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<ol><li>Ford, J. L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Use+of+Model-Based+Compartmental+Analysis+and+a+Super-Child+Design+to+Study+Whole-Body+Retinol+Kinetics+and+Vitamin+A+Total+Body+Stores+in+Children+from+3+Lower-Income+Countries%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Use of Model-Based Compartmental Analysis and a Super-Child Design to Study Whole-Body Retinol Kinetics and Vitamin A Total Body Stores in Children from 3 Lower-Income Countries.</a> J Nutr. 150 (2), 411-418 (2020).</li>
<li>Haskell, M. J., Jamil, K. M., Peerson, J. M., Wahed, M. A., Brown, K. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+paired+deuterated+retinol+dilution+technique+can+be+used+to+estimate+the+daily+vitamin+A+intake+required+to+maintain+a+targeted+whole+body+vitamin+A+pool+size+in+men%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">The paired deuterated retinol dilution technique can be used to estimate the daily vitamin A intake required to maintain a targeted whole body vitamin A pool size in men.</a> J Nutr. 141 (3), 428-432 (2011).</li>
<li>Lietz, G., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Current+Capabilities+and+Limitations+of+Stable+Isotope+Techniques+and+Applied+Mathematical+Equations+in+Determining+Whole-Body+Vitamin+A+Status%5BTitle%5D)+AND+%22Food+Nutr+Bull%22%5BJournal%5D)">Current Capabilities and Limitations of Stable Isotope Techniques and Applied Mathematical Equations in Determining Whole-Body Vitamin A Status.</a> Food Nutr Bull. 37, S87-S103 (2016).</li>
<li>Pinkaew, S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Triple-Fortified+Rice+Containing+Vitamin+A+Reduced+Marginal+Vitamin+A+Deficiency+and+Increased+Vitamin+A+Liver+Stores+in+School-Aged+Thai+Children%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Triple-Fortified Rice Containing Vitamin A Reduced Marginal Vitamin A Deficiency and Increased Vitamin A Liver Stores in School-Aged Thai Children.</a> J Nutr. 144 (4), 519-524 (2014).</li>
<li>VMNIS: Serum retinol concentrations for determining the prevalence of vitamin A deficiency in populations. , World Health Organisation. 
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<li>Engle-Stone, R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Plasma+retinol-binding+protein+predicts+plasma+retinol+concentration+in+both+infected+and+uninfected+Cameroonian+women+and+children%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Plasma retinol-binding protein predicts plasma retinol concentration in both infected and uninfected Cameroonian women and children.</a> J Nutr. 141 (12), 2233-2241 (2011).</li>
<li>Engle-Stone, R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Filipino+Children+with+High+Usual+Vitamin+A+Intakes+and+Exposure+to+Multiple+Sources+of+Vitamin+A+Have+Elevated+Total+Body+Stores+of+Vitamin+A+But+Do+Not+Show+Clear+Evidence+of+Vitamin+A+Toxicity%5BTitle%5D)+AND+%22Curr+Dev+Nutr%22%5BJournal%5D)">Filipino Children with High Usual Vitamin A Intakes and Exposure to Multiple Sources of Vitamin A Have Elevated Total Body Stores of Vitamin A But Do Not Show Clear Evidence of Vitamin A Toxicity.</a> Curr Dev Nutr. 6 (8), nzac115(2022).</li>
<li>Larson, L. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Approaches+to+Assess+Vitamin+A+Status+in+Settings+of+Inflammation%3A+Biomarkers+Reflecting+Inflammation+and+Nutritional+Determinants+of+Anemia+%28BRINDA%29+Project%5BTitle%5D)+AND+%22Nutrients%22%5BJournal%5D)">Approaches to Assess Vitamin A Status in Settings of Inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) Project.</a> Nutrients. 10 (8), (2018).</li>
<li>Sheftel, J., Tanumihardjo, S. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Systematic+Review+and+Meta-Analysis+of+the+Relative+Dose-Response+Tests+to+Assess+Vitamin+A+Status%5BTitle%5D)+AND+%22Adv+Nutr%22%5BJournal%5D)">Systematic Review and Meta-Analysis of the Relative Dose-Response Tests to Assess Vitamin A Status.</a> Adv Nutr. 12 (3), 904-941 (2021).</li>
<li>Tanumihardjo, S. A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Biomarkers+of+Nutrition+for+Development+%28BOND%29-Vitamin+A+Review%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Biomarkers of Nutrition for Development (BOND)-Vitamin A Review.</a> J Nutr. 146 (9), 1816-1848 (2016).</li>
