Name: Implantatie van elektro-encefalogram en elektrocardiogram telemetrieapparaten in neonatale konijnenkits (Video) | JoVE Journal
Uploaded: 2025-02-28T13:50:00.000+00:00
Duration: 6 min 46 s
Description: Leer de implantatie van EEG- en ECG-telemetrieapparaten in neonatale konijnenkits voor continu neurologisch en cardiaal onderzoek. Deze methode ondersteunt studies naar plotse dood bij epilepsie.

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<ol><li>Bagnall, R. D., Crompton, D. E., Semsarian, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Genetic+Basis+of+Sudden+Unexpected+Death+in+Epilepsy%5BTitle%5D)+AND+%22Front+Neurol%22%5BJournal%5D)">Genetic Basis of Sudden Unexpected Death in Epilepsy.</a> Front Neurol. 8, 348(2017).</li>
<li>Surges, R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Pathologic+cardiac+repolarization+in+pharmacoresistant+epilepsy+and+its+potential+role+in+sudden+unexpected+death+in+epilepsy%3A+a+case-control+study%5BTitle%5D)+AND+%22Epilepsia%22%5BJournal%5D)">Pathologic cardiac repolarization in pharmacoresistant epilepsy and its potential role in sudden unexpected death in epilepsy: a case-control study.</a> Epilepsia. 51 (2), 233-242 (2010).</li>
<li>Surges, R., Thijs, R. D., Tan, H. L., Sander, J. W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Sudden+unexpected+death+in+epilepsy%3A+risk+factors+and+potential+pathomechanisms%5BTitle%5D)+AND+%22Nat+Rev+Neurol%22%5BJournal%5D)">Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms.</a> Nat Rev Neurol. 5 (9), 492-504 (2009).</li>
<li>Shorvon, S., Tomson, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Sudden+unexpected+death+in+epilepsy%5BTitle%5D)+AND+%22Lancet%22%5BJournal%5D)">Sudden unexpected death in epilepsy.</a> Lancet. 378 (9808), 2028-2038 (2011).</li>
<li>Schuele, S. U., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Video-electrographic+and+clinical+features+in+patients+with+ictal+asystole%5BTitle%5D)+AND+%22Neurology%22%5BJournal%5D)">Video-electrographic and clinical features in patients with ictal asystole.</a> Neurology. 69 (5), 434-441 (2007).</li>
<li>Massey, C. A., Sowers, L. P., Dlouhy, B. J., Richerson, G. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mechanisms+of+sudden+unexpected+death+in+epilepsy%3A+the+pathway+to+prevention%5BTitle%5D)+AND+%22Nat+Rev+Neurol%22%5BJournal%5D)">Mechanisms of sudden unexpected death in epilepsy: the pathway to prevention.</a> Nat Rev Neurol. 10 (5), 271-282 (2014).</li>
<li>Sahly, A. N., Shevell, M., Sadleir, L. G., Myers, K. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((SUDEP+risk+and+autonomic+dysfunction+in+genetic+epilepsies%5BTitle%5D)+AND+%22Auton+Neurosci%22%5BJournal%5D)">SUDEP risk and autonomic dysfunction in genetic epilepsies.</a> Auton Neurosci. 237, 102907(2022).</li>
<li>Cooper, M. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mortality+in+Dravet+syndrome%5BTitle%5D)+AND+%22Epilepsy+Res%22%5BJournal%5D)">Mortality in Dravet syndrome.</a> Epilepsy Res. 128, 43-47 (2016).</li>
<li>Negishi, Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((SCN8A-related+developmental+and+epileptic+encephalopathy+with+ictal+asystole+requiring+cardiac+pacemaker+implantation%5BTitle%5D)+AND+%22Brain+Dev%22%5BJournal%5D)">SCN8A-related developmental and epileptic encephalopathy with ictal asystole requiring cardiac pacemaker implantation.</a> Brain Dev. 43 (7), 804-808 (2021).</li>
<li>Meisler, M. H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((SCN8A+encephalopathy%3A+Research+progress+and+prospects%5BTitle%5D)+AND+%22Epilepsia%22%5BJournal%5D)">SCN8A encephalopathy: Research progress and prospects.</a> Epilepsia. 57 (7), 1027-1035 (2016).</li>
<li>Watanabe, H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Sodium+channel+%CE%B21+subunit+mutations+associated+with+Brugada+syndrome+and+cardiac+conduction+disease+in+humans%5BTitle%5D)+AND+%22J+Clin+Invest%22%5BJournal%5D)">Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans.</a> J Clin Invest. 118 (6), 2260-2268 (2008).</li>
