Biopsy Complications

Biopsy complications are adverse effects that can occur when tissue is removed for microscopic or molecular examination, and understanding them supports safer diagnostic care. Risk depends on the biopsy site, instrument, sampling route, and patient factors; disruption of blood vessels may cause bleeding, while tissue injury or contamination can contribute to pain, infection, hematoma, or damage to nearby structures. Most complications are minor, but clinicians assess warning signs such as persistent bleeding, fever, worsening pain, or impaired function. Knowledge of these outcomes guides informed consent, procedural planning, monitoring, and timely management while preserving the diagnostic value of biopsy in medicine.

Biopsy Complications - Related Videos

Research

JoVE Journal - Medicine

A Technique for Subcutaneous Abdominal Adipose Tissue Biopsy via a Non-diathermy Method

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Cited by 7 •

2017

We standardized an abdominal adipose tissue biopsy using a non-diathermy method performed under local anesthesia. Three cases of excessive post-operation bleeding out of 115 operations (2.61%) occurred.We conclude that an abdominal adipose tissue surgical biopsy using a non-diathermy method can be safely applied to healthy men.

Education

JoVE Core - Pathophysiology

Healing II: Complications

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2026

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

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Cited by 5 •

2015

Here, we present a protocol for use at the time of transrectal ultrasound guided prostate needle biopsy (TRUS PNB) that is a simple and cost-effective means to reduce infections following the procedure.

Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome

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Cited by 18 •

2016

This video demonstrates the technique of percutaneous muscle biopsy of the human vastus lateralis using the Weil-Blakesley conchotome.

Three-dimensional Imaging of Nociceptive Intraepidermal Nerve Fibers in Human Skin Biopsies

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Cited by 5 •

2013

In order to study the changes of nociceptive intraepidermal nerve fibers (IENFs) in painful neuropathies (PN), we developed protocols that could directly examine three-dimensional morphological changes observed in nociceptive IENFs. Three-dimensional analysis of IENFs has the potential to evaluate the morphological changes of IENF in PN.

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