Name: Bloedafnamemethode door de muur heen om slaapverstoring in klinische omgevingen te minimaliseren (Video) | JoVE Journal
Uploaded: 2025-06-13T14:00:00.000+00:00
Duration: 6 min 39 s
Description: Leer een minimaal invasieve bloedafnamemethode door de muur heen voor slaaponderzoek naar circadiane ritmes en cardiometabole gezondheid. Deze techniek maakt continue 24-uurs monitoring mogelijk zonder de slaap van proefpersonen te verstoren.

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5 minutes

<ol><li>Cox, K. H., Takahashi, J. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Circadian+clock+genes+and+the+transcriptional+architecture+of+the+clock+mechanism%5BTitle%5D)+AND+%22J+Mol+Endocrinol%22%5BJournal%5D)">Circadian clock genes and the transcriptional architecture of the clock mechanism.</a> J Mol Endocrinol. 63 (4), R93-R102 (2019).</li>
<li>Broussard, J. L., et al. <a target="_blank" href="http://scholar.google.com/scholar?hl=en&safe=off&q=author%3aBroussard%2C+JL+%22Biological+Timekeeping%3A+Clocks%2C+Rhythms+and+Behaviour%22">Biological Timekeeping: Clocks, Rhythms and Behaviour</a>. , Springer. India. (2017).</li>
<li>Chellappa, S. L., Vujovic, N., Williams, J. S., Scheer, F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Impact+of+circadian+disruption+on+cardiovascular+function+and+disease%5BTitle%5D)+AND+%22Trends+Endocrinol+Metab%22%5BJournal%5D)">Impact of circadian disruption on cardiovascular function and disease.</a> Trends Endocrinol Metab. 30 (10), 767-779 (2019).</li>
<li>Broussard, J. L., Van Cauter, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Disturbances+of+sleep+and+circadian+rhythms%3A+novel+risk+factors+for+obesity%5BTitle%5D)+AND+%22Curr+Opin+Endocrinol+Diabetes+Obes%22%5BJournal%5D)">Disturbances of sleep and circadian rhythms: novel risk factors for obesity.</a> Curr Opin Endocrinol Diabetes Obes. 23 (5), 353-359 (2016).</li>
<li>Hanlon, E., Van Cauter, E. V., Tasali, E., Broussard, J. <a target="_blank" href="http://scholar.google.com/scholar?hl=en&safe=off&q=author%3aHanlon%2C+E+%22Endocrine+Physiology+in+Relation+to+Sleep+and+Sleep+Disturbances.+Principles+and+Pract+Sleep+Medicine%22">Endocrine Physiology in Relation to Sleep and Sleep Disturbances. Principles and Pract Sleep Medicine</a>. , Elsevier Saunders, MO. (2021).</li>
<li>Prasad, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+smartphone+intervention+to+promote+time+restricted+eating+reduces+body+weight+and+blood+pressure+in+adults+with+overweight+and+obesity%3A+a+pilot+study%5BTitle%5D)+AND+%22Nutrients%22%5BJournal%5D)">A smartphone intervention to promote time restricted eating reduces body weight and blood pressure in adults with overweight and obesity: a pilot study.</a> Nutrients. 13 (7), 2148(2021).</li>
<li>Procopio, S. B., Esser, K. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Clockwork+conditioning%3A+aligning+the+skeletal+muscle+clock+with+time-of-day+exercise+for+cardiometabolic+health%5BTitle%5D)+AND+%22J+Mol+Cell+Cardiol%22%5BJournal%5D)">Clockwork conditioning: aligning the skeletal muscle clock with time-of-day exercise for cardiometabolic health.</a> J Mol Cell Cardiol. 198, 36-44 (2025).</li>
<li>Holtman, S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Changes+in+circadian+timing+following+a+one-week+in-home+sleep+extension+manipulation+in+habitually+short-sleeping+adolescents%5BTitle%5D)+AND+%22Sleep%22%5BJournal%5D)">Changes in circadian timing following a one-week in-home sleep extension manipulation in habitually short-sleeping adolescents.</a> Sleep. 48 (2), zsae273(2024).</li>
<li>Chellappa, S. L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Daytime+eating+prevents+internal+circadian+misalignment+and+glucose+intolerance+in+night+work%5BTitle%5D)+AND+%22Sci+Adv%22%5BJournal%5D)">Daytime eating prevents internal circadian misalignment and glucose intolerance in night work.</a> Sci Adv. 7, eabg9910(2021).</li>
<li>Skene, D. J., Arendt, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Human+circadian+rhythms%3A+physiological+and+therapeutic+relevance+of+light+and+melatonin%5BTitle%5D)+AND+%22Ann+Clin+Biochem%22%5BJournal%5D)">Human circadian rhythms: physiological and therapeutic relevance of light and melatonin.</a> Ann Clin Biochem. 43 (Pt 5), 344-353 (2006).</li>
