Image Guided Radiotherapy
Image Guided Radiotherapy - Related Videos
11:38
Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
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Cited by 49 •
2014
The current priority in breast cancer radiotherapy is to reduce cardiac doses without compromising target tissue coverage. The voluntary breath-hold technique described here is a simple, inexpensive solution to this problem and capable of being instituted widely without the need for specialized equipment.
11:24
Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
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Cited by 10 •
2011
Brain tumor patients routinely undergo cranial radiotherapy, and while beneficial, this treatment often results in debilitating cognitive dysfunction. This serious unresolved problem has at present, no clinical recourse, and has driven our efforts to devise stem cell based therapies for the recovery of radiation-induced cognitive decrements.
08:02
Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model
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Cited by 9 •
2012
The purpose of this article is to describe the use of an orthotopic glioblastoma model for chemoradiation studies. This article will go though cell processing, implanting, and radiotherapy of the mouse using an intracranial model.
10:10
Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
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Cited by 6 •
2011
Cognitive impairment resulting from the radiotherapeutic management of brain tumors represents a clinically intractable condition that adversely impacts quality of life. The capability to critically evaluate potential interventions for ameliorating radiation-induced cognitive decrements ultimately depends on the capability to undertake rigorous quantitative assessments of cognition.
10:53
Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks
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Cited by 10 •
2017
This protocol outlines the implementation of image-guided, laser-based hydrogel degradation to fabricate vascular-derived, biomimetic microfluidic networks embedded in poly(ethylene glycol) diacrylate (PEGDA) hydrogels. These biomimetic microfluidic systems may be useful for tissue engineering applications, generation of in vitro disease models, and fabrication of advanced "on-a-chip" devices.
FAQs
By comparing imaging obtained before or during a treatment session with the expected treatment setup, clinicians can detect shifts in patient position or changes in tumor location. They can then correct alignment or adapt the radiation fields before or during delivery. This process is particularly useful when anatomy changes between sessions or when the target lies close to sensitive healthy tissue.
Computed tomography, X-ray, and ultrasound provide different ways to verify the relationship between the tumor, the patient’s anatomy, and the planned treatment position. The overview identifies these modalities as tools used before or during therapy, rather than as interchangeable steps in every case. Their common purpose is to supply current localization information for more individualized radiation delivery.
Motion from breathing can alter the tumor’s location while radiation is being delivered, creating a risk that the intended target and radiation field will no longer align. Image guidance helps clinicians recognize this motion-related uncertainty and respond through positioning or field adjustments. This makes the approach especially relevant to tumors in sites affected by respiration or other anatomical movement.
Precision matters most when a tumor is near an organ or other healthy structure that should receive as little radiation as possible. Imaging can confirm whether the planned geometry remains appropriate for the patient’s current anatomy, supporting targeted delivery while limiting unnecessary exposure nearby. Thus, the value of image guidance depends not only on tumor location but also on surrounding anatomy.
At a basic level, clinicians obtain medical images before or during treatment, review tumor location and patient positioning, and determine whether the current setup matches the intended plan. If discrepancies appear, they can shift the patient or modify radiation fields. The sequence links imaging, clinical review, and delivery rather than treating imaging as a separate diagnostic step.
Image-guided radiotherapy is especially useful when the target is close to sensitive organs, because small setup or anatomical differences may affect how radiation reaches nearby tissue. It is also valuable for tumors influenced by breathing or other motion. In these situations, current localization can support treatment decisions tailored to the patient’s anatomy at the time of therapy.
It provides treatment-relevant information about patient positioning, tumor location, and changes in anatomy or motion. That information can guide a positional shift or a modification of the radiation field, helping clinicians judge whether the intended delivery remains appropriate. In medicine, the resulting benefit is more individualized cancer care with emphasis on accuracy and protection of nearby healthy tissue.