<li>Goldman, A. M., Glasscock, E., Yoo, J., Chen, T. T., Klassen, T. L., Noebels, J. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Arrhythmia+in+heart+and+brain%3A+KCNQ1+mutations+link+epilepsy+and+sudden+unexplained+death%5BTitle%5D)+AND+%22Sci+Transl+Med%22%5BJournal%5D)">Arrhythmia in heart and brain: KCNQ1 mutations link epilepsy and sudden unexplained death.</a> Sci Transl Med. 1 (2), 2ra6(2009).</li>
<li>Nerbonne, J. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mouse+models+of+arrhythmogenic+cardiovascular+disease%3A+challenges+and+opportunities%5BTitle%5D)+AND+%22Curr+Opin+Pharmacol%22%5BJournal%5D)">Mouse models of arrhythmogenic cardiovascular disease: challenges and opportunities.</a> Curr Opin Pharmacol. 15, 107-114 (2014).</li>
<li>Frasier, C. R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Channelopathy+as+a+SUDEP+Biomarker+in+Dravet+Syndrome+patient-derived+cardiac+myocytes%5BTitle%5D)+AND+%22Stem+Cell+Rep%22%5BJournal%5D)">Channelopathy as a SUDEP Biomarker in Dravet Syndrome patient-derived cardiac myocytes.</a> Stem Cell Rep. 11 (3), 626-634 (2018).</li>
<li>Camacho, P., Fan, H., Liu, Z., He, J. -Q. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Small+mammalian+animal+models+of+heart+disease%5BTitle%5D)+AND+%22Am+J+Cardiovasc%22%5BJournal%5D)">Small mammalian animal models of heart disease.</a> Am J Cardiovasc. 6 (3), 70-80 (2016).</li>
<li>Brodbelt, D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Perioperative+mortality+in+small+animal+anaesthesia%5BTitle%5D)+AND+%22Vet+J%22%5BJournal%5D)">Perioperative mortality in small animal anaesthesia.</a> Vet J. 182 (2), 152-161 (2009).</li>
<li>Lee, H. W., Machin, H., Adami, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Peri-anaesthetic+mortality+and+nonfatal+gastrointestinal+complications+in+pet+rabbits%3A+a+retrospective+study+on+210+cases%5BTitle%5D)+AND+%22Vet+Anaes+Anal%22%5BJournal%5D)">Peri-anaesthetic mortality and nonfatal gastrointestinal complications in pet rabbits: a retrospective study on 210 cases.</a> Vet Anaes Anal. 45 (4), 520-528 (2018).</li>
<li>Comolli, J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Comparison+of+endoscopic+endotracheal+intubation+and+the+v-gel+supraglottic+airway+device+for+spontaneously+ventilating+New+Zealand+white+rabbits+undergoing+ovariohysterectomy%5BTitle%5D)+AND+%22Vet+Rec%22%5BJournal%5D)">Comparison of endoscopic endotracheal intubation and the v-gel supraglottic airway device for spontaneously ventilating New Zealand white rabbits undergoing ovariohysterectomy.</a> Vet Rec. 187 (10), e84-e84 (2020).</li>
<li>Grint, N. J., Sayers, I. R., Cecchi, R., Harley, R., Day, M. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Postanaesthetic+tracheal+strictures+in+three+rabbits%5BTitle%5D)+AND+%22Lab+Anim%22%5BJournal%5D)">Postanaesthetic tracheal strictures in three rabbits.</a> Lab Anim. 40 (3), 301-308 (2006).</li>
<li>Phaneuf, L. R., Barker, S., Groleau, M. A., Turner, P. V. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Tracheal+injury+after+endotracheal+intubation+and+anesthesia+in+rabbits%5BTitle%5D)+AND+%22J+Am+Assoc+Lab+Anim+Sci%22%5BJournal%5D)">Tracheal injury after endotracheal intubation and anesthesia in rabbits.</a> J Am Assoc Lab Anim Sci. 45 (6), 67-72 (2006).</li>
<li>Quesenberry, K. E., Orcutt, C. J., Mans, C., Carpenter, J. W. Gastrointestinal Diseases of Rabbits. <a target="_blank" href="http://scholar.google.com/scholar?hl=en&safe=off&q=author%3aQuesenberry%2C+KE+%22Ferrets%2C+Rabbits%2C+and+Rodents%22">Ferrets, Rabbits, and Rodents</a>. , Elsevier. MO. (2020).</li>