<li>Powell, D. J., Schlotz, W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Daily+life+stress+and+the+cortisol+awakening+response%3A+testing+the+anticipation+hypothesis%5BTitle%5D)+AND+%22PLoS+One%22%5BJournal%5D)">Daily life stress and the cortisol awakening response: testing the anticipation hypothesis.</a> PLoS One. 7 (12), e52067(2012).</li>
<li>Wright, K. P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Influence+of+sleep+deprivation+and+circadian+misalignment+on+cortisol%2C+inflammatory+markers%2C+and+cytokine+balance%5BTitle%5D)+AND+%22Brain+Behav+Immun%22%5BJournal%5D)">Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance.</a> Brain Behav Immun. 47, 24-34 (2015).</li>
<li>Ikegami, K., Refetoff, S., Van Cauter, E., Yoshimura, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Interconnection+between+circadian+clocks+and+thyroid+function%5BTitle%5D)+AND+%22Nat+Rev+Endocrinol%22%5BJournal%5D)">Interconnection between circadian clocks and thyroid function.</a> Nat Rev Endocrinol. 15 (10), 590-600 (2019).</li>
<li>Kessler, L., Nedeltcheva, A., Imperial, J., Penev, P. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Changes+in+serum+TSH+and+free+T4+during+human+sleep+restriction%5BTitle%5D)+AND+%22Sleep%22%5BJournal%5D)">Changes in serum TSH and free T4 during human sleep restriction.</a> Sleep. 33 (8), 1115-1118 (2010).</li>
<li>Van Cauter, E., Plat, L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Physiology+of+growth+hormone+secretion+during+sleep%5BTitle%5D)+AND+%22J+Pediatr%22%5BJournal%5D)">Physiology of growth hormone secretion during sleep.</a> J Pediatr. 128 (5 Pt 2), S32-S37 (1996).</li>
<li>Morselli, L., Leproult, R., Balbo, M., Spiegel, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Role+of+sleep+duration+in+the+regulation+of+glucose+metabolism+and+appetite%5BTitle%5D)+AND+%22Best+Pract+Res+Clin+Endocrinol+Metab%22%5BJournal%5D)">Role of sleep duration in the regulation of glucose metabolism and appetite.</a> Best Pract Res Clin Endocrinol Metab. 24 (5), 687-702 (2010).</li>
<li>Kapcala, L. P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Twenty-four-hour+prolactin+secretory+patterns+in+women+with+galactorrhea%2C+normal+menses%2C+normal+random+prolactin+levels+and+abnormal+sellar+tomograms%5BTitle%5D)+AND+%22J+Endocrinol+Invest%22%5BJournal%5D)">Twenty-four-hour prolactin secretory patterns in women with galactorrhea, normal menses, normal random prolactin levels and abnormal sellar tomograms.</a> J Endocrinol Invest. 7 (5), 455-460 (1984).</li>
<li>Sassin, J. F., Frantz, A. G., Kapen, S., Weitzman, E. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+nocturnal+rise+of+human+prolactin+is+dependent+on+sleep%5BTitle%5D)+AND+%22J+Clin+Endocrinol+Metab%22%5BJournal%5D)">The nocturnal rise of human prolactin is dependent on sleep.</a> J Clin Endocrinol Metab. 37 (3), 436-440 (1973).</li>
<li>Chaput, J. -P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+role+of+insufficient+sleep+and+circadian+misalignment+in+obesity%5BTitle%5D)+AND+%22Nat+Rev+Endocrinol%22%5BJournal%5D)">The role of insufficient sleep and circadian misalignment in obesity.</a> Nat Rev Endocrinol. 19 (2), 82-97 (2023).</li>
<li>Broussard, J. L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Sleep+restriction+increases+free+fatty+acids+in+healthy+men%5BTitle%5D)+AND+%22Diabetologia%22%5BJournal%5D)">Sleep restriction increases free fatty acids in healthy men.</a> Diabetologia. 58 (4), 791-798 (2015).</li>
<li>Vaughn, L. K., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Endocannabinoid+signalling%3A+has+it+got+rhythm%5BTitle%5D)+AND+%22Br+J+Pharmacol%22%5BJournal%5D)">Endocannabinoid signalling: has it got rhythm.</a> Br J Pharmacol. 160 (3), 530-543 (2010).</li>
<li>Lindgren, O., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Differential+islet+and+incretin+hormone+responses+in+morning+versus+afternoon+after+standardized+meal+in+healthy+men%5BTitle%5D)+AND+%22J+Clin+Endocrinol+Metab%22%5BJournal%5D)">Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men.</a> J Clin Endocrinol Metab. 94 (8), 2887-2892 (2009).</li>
