Honeybee Gene Regulation

Honeybee gene regulation is the control of when and where genes are activated in honeybee cells, shaping neural development, behavior, and responses to the colony environment. Transcription factors, DNA methylation, and other epigenetic mechanisms influence gene expression without changing the underlying DNA sequence, allowing nutrition, social interactions, and experience to affect neuronal function. In neuroscience, studying these regulatory processes helps explain how honeybees develop distinct behaviors such as learning, memory, communication, and division of labor. This system provides a valuable model for linking molecular changes in the brain with behavior and for examining how environmental conditions influence neural plasticity.

Honeybee Gene Regulation - Related Videos

Education

JoVE Core - Microbiology

Gene Regulation During Sporulation

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2025

Sporulation is a complex developmental process that allows certain Gram-positive bacteria, such as Bacillus subtilis and Clostridium species, to survive extreme environmental conditions. This process is tightly regulated by a series of signaling cascades and transcriptional controls, ensuring the formation of a highly resistant endospore.Sporulation is triggered by unfavorable conditions, such as nutrient depletion, and is governed by a phosphorelay system. One of the sensor kinases, such as...

Research

JoVE Journal - Neuroscience
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Simultaneous Long-term Recordings at Two Neuronal Processing Stages in Behaving Honeybees

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Cited by 16 •

2014

Simultaneous extracellular long term recordings from two different brain neuropiles or two different anatomical tracts were established in honeybees. These recordings allow the investigation of temporal aspects of neuronal processing across different brain areas at the single neuron as well as at the ensemble level in a behaving animal.

Reporter Gene Repression Assay to Study Translational Regulation of a Target Gene

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2025

This video demonstrates an in vivo assay in bacteria to study the interaction of RNA-binding proteins (RBPs) with RNA. The bacterial cells are transformed with two plasmid constructs — a binding-site plasmid encoding an mRNA containing a fluorescent reporter gene downstream of an RBP-binding site — while an RBP plasmid expresses the RBP proteins under the control of an inducer. Upon inducer-mediated increase in RBP production, the RBPs bind to the mRNA, resulting in translational repression of...

Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System

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Cited by 5 •

2016

Here we describe our detailed protocol for the preparation of single-cohort honeybee colonies – a useful tool for analyzing the role-associated worker physiology. We also describe detailed protocols for treating workers with juvenile hormone and ecdysone to evaluate the involvement of these hormones in the regulation of worker behavior and/or physiology.

Circadian Rhythms and Gene Regulation

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2021

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...

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