<li>Desai, A., Macrae, D. <a target="_blank" href="http://scholar.google.com/scholar?hl=en&safe=off&q=author%3aDesai%2C+A+%22Cardiovascular+Physiology+in+Infants%2C+Children%2C+and+Adolescents.+Pediatric+and+Congenital+Cardiology%2C+Cardiac+Surgery+and+Intensive+Care%22">Cardiovascular Physiology in Infants, Children, and Adolescents. Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care</a>. , Springer. London. (2020).</li>
<li>Bansal, N., Momin, S., Bansal, R., Venkata, S. K. R. G., Ruser, L., Yusuf, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Pharmacokinetics+of+drugs%3A+newborn+perspective%5BTitle%5D)+AND+%22Pediatr+Med%22%5BJournal%5D)">Pharmacokinetics of drugs: newborn perspective.</a> Pediatr Med. 7, 19(2024).</li>
<li>Trachsel, D., Erb, T. O., Hammer, J., von Ungern-Sternberg, B. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Developmental+respiratory+physiology%5BTitle%5D)+AND+%22Paediat+Anaesth%22%5BJournal%5D)">Developmental respiratory physiology.</a> Paediat Anaesth. 32 (2), 108-117 (2022).</li>
<li>Benito, S., Hadley, S., Camprubí-Camprubí, M., Sanchez-de-Toledo, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Blind+endotracheal+intubation+in+neonatal+rabbits%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Blind endotracheal intubation in neonatal rabbits.</a> J Vis Exp. 168, e61874(2021).</li>
<li>Okamoto, S., Matsuura, N., Ichinohe, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effects+of+volatile+anesthetics+on+oral+tissue+blood+flow+in+rabbits%3A+A+comparison+among+isoflurane%2C+sevoflurane%2C+and+desflurane%5BTitle%5D)+AND+%22J+Oral+Maxillofac+Surg%22%5BJournal%5D)">Effects of volatile anesthetics on oral tissue blood flow in rabbits: A comparison among isoflurane, sevoflurane, and desflurane.</a> J Oral Maxillofac Surg. 73 (9), 1714.e1-1714.e8 (2015).</li>
<li>Elshalakany, N. A., Salah, A. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Comparative+study%3A+evaluation+of+the+effect+of+sevoflurane+versus+isoflurane+in+general+anesthesia+for+pediatric+patients+undergoing+cardiac+catheterization%5BTitle%5D)+AND+%22Egypt+J+Anaesth%22%5BJournal%5D)">Comparative study: evaluation of the effect of sevoflurane versus isoflurane in general anesthesia for pediatric patients undergoing cardiac catheterization.</a> Egypt J Anaesth. 38 (1), 409-414 (2022).</li>
<li>Anjana, R. R., Parikh, P. V., Mahla, J. K., Kelawala, D. N., Patel, K. P., Ashwath, S. N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Comparative+evaluation+of+isoflurane+and+sevoflurane+in+avian+patients%5BTitle%5D)+AND+%22Vet+World%22%5BJournal%5D)">Comparative evaluation of isoflurane and sevoflurane in avian patients.</a> Vet World. 14 (5), 1067-1073 (2021).</li>
<li>Johnson, R. A., Striler, E., Sawyer, D. C., Brunson, D. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Comparison+of+isoflurane+with+sevoflurane+for+anesthesia+induction+and+recovery+in+adult+dogs%5BTitle%5D)+AND+%22Am+J+Vet+Res%22%5BJournal%5D)">Comparison of isoflurane with sevoflurane for anesthesia induction and recovery in adult dogs.</a> Am J Vet Res. 59 (4), 478-481 (1998).</li>
<li>Campbell, C., Nahrwold, M. L., Miller, D. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Clinical+comparison+of+sevoflurane+and+isoflurane+when+administered+with+nitrous+oxide+for+surgical+procedures+of+intermediate+duration%5BTitle%5D)+AND+%22Can+J+Anaesth%22%5BJournal%5D)">Clinical comparison of sevoflurane and isoflurane when administered with nitrous oxide for surgical procedures of intermediate duration.</a> Can J Anaesth. 42 (10), 884-890 (1995).</li>
<li>TerRiet, M. F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Which+is+most+pungent%3A+isoflurane%2C+sevoflurane%2C+or+desflurane%5BTitle%5D)+AND+%22Br+J+Anaesth%22%5BJournal%5D)">Which is most pungent: isoflurane, sevoflurane, or desflurane.</a> Br J Anaesth. 85 (2), 305-307 (2000).</li>