<li>Wesselius, H. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Quality+and+quantity+of+sleep+and+factors+associated+with+sleep+disturbance+in+hospitalized+patients%5BTitle%5D)+AND+%22JAMA+Intern+Med%22%5BJournal%5D)">Quality and quantity of sleep and factors associated with sleep disturbance in hospitalized patients.</a> JAMA Intern Med. 178 (9), 1201-1208 (2018).</li>
<li>Markwald, R. R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Impact+of+insufficient+sleep+on+total+daily+energy+expenditure%2C+food+intake%2C+and+weight+gain%5BTitle%5D)+AND+%22Proc+Natl+Acad+Sci+U+S+A%22%5BJournal%5D)">Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain.</a> Proc Natl Acad Sci U S A. 110 (14), 5695-5700 (2013).</li>
<li>McHill, A. W., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Impact+of+circadian+misalignment+on+energy+metabolism+during+simulated+nightshift+work%5BTitle%5D)+AND+%22Proc+Natl+Acad+Sci+U+S+A%22%5BJournal%5D)">Impact of circadian misalignment on energy metabolism during simulated nightshift work.</a> Proc Natl Acad Sci U S A. 111 (48), 17302-17307 (2014).</li>
<li>Depner, C. M., Melanson, E. L., McHill, A. W., Wright, K. P. Jr <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mistimed+food+intake+and+sleep+alters+24-hour+time-of-day+patterns+of+the+human+plasma+proteome%5BTitle%5D)+AND+%22Proc+Natl+Acad+Sci+U+S+A%22%5BJournal%5D)">Mistimed food intake and sleep alters 24-hour time-of-day patterns of the human plasma proteome.</a> Proc Natl Acad Sci U S A. 115 (23), E5390-E5399 (2018).</li>
<li>Mullington, J. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Sleep+loss+reduces+diurnal+rhythm+amplitude+of+leptin+in+healthy+men%5BTitle%5D)+AND+%22J+Neuroendocrinol%22%5BJournal%5D)">Sleep loss reduces diurnal rhythm amplitude of leptin in healthy men.</a> J Neuroendocrinol. 15 (9), 851-854 (2003).</li>
<li>Ona, E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+technique+for+improved+blood+sampling+during+sleep+studies%5BTitle%5D)+AND+%22Psychophysiology%22%5BJournal%5D)">A technique for improved blood sampling during sleep studies.</a> Psychophysiology. 31 (6), 609-610 (1994).</li>
<li>Schlierf, G., Dorow, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Diurnal+patterns+of+triglycerides%2C+free+fatty+acids%2C+blood+sugar%2C+and+insulin+during+carbohydrate-induction+in+man+and+their+modification+by+nocturnal+suppression+of+lipolysis%5BTitle%5D)+AND+%22J+Clin+Invest%22%5BJournal%5D)">Diurnal patterns of triglycerides, free fatty acids, blood sugar, and insulin during carbohydrate-induction in man and their modification by nocturnal suppression of lipolysis.</a> J Clin Invest. 52 (3), 732-740 (1973).</li>
<li>Schlierf, G., Reinheimer, W., Stossberg, V. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Diurnal+patterns+of+plasma+triglycerides+and+free+fatty+acids+in+normal+subjects+and+in+patients+with+endogenous+%28type+IV%29+hyperlipoproteinemia%5BTitle%5D)+AND+%22Nutr+Metab%22%5BJournal%5D)">Diurnal patterns of plasma triglycerides and free fatty acids in normal subjects and in patients with endogenous (type IV) hyperlipoproteinemia.</a> Nutr Metab. 13 (2), 80-91 (1971).</li>
<li>Swanson, C. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((turnover+markers+after+sleep+restriction+and+circadian+disruption%3A+a+mechanism+for+sleep-related+bone+loss+in+humans%5BTitle%5D)+AND+%22J+Clin+Endocrinol+Metab%22%5BJournal%5D)">turnover markers after sleep restriction and circadian disruption: a mechanism for sleep-related bone loss in humans.</a> J Clin Endocrinol Metab. 102 (10), 3722-3730 (2017).</li>
<li>Van Cauter, E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Modulation+of+glucose+regulation+and+insulin+secretion+by+circadian+rhythmicity+and+sleep%5BTitle%5D)+AND+%22J+Clin+Invest%22%5BJournal%5D)">Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep.</a> J Clin Invest. 88 (3), 934-942 (1991).</li>
<li>Rynders, C. A., Morton, S. J., Bessesen, D. H., Wright, K. P. Jr, Broussard, J. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Circadian+rhythm+of+substrate+oxidation+and+hormonal+regulators+of+energy+balance%5BTitle%5D)+AND+%22Obesity+%28Silver+Spring%29%22%5BJournal%5D)">Circadian rhythm of substrate oxidation and hormonal regulators of energy balance.</a> Obesity (Silver Spring). 28 (Suppl 1), S104-S113 (2020).</li>
