Name: Optimalisatie van fotoneuromodulatietechnieken om de rol van groen lichtgevende diodes bij pijnbestrijding te evalueren (Video) | JoVE Journal
Uploaded: 2025-03-28T14:30:00.000+00:00
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Description: Leer fotoneuromodulatie met groene LED voor pijnbestrijding bij ratten en mensen. Deze methode optimaliseert belichtingsparameters van 525 nm voor consistente toepassing in acute en chronische pijn.

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<ol><li>Alorfi, N. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Pharmacological+methods+of+Narrative+review+of+medication+used%5BTitle%5D)+AND+%22Int+J+Gen+Med%22%5BJournal%5D)">Pharmacological methods of Narrative review of medication used.</a> Int J Gen Med. 16, 3247-3256 (2023).</li>
<li>Cherny, N., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Strategies+to+manage+the+adverse+effects+of+oral+morphine%3A+an+evidence-based+report%5BTitle%5D)+AND+%22J+Clin+Oncol%22%5BJournal%5D)">Strategies to manage the adverse effects of oral morphine: an evidence-based report.</a> J Clin Oncol. 19 (9), 2542-2554 (2001).</li>
<li>Hanks, G. W., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Morphine+in+cancer+pain%3A+modes+of+administration.+Expert+Working+Group+of+the+European+Association+for+Palliative+Care%5BTitle%5D)+AND+%22BMJ%22%5BJournal%5D)">Morphine in cancer pain: modes of administration. Expert Working Group of the European Association for Palliative Care.</a> BMJ. 312 (7034), 823-826 (1996).</li>
<li>de Freitas, L. F., Hamblin, M. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Proposed+mechanisms+of+photobiomodulation+or+low-level+light+therapy%5BTitle%5D)+AND+%22IEEE+J+Sel+Top+Quantum+Electron%22%5BJournal%5D)">Proposed mechanisms of photobiomodulation or low-level light therapy.</a> IEEE J Sel Top Quantum Electron. 22 (3), 7000417(2016).</li>
<li>Pathak, M. A., Fitzpatrick, T. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+evolution+of+photochemotherapy+with+psoralens+and+UVA+%28PUVA%29%3A+2000+BC+to+1992+AD%5BTitle%5D)+AND+%22J+Photochem+Photobiol+B%22%5BJournal%5D)">The evolution of photochemotherapy with psoralens and UVA (PUVA): 2000 BC to 1992 AD.</a> J Photochem Photobiol B. 14 (1), 3-22 (1992).</li>
<li>Kemper, K. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((.%26%2334%3BLet+there+be+light.%26%2334%3B+Research+on+phototherapy%2C+light+therapy%2C+and+photobiomodulation+for+healing+-+Alternative+therapy+becomes+mainstream%5BTitle%5D)+AND+%22Complement+Ther+Med%22%5BJournal%5D)">.&#34;Let there be light.&#34; Research on phototherapy, light therapy, and photobiomodulation for healing - Alternative therapy becomes mainstream.</a> Complement Ther Med. 41, A1-A6 (2018).</li>
<li>Olesen, J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Headache+Classification+Committee+of+the+International+Headache+Society%28IHS%29%2C+The+International+Classification+of+Headache+Disorders%2C+3rd+edition%5BTitle%5D)+AND+%22Cephalalgia%22%5BJournal%5D)">Headache Classification Committee of the International Headache Society(IHS), The International Classification of Headache Disorders, 3rd edition.</a> Cephalalgia. 38 (1), 1-211 (2018).</li>
<li>Santiago, R., Gomes, S., Ozsarfati, J., Zitney, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Photobiomodulation+for+modulation+of+neuropathic+pain+and+improvement+of+scar+tissue%5BTitle%5D)+AND+%22Scars+Burn+Heal%22%5BJournal%5D)">Photobiomodulation for modulation of neuropathic pain and improvement of scar tissue.</a> Scars Burn Heal. 8, 20595131221134052(2022).</li>
<li>González-Muñoz, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Efficacy+of+photobiomodulation+therapy+in+the+treatment+of+pain+and+inflammation%3A+A+literature+review%5BTitle%5D)+AND+%22Healthcare+%28Basel%29%22%5BJournal%5D)">Efficacy of photobiomodulation therapy in the treatment of pain and inflammation: A literature review.</a> Healthcare (Basel). 11 (7), 938(2023).</li>
