Its active electrode delivers alternating current through the target tissue, while a separate return electrode, typically a dispersive pad, completes the circuit; tissue resistance converts the energy into heat, producing cutting or coagulation depending on waveform, power, and tissue contact. This technique can reduce mechanical trauma and support hemostasis in open and minimally invasive surgery, but safe use requires appropriate electrode placement, controlled energy delivery, and attention to thermal injury and electrical safety.

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Research

JoVE Journal - Bioengineering
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Specimen Preparation, Imaging, and Analysis Protocols for Knife-edge Scanning Microscopy

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Cited by 15 •

2011

The full process from brain specimen preparation to serial sectioning imaging using the Knife-Edge Scanning Microscope, to data visualization and analysis is described. This technique is currently used to acquire mouse brain data, but it is applicable to other organs, other species.

Education

JoVE Science Education - Physics
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Electric Potential

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2023

Source: Yong P. Chen, PhD, Department of Physics & Astronomy, College of Science, Purdue University, West Lafayette, IN Electric potential, also known as "voltage", measures the electric potential energy per unit charge. Electric field is a scalar quantity and is fundamental to many electrical effects. Like potential energy, what is physically meaningful is the difference in the electric potential. For example, the spatial variation in the electric potential is related to the electric...

Education

JoVE Science Education - Basic Biology

Electrical Safety

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2023

Robert M. Rioux & Suprita Jharimune, Pennsylvania State University, University Park, PA Among the many hazards present in the laboratory, electrical hazards are one of the most common we must be cognizant of since most of the laboratory equipment we use requires electricity for operation. Improper handling or operation of electrical devices might lead to electric shock with the potential risk of injury or even death. Electric sparks can lead to fire or explosion (since many flammable...

Electric Fields

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2023

Source: Yong P. Chen, PhD, Department of Physics & Astronomy, College of Science, Purdue University, West Lafayette, IN An electric field is generated by a charged object (referred to as the source charge) in the space around it, and represents the ability to exert electric force on another charged object (referred to as the test charge). Represented by a vector at any given point in the space, the electric field is the electrical force per unit test charge placed at that point (the force...

Changing the Direction and Orientation of Electric Field During Electric Pulses Application Improves Plasmid Gene Transfer in vitro

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Cited by 2 •

2011

Gene transfection by electroporation is improved approximately two times when orientation of electric field is changed during pulse application, while cell viability is not affected. The increase in gene transfection is caused by the increase of the membrane area which is made competent for DNA entry into the cell.

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