<li>Thosar, S. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Circadian+rhythm+of+vascular+function+in+midlife+adults%5BTitle%5D)+AND+%22Arterioscler+Thromb+Vasc+Biol%22%5BJournal%5D)">Circadian rhythm of vascular function in midlife adults.</a> Arterioscler Thromb Vasc Biol. 39 (6), 1203-1211 (2019).</li>
<li>Thosar, S. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Morning+impairment+in+vascular+function+is+unrelated+to+overnight+sleep+or+the+inactivity+that+accompanies+sleep%5BTitle%5D)+AND+%22Am+J+Physiol+Regul+Integr+Comp+Physiol%22%5BJournal%5D)">Morning impairment in vascular function is unrelated to overnight sleep or the inactivity that accompanies sleep.</a> Am J Physiol Regul Integr Comp Physiol. 315 (5), R986-R993 (2018).</li>
<li>Dimsdale, J. E., Coy, T., Ziegler, M. G., Ancoli-Israel, S., Clausen, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+effect+of+sleep+apnea+on+plasma+and+urinary+catecholamines%5BTitle%5D)+AND+%22Sleep%22%5BJournal%5D)">The effect of sleep apnea on plasma and urinary catecholamines.</a> Sleep. 18 (5), 377-381 (1995).</li>
<li>Klerman, E. B., Gershengorn, H. B., Duffy, J. F., Kronauer, R. E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Comparisons+of+the+variability+of+three+markers+of+the+human+circadian+pacemaker%5BTitle%5D)+AND+%22J+Biol+Rhythms%22%5BJournal%5D)">Comparisons of the variability of three markers of the human circadian pacemaker.</a> J Biol Rhythms. 17 (2), 181-193 (2002).</li>
<li>Benloucif, S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Measuring+melatonin+in+humans%5BTitle%5D)+AND+%22J+Clin+Sleep+Med%22%5BJournal%5D)">Measuring melatonin in humans.</a> J Clin Sleep Med. 4 (1), 66-69 (2008).</li>
<li>Lammers, W. J., Badia, P., Hughes, R., Harsh, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Temperature%2C+time-of-night+of+testing%2C+and+responsiveness+to+stimuli+presented+while+sleeping%5BTitle%5D)+AND+%22Psychophysiology%22%5BJournal%5D)">Temperature, time-of-night of testing, and responsiveness to stimuli presented while sleeping.</a> Psychophysiology. 28 (4), 463-467 (1991).</li>
<li>Alikhan, R., Forster, R., Cohen, A. T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Heparin+for+the+prevention+of+venous+thromboembolism+in+acutely+ill+medical+patients+%28excluding+stroke+and+myocardial+infarction%29%5BTitle%5D)+AND+%22Cochrane+Database+Syst+Rev%22%5BJournal%5D)">Heparin for the prevention of venous thromboembolism in acutely ill medical patients (excluding stroke and myocardial infarction).</a> Cochrane Database Syst Rev. 2014 (5), CD003747(2014).</li>
<li>Roth, B., Ekelund, M., Fan, B. G., Ekstrom, U., Nilsson-Ehle, P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effects+of+heparin+and+low+molecular+weight+heparin+on+lipid+transport+during+parenteral+feeding+in+the+rat%5BTitle%5D)+AND+%22Acta+Anaesthesiol+Scand%22%5BJournal%5D)">Effects of heparin and low molecular weight heparin on lipid transport during parenteral feeding in the rat.</a> Acta Anaesthesiol Scand. 40 (1), 102-111 (1996).</li>
<li>Weintraub, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Continuous+intravenous+heparin+administration+in+humans+causes+a+decrease+in+serum+lipolytic+activity+and+accumulation+of+chylomicrons+in+circulation%5BTitle%5D)+AND+%22J+Lipid+Res%22%5BJournal%5D)">Continuous intravenous heparin administration in humans causes a decrease in serum lipolytic activity and accumulation of chylomicrons in circulation.</a> J Lipid Res. 35 (2), 229-238 (1994).</li>
<li>Schallom, M. E., Prentice, D., Sona, C., Micek, S. T., Skrupky, L. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Heparin+or+0.9%25+sodium+chloride+to+maintain+central+venous+catheter+patency%3A+a+randomized+trial%5BTitle%5D)+AND+%22Crit+Care+Med%22%5BJournal%5D)">Heparin or 0.9% sodium chloride to maintain central venous catheter patency: a randomized trial.</a> Crit Care Med. 40 (6), 1820-1826 (2012).</li>
<li>Rahman, S. A., Wright, K. P. Jr, Lockley, S. W., Czeisler, C. A., Gronfier, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Characterizing+the+temporal+dynamics+of+melatonin+and+cortisol+changes+in+response+to+nocturnal+light+exposure%5BTitle%5D)+AND+%22Sci+Rep%22%5BJournal%5D)">Characterizing the temporal dynamics of melatonin and cortisol changes in response to nocturnal light exposure.</a> Sci Rep. 9 (1), 19720(2019).</li>
</ol>