<li>Furr, H. C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Vitamin+A+concentrations+in+liver+determined+by+isotope+dilution+assay+with+tetradeuterated+vitamin+A+and+by+biopsy+in+generally+healthy+adult+humans%5BTitle%5D)+AND+%22Am+J+Clin+Nutr%22%5BJournal%5D)">Vitamin A concentrations in liver determined by isotope dilution assay with tetradeuterated vitamin A and by biopsy in generally healthy adult humans.</a> Am J Clin Nutr. 49 (4), 713-716 (1989).</li>
<li>Haskell, M. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Assessment+of+vitamin+A+status+by+the+deuterated-retinol-dilution+technique+and+comparison+with+hepatic+vitamin+A+concentration+in+Bangladeshi+surgical+patients%5BTitle%5D)+AND+%22Am+J+Clin+Nutr%22%5BJournal%5D)">Assessment of vitamin A status by the deuterated-retinol-dilution technique and comparison with hepatic vitamin A concentration in Bangladeshi surgical patients.</a> Am J Clin Nutr. 66 (1), 67-74 (1997).</li>
<li>Green, M. H., Ford, J. L., Green, J. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Development+of+a+Compartmental+Model+to+Investigate+the+Influence+of+Inflammation+on+Predictions+of+Vitamin+A+Total+Body+Stores+by+Retinol+Isotope+Dilution+in+Theoretical+Humans%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Development of a Compartmental Model to Investigate the Influence of Inflammation on Predictions of Vitamin A Total Body Stores by Retinol Isotope Dilution in Theoretical Humans.</a> J Nutr. 151 (3), 731-741 (2021).</li>
<li>Suri, D. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Association+between+Biomarkers+of+Inflammation+and+Total+Liver+Vitamin+A+Reserves+Estimated+by+%2813%29C-Retinol+Isotope+Dilution+among+Preschool+Children+in+5+African+Countries%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Association between Biomarkers of Inflammation and Total Liver Vitamin A Reserves Estimated by (13)C-Retinol Isotope Dilution among Preschool Children in 5 African Countries.</a> J Nutr. 153 (13), 622-635 (2023).</li>
<li>Furr, H. C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Stable+isotope+dilution+techniques+for+assessing+vitamin+A+status+and+bioefficacy+of+provitamin+A+carotenoids+in+humans%5BTitle%5D)+AND+%22Public+Health+Nutr%22%5BJournal%5D)">Stable isotope dilution techniques for assessing vitamin A status and bioefficacy of provitamin A carotenoids in humans.</a> Public Health Nutr. 8 (6), 596-607 (2005).</li>
<li>Green, M. H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+Retinol+Isotope+Dilution+Equation+Predicts+Both+Group+and+Individual+Total+Body+Vitamin+A+Stores+in+Adults+Based+on+Data+from+an+Early+Postdosing+Blood+Sample%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">A Retinol Isotope Dilution Equation Predicts Both Group and Individual Total Body Vitamin A Stores in Adults Based on Data from an Early Postdosing Blood Sample.</a> J Nutr. 146 (10), 2137-2142 (2016).</li>
<li>Green, M. H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Use+of+Population-Based+Compartmental+Modeling+and+Retinol+Isotope+Dilution+to+Study+Vitamin+A+Kinetics+and+Total+Body+Stores+among+Ghanaian+Women+of+Reproductive+Age%5BTitle%5D)+AND+%22Curr+Dev+Nutr%22%5BJournal%5D)">Use of Population-Based Compartmental Modeling and Retinol Isotope Dilution to Study Vitamin A Kinetics and Total Body Stores among Ghanaian Women of Reproductive Age.</a> Curr Dev Nutr. 8 (11), 104484(2024).</li>
<li>Haskell, M. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Population-based+plasma+kinetics+of+an+oral+dose+of+%5B2H4%5Dretinyl+acetate+among+preschool-aged%2C+Peruvian+children%5BTitle%5D)+AND+%22Am+J+Clin+Nutr%22%5BJournal%5D)">Population-based plasma kinetics of an oral dose of [2H4]retinyl acetate among preschool-aged, Peruvian children.</a> Am J Clin Nutr. 77 (3), 681-686 (2003).</li>
<li>Lopez-Teros, V., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Use+of+a+%26%2334%3BSuper-child%27%27+Approach+to+Assess+the+Vitamin+A+Equivalence+of+Moringa+oleifera+Leaves%2C+Develop+a+Compartmental+Model+for+Vitamin+A+Kinetics%2C+and+Estimate+Vitamin+A+Total+Body+Stores+in+Young+Mexican+Children%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Use of a &#34;Super-child'' Approach to Assess the Vitamin A Equivalence of Moringa oleifera Leaves, Develop a Compartmental Model for Vitamin A Kinetics, and Estimate Vitamin A Total Body Stores in Young Mexican Children.</a> J Nutr. 147 (12), 2356-2363 (2017).</li>