<li>Khanna, V. K., Pleuvry, B. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+study+of+naloxone+and+doxapram+as+agents+for+the+reversal+of+neuroleptanalgesic+respiratory+depression+in+the+conscious+rabbit%5BTitle%5D)+AND+%22Br+J+Anaesth%22%5BJournal%5D)">A study of naloxone and doxapram as agents for the reversal of neuroleptanalgesic respiratory depression in the conscious rabbit.</a> Br J Anaesth. 50 (9), 905-912 (1978).</li>
<li>Flecknell, P. A., Liles, J. H., Wootton, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Reversal+of+fentanyl%2Ffluanisone+neuroleptanalgesia+in+the+rabbit+using+mixed+agonist%2Fantagonist+opioids%5BTitle%5D)+AND+%22Lab+Anim%22%5BJournal%5D)">Reversal of fentanyl/fluanisone neuroleptanalgesia in the rabbit using mixed agonist/antagonist opioids.</a> Lab Anim. 23 (2), 147-155 (1989).</li>
<li>Shafford, H. L., Schadt, J. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Respiratory+and+cardiovascular+effects+of+buprenorphine+in+conscious+rabbits%5BTitle%5D)+AND+%22Vet+Anaesth+Analg%22%5BJournal%5D)">Respiratory and cardiovascular effects of buprenorphine in conscious rabbits.</a> Vet Anaesth Analg. 35 (4), 326-332 (2008).</li>
<li>Feldman, E. R., Singh, B., Mishkin, N. G., Lachenauer, E. R., Martin-Flores, M., Daugherity, E. K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effects+of+cisapride%2C+buprenorphine%2C+and+their+combination+on+gastrointestinal+transit+in+New+Zealand+white+rabbits%5BTitle%5D)+AND+%22J+Am+Assoc+Lab+Anim+Sci%22%5BJournal%5D)">Effects of cisapride, buprenorphine, and their combination on gastrointestinal transit in New Zealand white rabbits.</a> J Am Assoc Lab Anim Sci. 60 (2), 221-228 (2021).</li>
<li>Harcourt-Brown, F. M., Harcourt-Brown, S. F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Clinical+value+of+blood+glucose+measurement+in+pet+rabbits%5BTitle%5D)+AND+%22Vet+Rec%22%5BJournal%5D)">Clinical value of blood glucose measurement in pet rabbits.</a> Vet Rec. 170 (26), 674-674 (2012).</li>
<li>Rivera, D. A., Buglione, A. E., Ray, S. E., Schaffer, C. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((MousePZT%3A+A+simple%2C+reliable%2C+low-cost+device+for+vital+sign+monitoring+and+respiratory+gating+in+mice+under+anesthesia%5BTitle%5D)+AND+%22PLoS+One%22%5BJournal%5D)">MousePZT: A simple, reliable, low-cost device for vital sign monitoring and respiratory gating in mice under anesthesia.</a> PLoS One. 19 (3), e0299047(2024).</li>
<li>Nicou, C. M., Passaglia, C. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Characterization+of+intraocular+pressure+variability+in+conscious+rats%5BTitle%5D)+AND+%22Exp+Eye+Res%22%5BJournal%5D)">Characterization of intraocular pressure variability in conscious rats.</a> Exp Eye Res. 239, 109757(2024).</li>
<li>Sadko, K. J., Leishman, D. J., Bailie, M. B., Lauver, D. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+simple+accurate+method+for+concentration-QTc+analysis+in+preclinical+animal+models%5BTitle%5D)+AND+%22J+Pharmacol+Toxicol+Methods%22%5BJournal%5D)">A simple accurate method for concentration-QTc analysis in preclinical animal models.</a> J Pharmacol Toxicol Methods. 128, 107528(2024).</li>
<li>Vuong, J. S., Garrett, J. J., Connolly, M. J., York, A. R., Gross, R. E., Devergnas, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Head+mounted+telemetry+system+for+seizures+monitoring+and+sleep+scoring+on+non-human+primate%5BTitle%5D)+AND+%22J+Neurosci+Methods%22%5BJournal%5D)">Head mounted telemetry system for seizures monitoring and sleep scoring on non-human primate.</a> J Neurosci Methods. 346, 108915(2020).</li>
<li>Bosinski, C., Wagner, K., Zhou, X., Liu, L., Auerbach, D. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Multi-system+monitoring+for+identification+of+seizures%2C+arrhythmias+and+apnea+in+conscious+restrained+rabbits%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Multi-system monitoring for identification of seizures, arrhythmias and apnea in conscious restrained rabbits.</a> J Vis Exp. (169), e62256(2021).</li>
</ol>

