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September 26, 2011
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In order to evaluate novel therapeutic paradigms for the treatment of glioma, physiological relevant models are essential. We utilize an implantable guide screw procedure for establishment of intracranial xenograft models that is more rapid and safer than stereotactic approaches.
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Donoghue, J. F., Bogler, O., Johns, T. G. A Simple Guide Screw Method for Intracranial Xenograft Studies in Mice. J. Vis. Exp. (55), e3157, doi:10.3791/3157 (2011).
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