<li>Figueiro, M. G., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Tailored+lighting+intervention+improves+measures+of+sleep%2C+depression%2C+and+agitation+in+persons+with+Alzheimer%27s+disease+and+related+dementia+living+in+long-term+care+facilities%5BTitle%5D)+AND+%22Clin+Interv+Aging%22%5BJournal%5D)">Tailored lighting intervention improves measures of sleep, depression, and agitation in persons with Alzheimer's disease and related dementia living in long-term care facilities.</a> Clin Interv Aging. 9, 1527-1537 (2014).</li>
<li>Eastman, C. I., Young, M. A., Fogg, L. F., Liu, L., Meaden, P. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Bright+light+treatment+of+winter+depression%3A+A+placebo-controlled+trial%5BTitle%5D)+AND+%22Arch+Gen+Psychiatry%22%5BJournal%5D)">Bright light treatment of winter depression: A placebo-controlled trial.</a> Arch Gen Psychiatry. 55 (10), 883-889 (1998).</li>
<li>Martin, L. F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Evaluation+of+green+light+exposure+on+headache+frequency+and+quality+of+life+in+migraine+patients%3A+A+preliminary+one-way+cross-over+clinical+trial%5BTitle%5D)+AND+%22Cephalalgia%22%5BJournal%5D)">Evaluation of green light exposure on headache frequency and quality of life in migraine patients: A preliminary one-way cross-over clinical trial.</a> Cephalalgia. 41 (2), 135-147 (2021).</li>
<li>Martin, L. F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((light+antinociceptive+and+reversal+of+thermal+and+mechanical+hypersensitivity+effects+rely+on+endogenous+opioid+system+stimulation%5BTitle%5D)+AND+%22J+Pain%22%5BJournal%5D)">light antinociceptive and reversal of thermal and mechanical hypersensitivity effects rely on endogenous opioid system stimulation.</a> J Pain. 22 (12), 1646-1656 (2021).</li>
<li>Nelli, A., Wright, M. C., Gulur, P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Green+light-based+analgesia+-+novel+non-pharmacological+approach+to+fibromyalgia+pain%3A+A+pilot+study%5BTitle%5D)+AND+%22Pain+Physician%22%5BJournal%5D)">Green light-based analgesia - novel non-pharmacological approach to fibromyalgia pain: A pilot study.</a> Pain Physician. 26 (4), 403-410 (2023).</li>
<li>Martin, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((light+exposure+improves+pain+and+quality+of+life+in+fibromyalgia+patients%3A+A+preliminary+one-way+crossover+clinical+trial%5BTitle%5D)+AND+%22Pain+Med%22%5BJournal%5D)">light exposure improves pain and quality of life in fibromyalgia patients: A preliminary one-way crossover clinical trial.</a> Pain Med. 22 (1), 118-130 (2021).</li>
<li>Qaiser, H., Uzair, M., Arshad, M., Zafar, A., Bashir, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Evaluating+the+potential+of+green+light+exposure+on+nociception-A+mini+review%5BTitle%5D)+AND+%22CNS+Neurol+Disord+Drug+Targets%22%5BJournal%5D)">Evaluating the potential of green light exposure on nociception-A mini review.</a> CNS Neurol Disord Drug Targets. 23 (6), 675-679 (2024).</li>
<li>Lipton, R. B., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Narrow+band+green+light+effects+on+headache%2C+photophobia%2C+sleep%2C+and+anxiety+among+migraine+patients%3A+an+open-label+study+conducted+online+using+daily+headache+diary%5BTitle%5D)+AND+%22Front+Neurol%22%5BJournal%5D)">Narrow band green light effects on headache, photophobia, sleep, and anxiety among migraine patients: an open-label study conducted online using daily headache diary.</a> Front Neurol. 14, 1282236(2023).</li>
<li>Posternack, C., Kupchak, P., Capriolo, A. I., Katz, B. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Targeting+the+intrinsically+photosensitive+retinal+ganglion+cell+to+reduce+headache+pain+and+light+sensitivity+in+migraine%3A+A+randomized+double-blind+trial%5BTitle%5D)+AND+%22J+Clin+Neurosci%22%5BJournal%5D)">Targeting the intrinsically photosensitive retinal ganglion cell to reduce headache pain and light sensitivity in migraine: A randomized double-blind trial.</a> J Clin Neurosci. 113, 22-31 (2023).</li>
<li>Noseda, R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Migraine+photophobia+originating+in+cone-driven+retinal+pathways%5BTitle%5D)+AND+%22Brain%22%5BJournal%5D)">Migraine photophobia originating in cone-driven retinal pathways.</a> Brain. 139 (7), 1971-1986 (2016).</li>