<table><tbody><tr><td>1 inch elastische omslag - Coban of Vetwrap</td><td>3M</td><td>https://www.3m.com/3M/en_US/p/d/b00003186/</td><td></td></tr><tr><td>4-0 PDS monofilament naald</td><td>Ethicon</td><td>https://www.jnjmedtech.com/en-US/company/ethicon/all-products</td><td></td></tr><tr><td>5-0 Ethilon nylon naald</td><td>Ethicon</td><td>https://www.jnjmedtech.com/en-US/company/ethicon/all-products</td><td></td></tr><tr><td>Acquisitiecomputer</td><td>Dell</td><td>https://www.dell.com/en-us</td><td></td></tr><tr><td>Klevende chirurgische handdoeken</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Anesthesiecircuit - Jackson-Reevs met 0,5 L rebreathing zak</td><td>JorVet</td><td>J0248GA</td><td></td></tr><tr><td>Betadine scrub</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Bupivicaine (0,5%)</td><td>N/A</td><td>N/A</td><td>Verdund tot 2,5 mg/mL vóór toediening</td></tr><tr><td>Buprenorfine (0,3 mg/mL)</td><td>N/A</td><td>N/A</td><td>Verdund tot 0,03 mg/mL vóór toediening&nbsp;</td></tr><tr><td>Boor - 1,00 mm</td><td>Cell Point Scientific</td><td>60-1000</td><td>om schedel te boren</td></tr><tr><td>Cafazolin (1 g lyofiliseerd)</td><td>N/A</td><td>N/A</td><td>Verdund tot 50 mg/mL</td></tr><tr><td>Carprofen (50 mg/mL)</td><td>MWI Veterinary</td><td></td><td>Verdund tot 25 mg/mL vóór toediening</td></tr><tr><td>Wattenstaafjes</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Aangepaste 3-D gedrukte gezichtsmasker</td><td>N/A</td><td>https://www.thingiverse.com/thing:923725</td><td></td></tr><tr><td>Tandheelkundig acryl</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Diet Gel Criticare</td><td>Clear H2O</td><td>72-05-5042</td><td>Nutritionele ondersteuning&nbsp;</td></tr><tr><td>Dopper Gel - Aquasonic</td><td>Patterson&nbsp;</td><td>07-890-5542</td><td></td></tr><tr><td>Doppler - Vet-Dop2</td><td>Patterson</td><td>07-888-8986</td><td></td></tr><tr><td>Doxapram (20 mg/mL)</td><td>MWI Veterinary</td><td>N/A</td><td>Alleen in noodgevallen</td></tr><tr><td>Dumont #5 Fijne pincet</td><td>Fine Science Tools</td><td>11254-20</td><td>Voor het vasthouden van schroeven</td></tr><tr><td>Duraprep</td><td>3M</td><td>8630</td><td>Laatste huidvoorbereiding</td></tr><tr><td>ecgAuto data-analysesoftware</td><td>emka technologies</td><td>N/A</td><td></td></tr><tr><td>Epinefrine (1:1000)</td><td>MWI Veterinary</td><td>N/A</td><td>Alleen in noodgevallen</td></tr><tr><td>Gaas</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Glucometer ipet Pro</td><td>MWI Veterinary</td><td>63867</td><td>Monitoren als slecht herstel</td></tr><tr><td>Glycopyrrolate (0,2 mg/mL)</td><td>MWI Veterinary</td><td>N/A</td><td>Alleen in noodgevallen</td></tr><tr><td>Gramweegschaal</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Hemostaten</td><td>Fine Science Tools</td><td>13008-12</td><td>Draadlussen vasthouden tijdens het vastbinden van de lus op zijn plaats</td></tr><tr><td>Ideal Micro-boor</td><td>Cell Point Scientific</td><td>67-1204</td><td>Om schedel te