Water Tank Test

The Water Tank Test is a behavioral neuroscience assay used to assess spatial learning, memory, and navigation in rodents by measuring how they locate an escape platform in a pool. During training, an animal swims in a circular tank containing a submerged platform, using visual and spatial cues to learn its location; escape latency and path length typically track acquisition, while a probe trial without the platform tests memory for the learned location. Researchers use this paradigm to study hippocampal function and detect cognitive changes associated with brain injury, neurological disease, aging, or experimental treatments, while accounting for swimming ability and motivation.

Water Tank Test - Related Videos

Research

JoVE EoE - Danio rerio (zebrafish)

Novel Tank Diving Assay: A Method to Study Innate Stress Responses in Zebrafish

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2023

The article describes a behavioral method to assess stress in zebrafish. In response to stress, zebrafish tends to swim at bottom of a tank until stress is removed. The sample protocol describes stepwise method for performing the assay.

Do-It-Yourself Device for Recovery of Cryopreserved Samples Accidentally Dropped into Cryogenic Storage Tanks

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Cited by 5 •

2012

Here we present a low cost, durable cryotolerant device for sample retrieval from Dewar tanks filled with liquid nitrogen. The ease of construction and modular design of the device makes the process of sample retrieval from cryogenic tanks safe and easy.

Research

JoVE Journal - Neuroscience

Neurotoxicity Assessment in Adult Danio rerio using a Battery of Behavioral Tests in a Single Tank

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Cited by 2 •

2023

Here, we present a comprehensive behavioral test battery, including the novel tank, Shoaling, and social preference tests, to effectively determine the potential neurotoxic effects of chemicals (e.g., methamphetamine and glyphosate) on adult zebrafish using a single tank. This method is relevant to neurotoxicity and environmental research.

Capturing Flow-weighted Water and Suspended Particulates from Agricultural Canals During Drainage Events

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Cited by 2 •

2017

Nutrients present in particulate form can contribute significantly to the overall loads in agricultural drainage waters. This study describes a novel method to capture flow-weighted water and suspended particulates from farm canal drainage over the entire duration of the drainage event.

Morris Water Maze Experiment

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Cited by 223 •

2008

The Morris water maze is a well-accepted tool used to document the involvement of the hippocampus in a behavioral task.

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