<li>Ibrahim, M. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Long-lasting+antinociceptive+effects+of+green+light+in+acute+and+chronic+pain+in+rats%5BTitle%5D)+AND+%22Pain%22%5BJournal%5D)">Long-lasting antinociceptive effects of green light in acute and chronic pain in rats.</a> Pain. 158 (2), 347-360 (2017).</li>
<li>Martin, L. F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((light+exposure+elicits+anti-inflammation%2C+endogenous+opioid+release+and+dampens+synaptic+potentiation+to+relieve+post-surgical+pain%5BTitle%5D)+AND+%22J+Pain%22%5BJournal%5D)">light exposure elicits anti-inflammation, endogenous opioid release and dampens synaptic potentiation to relieve post-surgical pain.</a> J Pain. 24 (3), 509-529 (2023).</li>
<li>Tang, Y. L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Green+light+analgesia+in+mice+is+mediated+by+visual+activation+of+enkephalinergic+neurons+in+the+ventrolateral+geniculate+nucleus%5BTitle%5D)+AND+%22Sci+Transl+Med%22%5BJournal%5D)">Green light analgesia in mice is mediated by visual activation of enkephalinergic neurons in the ventrolateral geniculate nucleus.</a> Sci Transl Med. 14 (674), eabq6474(2022).</li>
<li>Cao, P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((light+induces+antinociception+via+visual-somatosensory+circuits%5BTitle%5D)+AND+%22Cell+Rep%22%5BJournal%5D)">light induces antinociception via visual-somatosensory circuits.</a> Cell Rep. 42 (4), 112290(2023).</li>
<li>Wu, X. Q., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Glutamatergic+and+GABAergic+neurons+in+the+vLGN+mediate+the+nociceptive+effects+of+green+and+red+light+on+neuropathic+pain%5BTitle%5D)+AND+%22Neurobiol+Dis%22%5BJournal%5D)">Glutamatergic and GABAergic neurons in the vLGN mediate the nociceptive effects of green and red light on neuropathic pain.</a> Neurobiol Dis. 183, 106164(2023).</li>
<li>Sprenger, C., Eichler, I. C., Eichler, L., Zöllner, C., Büchel, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Altered+signaling+in+the+descending+pain-modulatory+system+after+short-term+infusion+of+the+%C2%B5-opioid+agonist+remifentanil%5BTitle%5D)+AND+%22J+Neurosci%22%5BJournal%5D)">Altered signaling in the descending pain-modulatory system after short-term infusion of the µ-opioid agonist remifentanil.</a> J Neurosci. 38 (10), 2454-2470 (2018).</li>
<li>Zahn, P. K., Brennan, T. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Primary+and+secondary+hyperalgesia+in+a+rat+model+for+human+postoperative+pain%5BTitle%5D)+AND+%22Anesthesiology%22%5BJournal%5D)">Primary and secondary hyperalgesia in a rat model for human postoperative pain.</a> Anesthesiology. 90 (3), 863-872 (1999).</li>
<li>Brennan, T. J., Zahn, P. K., Pogatzki-Zahn, E. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mechanisms+of+incisional+pain%5BTitle%5D)+AND+%22Anesthesiol+Clin+North+Am%22%5BJournal%5D)">Mechanisms of incisional pain.</a> Anesthesiol Clin North Am. 23 (1), 1-20 (2005).</li>
<li>Martin, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Conotoxin+contulakin-G+engages+a+neurotensin+receptor+2%2FR-type+calcium+channel+%28Cav2.3%29+pathway+to+mediate+spinal+antinociception%5BTitle%5D)+AND+%22Pain%22%5BJournal%5D)">Conotoxin contulakin-G engages a neurotensin receptor 2/R-type calcium channel (Cav2.3) pathway to mediate spinal antinociception.</a> Pain. 163 (9), 1751-1762 (2022).</li>
<li>Korah, H. E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Partial+sciatic+nerve+ligation%3A+A+mouse+model+of+chronic+neuropathic+pain+to+study+the+antinociceptive+effect+of+novel+therapies%5BTitle%5D)+AND+%22J+VIs+Exp%22%5BJournal%5D)">Partial sciatic nerve ligation: A mouse model of chronic neuropathic pain to study the antinociceptive effect of novel therapies.</a> J VIs Exp. (188), e64555(2022).</li>
<li>Chaplan, S. R., Bach, F. W., Pogrel, J. W., Chung, J. M., Yaksh, T. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Quantitative+assessment+of+tactile+allodynia+in+the+rat+paw%5BTitle%5D)+AND+%22J+Neurosci+Methods%22%5BJournal%5D)">Quantitative assessment of tactile allodynia in the rat paw.</a> J Neurosci Methods. 53 (1), 55-63 (1994).</li>