<li>Oxley, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((An+LC%2FMS%2FMS+method+for+stable+isotope+dilution+studies+of+beta-carotene+bioavailability%2C+bioconversion%2C+and+vitamin+A+status+in+humans%5BTitle%5D)+AND+%22J+Lipid+Res%22%5BJournal%5D)">An LC/MS/MS method for stable isotope dilution studies of beta-carotene bioavailability, bioconversion, and vitamin A status in humans.</a> J Lipid Res. 55 (2), 319-328 (2014).</li>
<li>Ribaya-Mercado, J. D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Quantitative+assessment+of+total+body+stores+of+vitamin+A+in+adults+with+the+use+of+a+3-d+deuterated-retinol-dilution+procedure%5BTitle%5D)+AND+%22Am+J+Clin+Nutr%22%5BJournal%5D)">Quantitative assessment of total body stores of vitamin A in adults with the use of a 3-d deuterated-retinol-dilution procedure.</a> Am J Clin Nutr. 77 (3), 694-699 (2003).</li>
<li>Tang, G. W., Qin, J., Hao, L. Y., Yin, S. A., Russell, R. M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Use+of+a+short-term+isotope-dilution+method+for+determining+the+vitamin+A+status+of+children%5BTitle%5D)+AND+%22Am+J+Clin+Nutr%22%5BJournal%5D)">Use of a short-term isotope-dilution method for determining the vitamin A status of children.</a> Am J Clin Nutr. 76 (2), 413-418 (2002).</li>
<li>Oxley, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Determination+of+Vitamin+A+Total+Body+Stores+in+Children+from+Dried+Serum+Spots%3A+Application+in+a+Low-+and+Middle-Income+Country+Community+Setting%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Determination of Vitamin A Total Body Stores in Children from Dried Serum Spots: Application in a Low- and Middle-Income Country Community Setting.</a> J Nutr. 151 (5), 1341-1346 (2021).</li>
<li>Oxley, A., Lietz, G. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Use+of+stable+isotopes+to+study+bioconversion+and+bioefficacy+of+provitamin+A+carotenoids%5BTitle%5D)+AND+%22Methods+Enzymol%22%5BJournal%5D)">Use of stable isotopes to study bioconversion and bioefficacy of provitamin A carotenoids.</a> Methods Enzymol. 670, 399-422 (2022).</li>
<li>Preston, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Existing+and+emerging+technologies+for+measuring+stable+isotope+labelled+retinol+in+biological+samples%3A+isotope+dilution+analysis+of+body+retinol+stores%5BTitle%5D)+AND+%22Int+J+Vitam+Nutr+Res%22%5BJournal%5D)">Existing and emerging technologies for measuring stable isotope labelled retinol in biological samples: isotope dilution analysis of body retinol stores.</a> Int J Vitam Nutr Res. 84 (Suppl 1), 30-39 (2014).</li>
<li>Tang, G. W., Qin, J., Dolnikowski, G. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Deuterium+enrichment+of+retinol+in+humans+determined+by+gas+chromatography+electron+capture+negative+chemical+ionization+mass+spectrometry%5BTitle%5D)+AND+%22J+Nutr+Biochem%22%5BJournal%5D)">Deuterium enrichment of retinol in humans determined by gas chromatography electron capture negative chemical ionization mass spectrometry.</a> J Nutr Biochem. 9 (7), 408-414 (1998).</li>
<li>Wang, J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Vitamin+A+equivalence+of+spirulina+beta-carotene+in+Chinese+adults+as+assessed+by+using+a+stable-isotope+reference+method%5BTitle%5D)+AND+%22Am+J+Clin+Nutr%22%5BJournal%5D)">Vitamin A equivalence of spirulina beta-carotene in Chinese adults as assessed by using a stable-isotope reference method.</a> Am J Clin Nutr. 87 (6), 1730-1737 (2008).</li>
<li>Gannon, B., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Biofortified+orange+maize+is+as+efficacious+as+a+vitamin+A+supplement+in+Zambian+children+even+in+the+presence+of+high+liver+reserves+of+vitamin+A%3A+a+community-based%2C+randomized+placebo-controlled+trial%5BTitle%5D)+AND+%22Am+J+Clin+Nutr%22%5BJournal%5D)">Biofortified orange maize is as efficacious as a vitamin A supplement in Zambian children even in the presence of high liver reserves of vitamin A: a community-based, randomized placebo-controlled trial.</a> Am J Clin Nutr. 100 (6), 1541-1550 (2014).</li>
<li>Green, M. H., Lopez-Teros, V., Green, J. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Does+the+Amount+of+Stable+Isotope+Dose+Influence+Retinol+Kinetic+Responses+and+Predictions+of+Vitamin+A+Total+Body+Stores+by+the+Retinol+Isotope+Dilution+Method+in+Theoretical+Children+and+Adults%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Does the Amount of Stable Isotope Dose Influence Retinol Kinetic Responses and Predictions of Vitamin A Total Body Stores by the Retinol Isotope Dilution Method in Theoretical Children and Adults.</a> J Nutr. 152 (1), 86-93 (2022).</li>
