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09:11 min
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September 17, 2014
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In this paper, we demonstrate a standard method for producing an embolic middle cerebral artery occlusion with homologous blood clots (fibrin-rich) in adult rat. This model closely mimics human ischemic stroke and is suitable for preclinical study of thrombolytic therapy for ischemic stroke.
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Jin, R., Zhu, X., Li, G. Embolic Middle Cerebral Artery Occlusion (MCAO) for Ischemic Stroke with Homologous Blood Clots in Rats. J. Vis. Exp. (91), e51956, doi:10.3791/51956 (2014).
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