<li>Lockwood, S., Dickenson, A. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((What+goes+up+must+come+down%3A+insights+from+studies+on+descending+controls+acting+on+spinal+pain+processing%5BTitle%5D)+AND+%22J+Neural+Transm+%28Vienna%29%22%5BJournal%5D)">What goes up must come down: insights from studies on descending controls acting on spinal pain processing.</a> J Neural Transm (Vienna). 127 (4), 541-549 (2020).</li>
<li>Staud, R., Robinson, M. E., Price, D. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Temporal+summation+of+second+pain+and+its+maintenance+are+useful+for+characterizing+widespread+central+sensitization+of+fibromyalgia+patients%5BTitle%5D)+AND+%22J+Pain%22%5BJournal%5D)">Temporal summation of second pain and its maintenance are useful for characterizing widespread central sensitization of fibromyalgia patients.</a> J Pain. 8 (11), 893-901 (2007).</li>
<li>Ventura, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((light+exposure+reduces+primary+hyperalgesia+and+proinflammatory+cytokines+in+a+rodent+model+of+knee+osteoarthritis%3A+Shedding+light+on+sex+differences%5BTitle%5D)+AND+%22Biomedicines%22%5BJournal%5D)">light exposure reduces primary hyperalgesia and proinflammatory cytokines in a rodent model of knee osteoarthritis: Shedding light on sex differences.</a> Biomedicines. 12 (9), 2005(2024).</li>
<li>Cheng, K., Martin, L. F., Slepian, M. J., Patwardhan, A. M., Ibrahim, M. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mechanisms+and+pathways+of+pain+photobiomodulation%3A+A+narrative+review%5BTitle%5D)+AND+%22J+Pain%22%5BJournal%5D)">Mechanisms and pathways of pain photobiomodulation: A narrative review.</a> J Pain. 22 (7), 763-777 (2021).</li>
<li>Cheng, K., Martin, L. F., Calligaro, H., Patwardhan, A., Ibrahim, M. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Case+report%3A+Green+light+exposure+relieves+chronic+headache+pain+in+a+colorblind+patient%5BTitle%5D)+AND+%22Clin+Med+Insights+Case+Rep%22%5BJournal%5D)">Case report: Green light exposure relieves chronic headache pain in a colorblind patient.</a> Clin Med Insights Case Rep. 15, 11795476221125164(2022).</li>
<li>Takemura, Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effects+of+green+color+exposure+on+stress%2C+anxiety%2C+and+pain+during+peripheral+intravenous+cannulation+in+dental+patients+requiring+sedation%5BTitle%5D)+AND+%22Int+J+Environ+Res+Public+Health%22%5BJournal%5D)">Effects of green color exposure on stress, anxiety, and pain during peripheral intravenous cannulation in dental patients requiring sedation.</a> Int J Environ Res Public Health. 18 (11), 5939(2021).</li>
<li>Berkley, K. J., Hubscher, C. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Are+there+separate+central+nervous+system+pathways+for+touch+and+pain%5BTitle%5D)+AND+%22Nat+Med%22%5BJournal%5D)">Are there separate central nervous system pathways for touch and pain.</a> Nat Med. 1 (8), 766-773 (1995).</li>
<li>Bannister, K., Kucharczyk, M. W., Graven-Nielsen, T., Porreca, F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Introducing+descending+control+of+nociception%3A+a+measure+of+diffuse+noxious+inhibitory+controls+in+conscious+animals%5BTitle%5D)+AND+%22Pain%22%5BJournal%5D)">Introducing descending control of nociception: a measure of diffuse noxious inhibitory controls in conscious animals.</a> Pain. 162 (7), 1957-1959 (2021).</li>
<li>Millan, M. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Descending+control+of+pain%5BTitle%5D)+AND+%22Prog+Neurobiol%22%5BJournal%5D)">Descending control of pain.</a> Prog Neurobiol. 66 (6), 355-474 (2002).</li>
<li>Ossipov, M. H., Morimura, K., Porreca, F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Descending+pain+modulation+and+chronification+of+pain%5BTitle%5D)+AND+%22Curr+Opin+Support+Palliat+Care%22%5BJournal%5D)">Descending pain modulation and chronification of pain.</a> Curr Opin Support Palliat Care. 8 (2), 143-151 (2014).</li>
</ol>

