Flow Probes

Flow probes are medical sensing devices that measure the movement or volume of fluids, especially blood, through vessels or clinical equipment. Depending on the design, they use ultrasound to detect Doppler frequency shifts caused by moving blood cells or compare the transit time of acoustic signals traveling with and against the flow, producing quantitative flow measurements. Clinicians and researchers use these measurements to assess tissue perfusion, monitor cardiovascular function, evaluate vascular grafts, and guide surgical procedures. By providing real-time hemodynamic data, flow probes support diagnosis, treatment decisions, and experimental studies of circulation.

Flow Probes - Related Videos

Research

JoVE EoE - Rodent Models

Positioning Laser Doppler Probe: A Technique to Implant Probe Over Middle Cerebral Artery for Blood Flow Measurement in Murine Model

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2025

This video describes the surgical procedure to immobilize the laser Doppler probe over the murine brain's middle cerebral artery, or MCA. The probe helps to measure the blood flow in the brain's microvasculature by measuring the Doppler shift caused due to the motion of red blood cells within the artery.

Molecular Probe Optimization to Determine Cell Mortality in a Photosynthetic Organism (Microcystis aeruginosa) Using Flow Cytometry

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Cited by 2 •

2016

Microbial populations contain substantial cell heterogeneity, which can dictate overall behavior. Molecular probe analysis through flow cytometry can determine physiological states of cells, however its application varies between species. This study provides a protocol to accurately determine cell mortality within a cyanobacterium population, without underestimating or recording false positive results.

Laser Doppler Needle Probe Insertion: A Technique for Real-time Quantification of Blood Flow within the Spinal Cord in a Porcine Model

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2025

This video demonstrates the placement of a laser Doppler needle probe in the spinal cord of a porcine model. This helps in the continuous quantification of blood supply to the spinal cord, an important assessment in spinal cord injury.

Flow Cytometry Assay to Quantify Oxidative Stress: An Assay to Quantify Reactive Oxygen Species in Intestinal Organoids Using Fluorogenic Probes

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2025

This video demonstrates a flow cytometry assay to quantify the ROS levels in 3D intestinal organoids obtained from GFP-expressing transgenic mice. This method provides an in vitro experimental model to investigate the efficacy of test compounds on ROS production.

Measurement of Bioelectric Current with a Vibrating Probe

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Cited by 15 •

2011

The manufacture, calibration and use of non-invasive vibrating probes to measure bioelectric current in various biological systems is described.

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