<li>Ribaya-Mercado, J. D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Bioconversion+of+plant+carotenoids+to+vitamin+A+in+Filipino+school-age+children+varies+inversely+with+vitamin+A+status%5BTitle%5D)+AND+%22Faseb+J%22%5BJournal%5D)">Bioconversion of plant carotenoids to vitamin A in Filipino school-age children varies inversely with vitamin A status.</a> Faseb J. 14 (4), A486-A486 (2000).</li>
<li>Valentine, A. R., Davis, C. R., Tanumihardjo, S. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Vitamin+A+isotope+dilution+predicts+liver+stores+in+line+with+long-term+vitamin+A+intake+above+the+current+Recommended+Dietary+Allowance+for+young+adult+women%5BTitle%5D)+AND+%22Am+J+Clin+Nutr%22%5BJournal%5D)">Vitamin A isotope dilution predicts liver stores in line with long-term vitamin A intake above the current Recommended Dietary Allowance for young adult women.</a> Am J Clin Nutr. 98 (5), 1192-1199 (2013).</li>
<li>Hemery, Y. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Influence+of+light+exposure+and+oxidative+status+on+the+stability+of+vitamins+A+and+D3+during+the+storage+of+fortified+soybean+oil%5BTitle%5D)+AND+%22Food+Chem%22%5BJournal%5D)">Influence of light exposure and oxidative status on the stability of vitamins A and D3 during the storage of fortified soybean oil.</a> Food Chem. 184, 90-98 (2015).</li>
<li>Shahidi, F., de Camargo, A. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Tocopherols+and+Tocotrienols+in+Common+and+Emerging+Dietary+Sources%3A+Occurrence%2C+Applications%2C+and+Health+Benefits%5BTitle%5D)+AND+%22Int+J+Mol+Sci%22%5BJournal%5D)">Tocopherols and Tocotrienols in Common and Emerging Dietary Sources: Occurrence, Applications, and Health Benefits.</a> Int J Mol Sci. 17 (10), (2016).</li>
<li>Liu, Z., Lee, H. J., Garofalo, F., Jenkins, D. J. A., El-Sohemy, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Simultaneous+Measurement+of+Three+Tocopherols%2C+All-trans-retinol%2C+and+Eight+Carotenoids+in+Human+Plasma+by+Isocratic+Liquid+Chromatography%5BTitle%5D)+AND+%22J+Chromatograph+Sci%22%5BJournal%5D)">Simultaneous Measurement of Three Tocopherols, All-trans-retinol, and Eight Carotenoids in Human Plasma by Isocratic Liquid Chromatography.</a> J Chromatograph Sci. 49 (3), 221-227 (2011).</li>
<li>Davies, P. S. W. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Stable+isotopes%3A+their+use+and+safety+in+human+nutrition+studies%5BTitle%5D)+AND+%22Eur+J+Clin+Nutr%22%5BJournal%5D)">Stable isotopes: their use and safety in human nutrition studies.</a> Eur J Clin Nutr. 74 (3), 362-365 (2020).</li>
<li>Haskell, M. J., Ribaya-Mercado, J. D. <a target="_blank" href="http://scholar.google.com/scholar?hl=en&safe=off&q=author%3aHaskell%2C+MJ+%22Handbook+on+Vitamin+A+Tracer+Dilution+Methods+to+Assess+Status+and+Evaluate+Intervention+Programs%22">Handbook on Vitamin A Tracer Dilution Methods to Assess Status and Evaluate Intervention Programs</a>. , Harvest Plus Technical Monographs. (2005).</li>
<li>Han, S. H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Quantitative+characterization+of+degradation+behaviors+of+antioxidants+stabilized+in+lipid+particles%5BTitle%5D)+AND+%22Talanta%22%5BJournal%5D)">Quantitative characterization of degradation behaviors of antioxidants stabilized in lipid particles.</a> Talanta. 71 (5), 2129-2133 (2007).</li>
<li>Park, H., Mun, S., Kim, Y. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((UV+and+storage+stability+of+retinol+contained+in+oil-in-water+nanoemulsions%5BTitle%5D)+AND+%22Food+Chem%22%5BJournal%5D)">UV and storage stability of retinol contained in oil-in-water nanoemulsions.</a> Food Chem. 272, 404-410 (2019).</li>
<li>Retinol 50C, 15D and 10S. , BASF. 
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<li>Green, M. H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Plasma+Retinol+Kinetics+and+beta-Carotene+Bioefficacy+Are+Quantified+by+Model-Based+Compartmental+Analysis+in+Healthy+Young+Adults+with+Low+Vitamin+A+Stores%5BTitle%5D)+AND+%22J+Nutr%22%5BJournal%5D)">Plasma Retinol Kinetics and beta-Carotene Bioefficacy Are Quantified by Model-Based Compartmental Analysis in Healthy Young Adults with Low Vitamin A Stores.</a> J Nutr. 146 (10), 2129-2136 (2016).</li>
</ol>

