Outpatient Phototherapy

Outpatient phototherapy is a treatment that uses prescribed doses of light, usually ultraviolet A (UVA) or narrowband ultraviolet B (UVB), in a clinic or supervised home setting to manage skin disease without hospital admission. During treatment, controlled ultraviolet exposure alters local immune activity, reduces inflammation, and can slow excessive keratinocyte proliferation; UVA may be combined with a photosensitizing agent such as psoralen. It is used in medicine for conditions including psoriasis, vitiligo, atopic dermatitis, and cutaneous T-cell lymphoma. Treatment schedules, dose escalation, eye protection, and skin monitoring help balance therapeutic benefit with risks such as erythema and cumulative photodamage.

Outpatient Phototherapy - Related Videos

Research

JoVE Journal - Medicine
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Conducting Respiratory Oscillometry in an Outpatient Setting

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Cited by 6 •

2022

We demonstrate a standard operating protocol to conduct respiratory oscillometry, highlighting key quality control and assurance procedures.

Research

JoVE Journal - Immunology and Infection

Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth

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Cited by 5 •

2019

Here, we present a protocol to assess the outcome of red light application on the growth of Candida albicans biofilm. A non-coherent red light device with the wavelength of 635 nm and energy density of 87.6 J·cm-2 was applied throughout the growth of Candida albicans biofilms for 48 h.

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

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Cited by 26 •

2013

Psoriasis is a chronic, immune-mediated inflammatory skin disease. The Goeckerman regimen, formulated for the treatment of psoriasis, consists of exposure to ultraviolet B (UVB) light and application of crude coal tar (CCT). The following protocol is for the administration of Goeckerman therapy for the treatment of moderate-to-severe psoriasis.

Research

JoVE Journal - Medicine
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Application of Lucilia sericata Larvae in Debridement of Pressure Wounds in Outpatient Settings

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Cited by 4 •

2021

Maggots of Lucilia sericata were used in the debridement of deep pressure sores in outpatient settings for the treatment of pressure sores involving the complete skin thickness. The technique presented in the article does not pose risks for the patient.

A Near-Infrared Photoimmunotherapy Technique to Treat Lung Cancer in a Murine Model

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2025

This video demonstrates a near-infrared photoimmunotherapy technique to treat lung cancer in an engineered mouse model exhibiting luciferase-expressing tumor cells. Upon injecting an antibody-photosensitizer conjugate (APC) that binds to specific antigens on the tumor cells, the mouse is exposed to near-infrared radiation, inducing photochemical changes in the APC and leading to necrotic death of the bound tumor cells. The effectiveness of the treatment is monitored by injecting luciferin, a...

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