boren</td></tr><tr><td>Incubator</td><td>DRE-veterinary (Infantia - NB1)</td><td>N/A</td><td></td></tr><tr><td>Inductiebox</td><td>VetEquip</td><td>941444</td><td></td></tr><tr><td>Infrarood verwarmingskussentje - RightTemp Jr</td><td>Kent Scientific Corporation</td><td>RT-0502</td><td></td></tr><tr><td>IOX2 data-acquisitiesoftware</td><td>emka technologies</td><td>N/A</td><td></td></tr><tr><td>IV-katheter - Covidein Monoject 26 G, 3/4 inch PTFE&nbsp;</td><td>Patterson&nbsp;</td><td>07-836-8494</td><td></td></tr><tr><td>Ketamine (100 mg/mL)</td><td>MWI Veterinary</td><td>N/A</td><td></td></tr><tr><td>Medische tape</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Smal patroon pincet - Recht/12 cm</td><td>Fine Science Tools</td><td>11002-12</td><td></td></tr><tr><td>Neonataal stethoscoop</td><td>Ultrascope</td><td>N/A</td><td></td></tr><tr><td>Olsen-Hegar Naaldhouder met schaar - 12 cm</td><td>Fine Science Tools</td><td>12002-12</td><td>Voor het hechten</td></tr><tr><td>Oftalmische zalf Puralube</td><td>MWI Veterinary</td><td>N/A</td><td>Toegediend aan beide ogen tijdens anesthesie</td></tr><tr><td>Oftalmische smeermiddel - Paralube Vet</td><td>Patterson&nbsp;</td><td>07-888-2572</td><td></td></tr><tr><td>Pulsoximeter (AccuWave Portable )</td><td>Patterson</td><td>07-892-9128</td><td>Voor voorbereiding en herstel; leest HR tot 400</td></tr><tr><td>Pulsoximeter (SDI - Vet/Ox plus 4700)</td><td>Heska</td><td>N/A</td><td>Intraoperatief; niet langer geproduceerd</td></tr><tr><td>Ontvanger</td><td>emka technologies</td><td>N/A</td><td>1 ontvanger voor elke 4 telemetrie-implantaten</td></tr><tr><td>Rectothermometer</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Schaar</td><td>Fine Science Tools</td><td>14002-12</td><td>Om doek te snijden</td></tr><tr><td>Schroevendraaier - 1,0 mm</td><td>N/A</td><td>N/A</td><td>Uit mini-schroevendraaierset voor elektronica</td></tr><tr><td>Schroeven 00-96 x 3/32 (2,4 mm)</td><td>Protech International</td><td>8L0X3905202F</td><td></td></tr><tr><td>Sevofluraan</td><td>MWI Veterinary</td><td></td><td>Onderhoudsanesthesie</td></tr><tr><td>Sevofluraan verdamper en anesthesieapparaat</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Huidlijm, Gluture</td><td>MWI Veterinary</td><td>34207</td><td>Spaarzaam aanbrengen met spuit</td></tr><tr><td>Kleine schaar</td><td>Fine Science Tools</td><td>14084-08</td><td></td></tr><tr><td>Steriele aluminiumfolie</td><td>N/A</td><td>N/A</td><td>Om draden te wikkelen voordat het dier wordt gedraaid&nbsp;</td></tr><tr><td>Steriele verfborstel</td><td>N/A</td><td>N/A</td><td>Om tandheelkundig acryl aan te brengen&nbsp;</td></tr><tr><td>Steriele zoutoplossing</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Steriele chirurgische handschoenen</td><td>N/A</td><td>N/A</td><td></td></tr><tr><td>Steriele ultrasone hoes</td><td>N/A</td><td>N/A</td><td>Om de boor te bedekken</td></tr><tr><td>Steriele water</td><td>N/A</td><td>N/A</td><td>Voor cefazolin reconstitutie</td></tr><tr><td>Chirurgische mesje

