Chemosensory System

The chemosensory system is the biological network that detects and interprets chemical signals, enabling organisms to sense their environment and respond appropriately. Specialized receptor cells bind molecules associated with odors, tastes, or other chemical cues, initiating signal-transduction pathways that convert chemical information into electrical or cellular responses processed by the nervous system. In biology, chemosensation helps regulate feeding, predator avoidance, reproduction, navigation, and interactions between organisms and their habitats. Studying this system clarifies how cells encode environmental information and supports research on sensory disorders, neural circuitry, animal behavior, and the development of artificial chemical-sensing technologies.

Chemosensory System - Related Videos

Research

JoVE Journal - Behavior
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Automated Analysis of a Nematode Population-based Chemosensory Preference Assay

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Cited by 3 •

2017

We present a behavior recording setup and protocol that enables automated analysis of the nematode, Caenorhabditis elegans' preference for soluble compounds in a population-based assay. This article describes the construction of a behavior chamber, the behavioral assay protocol, and video analysis software usage.

Research

JoVE Journal - Behavior
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Using Enclosed Y-Mazes to Assess Chemosensory Behavior in Reptiles

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Cited by 3 •

2021

Y-mazes enable researchers to determine the relevance of specific stimuli that drive animal behavior, especially isolated chemical cues from a variety of sources. Careful design and planning can yield robust data (e.g., discrimination, degree of exploration, numerous behaviors). This experimental apparatus can provide powerful insight into behavioral and ecological questions.

Research

JoVE Journal - Neuroscience

Assaying Surface Expression of Chemosensory Receptors in Heterologous Cells

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Cited by 6 •

2011

Here we demonstrate a protocol to carry out live cell staining that can be used to detect odorant receptors on the surface of HEK293T cells conveniently. In addition, it may also be used to assay for surface expression of other chemosensory receptors or GPCRs.

Hybridization Chain Reaction RNA Whole-Mount Fluorescence In situ Hybridization of Chemosensory Genes in Mosquito Olfactory Appendages

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Cited by 1 •

2023

The article describes the methods and reagents necessary to perform hybridization chain reaction RNA whole-mount fluorescence in situ hybridization (HCR RNA WM-FISH) to reveal insights into the spatial and cellular resolution of chemosensory receptor genes in the mosquito antenna and maxillary palp.

C. elegans Chemotaxis Assay: A Method to Test Chemosensation in Worms

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2023

This video introduces chemotaxis in the nematode C. elegans and shows a sample protocol testing chemotactic aversion to copper sulfate.

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