Inter-particle Contact Evolution

Inter-particle contact evolution is the study of how contacts between individual particles form, change, and disappear over time, a process that controls the behavior of many particulate systems in engineering. Under applied loading or flow, particle motion, deformation, and rearrangement alter contact number, orientation, and transmitted forces, producing changing contact networks and load paths. Tracking this evolution helps explain macroscopic properties such as stiffness, strength, compaction, and flow, with applications in granular soils, powders, packed beds, and particulate composites. It also supports improved modeling of failure, transport, and processing in engineered materials.

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Research

JoVE Journal - Biology

Molecular Evolution of the Tre Recombinase

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Cited by 4 •

2008

Here we report the generation of Tre recombinase through directed, molecular evolution. Tre recombinase recognizes a pre-defined target sequence within the LTR sequences of the HIV-1 provirus, resulting in the excision and eradication of the provirus from infected human cells. While still in its infancy, directed molecular evolution will allow the creation of custom enzymes that will serve as tools of molecular surgery and molecular medicine.

Education

JoVE Core - Molecular Biology

Synteny and Evolution

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2021

John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species. Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral chromosome underwent...

The Evidence for Evolution

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2026

Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.The collection of fossils within sedimentary rocks give a record of common ancestry and often depicts the history of evolution.

Eukaryotic Evolution

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2023

The endosymbiont theory is the most widely accepted theory of eukaryotic evolution; however, its progression is still somewhat debated. According to the nucleus-first hypothesis, the ancestral prokaryote first evolved a membrane to enclose DNA and form the nucleus. Conversely, the mitochondria-first hypothesis suggests that the nucleus was formed after endosymbiosis of mitochondria. Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...

Research

JoVE Journal - Engineering
Free Sample

Investigation of Early Plasma Evolution Induced by Ultrashort Laser Pulses

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Cited by 2 •

2012

An experimental method to examine the early plasma evolution induced by ultrashort laser pulses is described. Using this method, high quality images of early plasma are obtained with high temporal and spatial resolutions. A novel integrated atomistic model is used to simulate and explain the mechanisms of early plasma.

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