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optimalisatie van fotoneuromodulatietechnieken om de rol van groen lichtgevende diodes bij pijnbestrijding te evalueren

Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management

Optimalisatie van fotoneuromodulatietechnieken om de rol van groen lichtgevende diodes bij pijnbestrijding te evalueren

Despite extensive research and the identification of numerous analgesic targets, the range of pharmacological treatments available for pain remains ...

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Volwassen geboren neuronen die ChR2 kunnen worden gemanipuleerd in slice elektrofysiologische voorbereidingen om hun bijdrage aan de functie van olfactorische neurale circuits te onderzoeken.

Met behulp van betaalbare LED-arrays voor Photo-stimulatie van neuronen

Volwassen geboren neuronen van de bulbus olfactorius kan optogenetically worden gecontroleerd met behulp van Channelrhodopsin2 expressie lentivirale injectie in de rostrale migratie stroom en chronische fotostimulering met een geïmplanteerd miniatuur LED.

Selectieve Viral Transductie van Adult geboren Olfactorische Neuronen voor chronische In vivo Optogenetic Stimulatie

Source: Zhang, L., et al. Near Infrared (NIr) Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium. J. Vis. Exp. (2015)This video demonstrates the process of applying NIr light to a shaved mouse scalp to activate vestibular neurons and stimulate superoxide dismutase-1 (SOD-1) production, supporting neuronal function. The procedure highlights NIr therapy as a neuroprotective strategy.