implantatie van elektro-encefalogram en elektrocardiogram telemetrieapparaten in neonatale konijnenkits

Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits

Implantatie van elektro-encefalogram en elektrocardiogram telemetrieapparaten in neonatale konijnenkits

Pathogenic variants in ion channel genes are associated with a high rate of sudden unexpected death in epilepsy (SUDEP). Mechanisms of SUDEP are poorly ...

implantation-electroencephalogram-electrocardiogram-telemetry-devices

Research

JoVE Journal

Medicine

Geneeskunde

This video demonstrates the procedure to implant EEG-ECG electrodes and attach respiratory probes in a rabbit model for acquiring and analyzing records of its bio signals.

Prepping Conscious Rabbit Model for Simultaneous Video-EEG-ECG-Oximetry-Capnography for Experimental Interventions: A Procedure to Implant EEE-ECG Electrodes and Attach Respiratory Probes in Rabbit Model

In this video, we show a procedure for simultaneous recording of video-EEG-ECG-capnography-oximetry data generated by inducing seizures in a rabbit model.

Intermittent Photic Stimulation in Rabbit Model: A Technique to Induce Epileptic Seizures and Simultaneously Record Multisystem Parameters

In this video, we demonstrate a multisystem monitoring method to evaluate neurological and cardiorespiratory abnormalities during intravenous injection of a seizure-inducing drug. The simultaneous monitoring of video EEG, ECG, oximetry, and capnography parameters helps to understand the real-time physiological changes associated with epileptic seizures.

Multisystem Monitoring of Epileptic Abnormalities in Rabbit: A Method for Simultaneous Video EEG, ECG, Capnography, and Oximetry Recording During Induced Seizures

Met behulp van gelijktijdige video-EEG-ECG-oximetrie-capnografie ontwikkelden we een methodologie om de gevoeligheid van konijnenmodellen te evalueren om uitgelokte hartritmestoornissen en aanvallen te ontwikkelen. Dit nieuwe opnamesysteem creëert een platform om de werkzaamheid en veiligheid van therapieën te testen en kan de complexe cascade van multi-systeemgebeurtenissen vastleggen die culmineren in plotselinge dood.

Multi-systeem monitoring voor identificatie van aanvallen, hartritmestoornissen en apneu bij bewuste ingehouden konijnen

De studie schetst een protocol voor het ontwerp, de productie en de plaatsing van een nieuw continu EEG/ECG-registratiesysteem bij konijnen. Dit bedrade systeem maakt continue EEG/ECG-opnames mogelijk van negen verschillende elektroden op het hoofd en de borst, wat uitgebreide beoordelingen van elektrische activiteit in de hersenen en het hart mogelijk maakt.

Chirurgische implantaatprocedure en bedradingsconfiguratie voor continue langdurige EEG/ECG-monitoring bij konijnen

Dit manuscript beschrijft een protocol voor het implanteren van telemeters in de muis om intrauterine drukken tijdens de zwangerschap te meten.

Intra-uteriene Telemetrie naar Mouse Contractiele druk te meten<em&gt; In Vivo</em

Het doel van dit protocol is om de systemische bloeddruk te beoordelen bij bewuste, vrij bewegende muizen met behulp van implanteerbare radio-telemetrie-apparaten.

Langdurige Bloeddruk meten in vrij bewegende muizen met behulp van telemetrie

Het doel van dit protocol is om de voorbereiding, de cultuur, de behandeling en het immunostaining van neonatale muizencochleaire explantanten aan te tonen. De techniek kan gebruikt worden als een in vitro screening tool bij het horen onderzoek.

Neonatale Murine Cochlear Explantietechniek als een<em&gt; In Vitro</em&gt; Screening Tool in Hearing Research

Het doel van dit protocol is bedoeld als een dierlijk model van cochleaire implantatie, die kan worden gebruikt om aan te pakken van een veelheid van onderzoeksvragen. Mogelijke toepassingen zijn onder andere de evaluatie van farmaceutische interventies of elektrische stimulatie voor gunstige effecten op de hoorzitting drempels of elektrode impedances.

Cochleaire implantatie in de cavia

We presenteren een ECG-protocol dat technisch eenvoudig, goedkoop, snel en betaalbaar is in kleine muizen en kan worden uitgevoerd met verbeterde gevoeligheid. We stellen deze methode voor als een screeningsbenadering voor het bestuderen van farmacologische agentia, genetische modificaties en ziektemodellen bij muizen.

Electrocardiogram Opnames in verdoofde muizen met lead II

Leer de implantatie van EEG- en ECG-telemetrieapparaten in neonatale konijnenkits voor continu neurologisch en cardiaal onderzoek. Deze methode ondersteunt studies naar plotse dood bij epilepsie.

Implantatie van elektro-encefalogram en elektrocardiogram telemetrieapparaten in neonatale konijnenkits

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