<table><tbody><tr><td>2ml barnstenen glazen injectieflacons voor het verdelen van doses</td><td>Fisher</td><td>11573690</td><td>Afhankelijk van de monsterschaal van het onderzoek en het aantal vrijwilligers dat dagelijks wordt gedoseerd, kan het efficiënter zijn om grotere, bijv. 4ml, barnstenen injectieflacons te gebruiken</td></tr><tr><td>100ml volumetrische kolven</td><td>Fisher</td><td>11323644</td><td>Pyrex Borosilicaat Glas Klasse A Gecertificeerde Volumetrische Kolf</td></tr><tr><td>50ml volumetrische kolven</td><td>Fisher</td><td>11313644</td><td>Pyrex Borosilicaat Glas Klasse A Gecertificeerde Volumetrische Kolf</td></tr><tr><td>Analytische weegschalen&nbsp;</td><td>Fisher</td><td>13592970</td><td></td></tr><tr><td>Capillaire plunjerpompen (pipettips) CP100 10x96 TIPACK</td><td>Gilson</td><td>FD148314</td><td></td></tr><tr><td>Capillaire plunjerpompen CP1000ST 2x91</td><td>Gilson</td><td>F148180</td><td></td></tr><tr><td>Capillaire plunjerpompen CP250ST 6x96</td><td>Gilson</td><td>F148714</td><td></td></tr><tr><td>Karton cryobox</td><td>Starlab</td><td>A9623-8181</td><td></td></tr><tr><td>Hellma cuvet UV kwarts</td><td>SLS</td><td>CEL1600</td><td></td></tr><tr><td>Hexaan 95% n-Hexaan voor HPLC Gecertificeerd HPLC</td><td>Fisher</td><td>H/0406/17</td><td></td></tr><tr><td>Decklidjes voor 2ml barnstenen glazen injectieflacons</td><td>Fisher</td><td>11573542</td><td></td></tr><tr><td>Microman E M1000E Pipet (positieve verplaatsing)</td><td>Gilson</td><td>FD10006</td><td></td></tr><tr><td>Microman E M100E Pipet (positieve verplaatsing)</td><td>Gilson</td><td>FD10004</td><td></td></tr><tr><td>Microman E M250E Pipet (positieve verplaatsing)</td><td>Gilson</td><td>FD10005</td><td></td></tr><tr><td>Microscoop</td><td>Nikon</td><td>Eclipse E400</td><td></td></tr><tr><td>Microscoop glazen slides&nbsp;</td><td>Sigma</td><td>41122601</td><td></td></tr><tr><td>Sonicerende waterbad</td><td>VWR</td><td>USC100T</td><td></td></tr><tr><td>Spectrofotometer</td><td>Thermo Fisher Scientific</td><td>A51119600C</td><td></td></tr><tr><td>Stabiel isotoop gelabelde retinylacetaat tracer</td><td>Buchem BV</td><td>N/A</td><td>Een reeks stabiele isotopen kan worden gebruikt voor de RID-methode. Een lijst van verschillende commercieel verkrijgbare isotopen wordt gegeven in Tabel 1.&nbsp;</td></tr><tr><td>Ongeroerde waterbad</td><td>SLS</td><td>SLS1176</td><td></td></tr><tr><td>Plantaardige olie</td><td>Elke supermarkt</td><td>N/A</td><td>Het is belangrijk om verse plantaardige olie met voldoende houdbaarheid te gebruiken voor het bereiden van isotoopdoses.</td></tr><tr><td>Volac ongeplugde glazen pasteurpipet 150mm</td><td>SLS</td><td>PIP4150</td><td></td></tr></tbody></table>

