Prophylactic Mastectomy Alternative

A prophylactic mastectomy alternative is a risk-management approach that reduces or monitors breast cancer risk without surgically removing breast tissue, particularly for people with inherited susceptibility or a strong family history. Options may include enhanced surveillance with mammography and magnetic resonance imaging, genetic counseling, and risk-reducing medications that interfere with hormone-driven tumor development. In cancer research, these strategies support individualized prevention by comparing cancer incidence, treatment outcomes, quality of life, and surgical risks across different approaches. Studying their effectiveness helps clinicians and patients weigh preventive surgery against ongoing monitoring or medical prevention based on genetic findings and personal risk.

Prophylactic Mastectomy Alternative - Related Videos

Research

JoVE EoE - Breast Cancer

Radical Mastectomy: Surgical Removal of the Entire Mammary Gland from a Mouse to Study Cancer Progression

0 Views •

2023

This video describes a technique of radical mastectomy, which is used for the surgical removal of the entire mammary gland from a mouse to study cancer progression.

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications

0 Views •

2025

This article presents a detailed protocol for collecting breast cancer samples, designed to optimize their utility for biobanking, personalized medicine, and other research applications. The workflow for sample collection, including breast biopsy and mastectomy procedures, is described in detail, focusing on minimizing tissue damage and maximizing sample quality.

Education

JoVE Core - Molecular Biology

Alternative RNA Splicing

0 Views •

2020

Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity. There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

0 Views •

Cited by 35 •

2016

Zika Virus (ZIKV), an emerging pathogen, is linked to fetal developmental abnormalities and microcephaly. The establishment of an effective infectious cell culture system is crucial for studies of ZIKV replication as well as vaccine and drug development. In this study, various virological assays pertaining to ZIKV are illustrated and discussed.

Null and Alternative Hypotheses

0 Views •

2023

The actual hypothesis testing begins by considering two hypotheses. They are termed the null hypothesis and the alternative hypothesis. These hypotheses contain opposing viewpoints. The null hypothesis, denoted by H0 is a statement of no difference between the variables—they are not related. This can often be considered the status quo. As a result if you cannot accept the null, it requires some action. The alternative hypothesis, denoted by H1 or Ha, is a claim about the population that is...

View All Results

FAQs

Related Topics