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September 09, 2016
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This manuscript presents an injection molding method to engineer microvessels that recapitulate physiological properties of endothelium. The microfluidic-based process creates patent 3D vascular networks with tailorable conditions, such as flow, cellular composition, geometry, and biochemical gradients. The fabrication process and examples of potential applications are described.
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Roberts, M. A., Kotha, S. S., Phong, K. T., Zheng, Y. Micropatterning and Assembly of 3D Microvessels. J. Vis. Exp. (115), e54457, doi:10.3791/54457 (2016).
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