formulering van vitamine a-tracerdoses voor toediening aan menselijke proefpersonen met behulp van de retinolisotoopverdunningstechniek

Formulation of Vitamin A Tracer Doses for Administration to Human Subjects using Retinol Isotope Dilution Technique

Formulering van vitamine A-tracerdoses voor toediening aan menselijke proefpersonen met behulp van de retinolisotoopverdunningstechniek

The retinol isotope dilution (RID) technique relies on the administration of isotopically labeled vitamin A tracers to human subjects. Here, we present a ...

formulation-vitamin-tracer-doses-for-administration-to-human-subjects

Research

JoVE Journal

Biochemistry

Biochemie

Hier wordt een normale-fase, high-performance vloeistofchromatografiemethode beschreven om kritische retinoïden te detecteren en te kwantificeren die betrokken zijn bij het vergemakkelijken van de visuele functie in zowel oog- als systemisch weefsel, in de context van de systemische vitamine A-toevoer om de essentiële lichtgevoelige rodopsinechromofoor 11-cis-retinal te genereren.

Kwantitatieve analyse van vitamine A-metabolieten in oculaire en niet-oculaire weefsels van muizen met behulp van hoogwaardige vloeistofchromatografie

De adsorptie van peptiden op plastic tijdens traditionele seriële verdunningen met pipetpunten kan de bepaling van de potentie aanzienlijk beïnvloeden en het begrip van structuur-activiteitsrelaties verwarren die worden gebruikt voor fasen van loodidentificatie en loodoptimalisatie in de ontdekking van geneesmiddelen. Hier worden methoden beschreven voor geautomatiseerde akoestische non-contact seriële verdunning van peptidemonsters.

Geautomatiseerde Acoustic Afgifte voor de seriële verdunning van Peptide agonisten in potentie Bepaling Testen

Dit artikel beschrijft een methode voor het beoordelen van de interacties en assemblages van integrale membraaneiwitten in vitro met verschillende partnerfactoren in een lipid-proximaal milieu.