Modulating Sensory Neuronal Signaling in a Mouse Model Using Near Infrared Light

Optogenetica is een krachtig hulpmiddel geworden voor gebruik in gedragsneurowetenschappelijke experimenten. Dit protocol biedt een stapsgewijze handleiding voor het ontwerp en de installatie van lasersystemen en biedt een volledig protocol voor het uitvoeren van meerdere en gelijktijdige in vivo optogenetische stimulaties die compatibel zijn met de meeste gedragstestparadigma's bij knaagdieren.

In vivo optogenetische Stimulatie van de knaagdieren centrale zenuwstelsel

Niet-coherent xenonlicht werd door smalbandige interferentie en neutrale dichtheidsfilters geleid om licht met verschillende golflengten en intensiteit aan gekweekte cellen te leveren. Dit protocol werd gebruikt om de effecten van rood/nabij-infrarood lichttherapie op de productie van reactieve soorten in vitro te beoordelen: er werden geen effecten waargenomen met de geteste parameters.

Methode voor de evaluatie van de effecten van een golflengtebereik en intensiteiten van Rood / nabij-infrarood Lichttherapie op oxidatieve stress In Vitro

Dit protocol beschrijft hoe de tijdelijke verwarming die geassocieerd is met de optische absorptie van gouden nanostaafjes, kan worden gebruikt om differentiatie en intracellulaire calciumactiviteit in neuronale cellen te stimuleren. Deze resultaten openen mogelijk nieuwe toepassingen in neurale prothesen en fundamentele studies in de neurowetenschappen.

Goud nanorod-bijgestaan ​​Optische Stimulatie van neuronale cellen

Een methode voor stimulatie van in-vitro celcultuur elektrische activiteit met zichtbaar licht, gebaseerd op het gebruik van organische halfgeleidende polymeren, wordt beschreven.

Optische controle van levende cellen elektrische activiteit van geconjugeerde polymeren

Hier presenteren we de fabricagemethode van een optrode-systeem met optische vezels voor lichtafgifte en een elektrode-array voor neurale opname. In vivo experimenten met transgene muizen die channelrhodopsine-2 tot expressie brengen, tonen de haalbaarheid van het systeem voor gelijktijdige optogenetische stimulatie en elektrofysiologische registratie.

Optrode Array voor gelijktijdige optogenetische modulatie en elektrische neurale opname

Hier beschrijven we een nieuw, eenvoudig en goedkoop apparaat om met succes in vitro fotodynamische therapie (PDT) -testen uit te voeren met behulp van tweedimensionale HeLa-celcultuur en verteporfine als een fotosensitizer.

Een in-house gebouwd en licht-emitting-diode-gebaseerd fotodynamisch therapie-apparaat voor het verbeteren van verteporfine cytotoxiciteit in een 2D-celcultuurmodel

Deze studie presenteert de niet-invasieve en draagbare technologie van transcraniële fotobiomodulatie onder elektro-encefalografische controle voor stimulatie van lymfatische verwijdering van toxines (bijv. Oplosbaar bèta-amyloïde) uit de hersenen van verouderde en niet-verdoofde BALB/c mannelijke muizen tijdens natuurlijke diepe slaap.

Fotobiomodulatie onder elektro-encefalografische controles van slaap voor stimulatie van lymfatische verwijdering van gifstoffen uit de hersenen van muizen

Hier presenteren we een methode voor het beoordelen van de activatie en blokkade van sensorische axonen in perifere zenuwen in acute, onder narcose en in vivo ratexperimenten met behulp van twee soorten spinale elektrofysiologische metingen die de activiteit van zenuwvezelsubtypes kunnen onderscheiden: Local Field Potentials en Wide Dynamic Range single-neuron opnames.

Elektrofysiologische methoden om perifere pijnblokkade bij een verdoofde rat te beoordelen

Leer fotoneuromodulatie met groene LED voor pijnbestrijding bij ratten en mensen. Deze methode optimaliseert belichtingsparameters van 525 nm voor consistente toepassing in acute en chronische pijn.

Optimalisatie van fotoneuromodulatietechnieken om de rol van groen lichtgevende diodes bij pijnbestrijding te evalueren

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