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bloedafnamemethode door de muur heen om slaapverstoring in klinische omgevingen te minimaliseren

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings

Bloedafnamemethode door de muur heen om slaapverstoring in klinische omgevingen te minimaliseren

Physiological rhythms, including diurnal and circadian rhythms, play a critical role in health, with disturbances increasingly linked to cardiovascular ...

through-wall-blood-sampling-method-to-minimize-sleep-disruption

Research

JoVE Journal

Medicine

Geneeskunde

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Hier presenteren we een methode om dagritmes in prestaties te onderzoeken na nauwkeurige categorisering van deelnemers in circadiane fenotypegroepen op basis van de München ChronoType Questionnaire, gouden standaard circadiane fase biomarkers en actigrafische metingen.

Human Circadian Phenotyping en Diurnal Performance Testing in de echte wereld

Het huidige protocol beschrijft een eenvoudige en efficiënte methode voor het verzamelen van bloed uit de subclavia-ader bij ratten. Het maakt snelle, tijdige en gemakkelijk identificeerbare bemonstering zonder anesthesie mogelijk en verkrijgt bloed van hoge kwaliteit door herhaalde monsterverzameling.

Repetitieve bloedafname uit de subclavia-ader van bewuste rat

Het huidige protocol beschrijft een eenvoudige en efficiënte methode voor de real-time en dynamische verzameling van rattenhartbloed met behulp van de microdialysetechniek.

Dynamische continue bloedextractie uit het rattenhart via niet-invasieve microdialysetechniek

Het protocol toont herhaalde cerebrospinale vocht- en bloedafname van epileptische ratten die parallel worden uitgevoerd met continue video-elektro-encefalogram (EEG)-monitoring. Deze zijn van groot belang voor het onderzoeken van mogelijke verbanden tussen veranderingen in verschillende lichaamsvloeistofmoleculen en epileptische activiteit.

Bemonstering van hersenvocht en bloed uit laterale staartader bij ratten tijdens EEG-opnames

De pulsatiliteit van luteïniserend hormoon (LH) is een kenmerk van de voortplantingsfunctie. We beschrijven een protocol voor het op afstand activeren van specifieke neuronale populaties gekoppeld aan seriële geautomatiseerde bloedafname. Deze techniek maakt getimede hormonale modulatie, multiplexing en het minimaliseren van manipulatie-effecten op LH-niveaus mogelijk bij bewuste, vrij bewegende en ongestoorde dieren.

Neuronale activering op afstand in combinatie met geautomatiseerde bloedafname om circulerend luteïniserend hormoon bij muizen te induceren en te meten

Hier presenteren we een combinatie van effectieve rattenbeperking en subclavia-aderpunctiemethoden die snelle, veilige en herhaalde bloedafname bij ratten zonder verdoving mogelijk maken.

Bloedafname van subclavia-aderen bij bewuste ratten

Leer een minimaal invasieve bloedafnamemethode door de muur heen voor slaaponderzoek naar circadiane ritmes en cardiometabole gezondheid. Deze techniek maakt continue 24-uurs monitoring mogelijk zonder de slaap van proefpersonen te verstoren.

Bloedafnamemethode door de muur heen om slaapverstoring in klinische omgevingen te minimaliseren

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