Gebruik Steiger Liposomen lipide-proximale eiwit-eiwit interacties reconstitueren In Vitro

Dit artikel beschrijft een methode voor het bestuderen van cellulair metabolisme in complexe gemeenschappen van meerdere celtypen, met behulp van een combinatie van stabiel isotooptracering, celsortering om specifieke celtypen te isoleren en massaspectrometrie.

Een methode voor het meten Metabolisme in gesorteerde subpopulaties van Complex Cell Gemeenschappen Met behulp van stabiele isotoop Tracing

Dit protocol beschrijft de reconstructie van nucleosomen die differentieel-isotoop gemerkte zus histonen. Tegelijkertijd asymmetrisch post-translationeel gemodificeerde nucleosomen worden gegenereerd na het gebruik van een histon premodified kopie. Deze preparaten kunnen gemakkelijk worden gebruikt om wijzigingen crosstalk mechanismen bestuderen, gelijktijdig op beide zus histonen, met behulp van hoge-resolutie NMR-spectroscopie.

Reconstructie van Nucleosomen met Differentieel Isotopen-gelabelde Sister Histon

Het menselijke netvlies is samengesteld uit functioneel en moleculair verschillende regio's, met inbegrip van de fovea, macula en perifere retina. Hier beschrijven we een methode met behulp van punch biopsieën en handmatig verwijderen van de lagen weefsel van een menselijk oog te ontleden en deze verschillende retinale regio's voor downstream Proteoom analyse te verzamelen.

Dissectie van menselijke netvlies en RPE-vaatvlies voor proteoom-analyse

Wij beschreven twee chemische-gebaseerde protocollen voor het kweken van muis embryonale stamcellen in detail. Deze nieuwe methode maakt gebruik van synergetische mechanismen ter bevordering van Tet-gemedieerde oxidatie (door vitamine C) en onderdrukken van DOVO synthese van 5-methylcytosine (door PD0325901) om DNA hypomethylation en pluripotent van muis embryonale stamcellen te onderhouden.

Een alternatieve cultuur methode om Genomic Hypomethylation van muis embryonale stamcellen met MEK-remmer PD0325901 en vitamine C

Hier presenteren we een protocol van geheel-cel elektrochemische experimenten te bestuderen van de bijdrage van proton vervoer aan het tarief van extracellulaire elektronentransport via de buitenmembraan cytochromes complex in Shewanella oneidensis heer-1.

Elektrochemische detectie van Deuterium kinetisch-isotoopeffect op extracellulaire elektronentransport in Shewanella oneidensis heer-1

Stabiele koolstof en zuurstof isotoop analyse van mens en dier tandglazuur carbonaat is gebruikt als een proxy voor afzonderlijke voeding en milieu wederopbouw. Hier, wij bieden een gedetailleerde beschrijving en visuele documentatie van bulk en sequentiële tooth glazuur bemonstering alsmede voorbehandeling van archeologisch en paleontologisch monsters.

Monstername en voorbehandeling van tandglazuur carbonaat voor stabiele koolstof en zuurstof isotoop analyse

Dit protocol beschrijft een kalibratie-vrije aanpak voor het kwantificeren van eiwit homo-oligomerisatie in vitro op basis van fluctuatiemarges Fluorescentiespectroscopie met behulp van commerciële licht scanning microscopie. De juiste overname-instellingen en de analysemethoden worden weergegeven.

Kalibratie-gratis In Vitro kwantificering van eiwit Homo-oligomerisatie met behulp van commerciële instrumentatie en Software van de analyse van de helderheid van gratis, Open Source

Newcastle University.  De bereiding van stabiele, isotoopgelabelde vitamine A, noodzakelijk voor de retinolisotoopverdunningstechniek, moet voldoen aan voedselveiligheidsnormen. Het protocol toont doseringsbereiding in plantaardige olie in concentraties die geschikt zijn voor het gekozen toedieningssysteem en het toegepaste analyseplatform.

Formulering van vitamine A-tracerdoses voor toediening aan menselijke proefpersonen met behulp van de retinolisotoopverdunningstechniek

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