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Probing The Structure And Dynamics Of Nucleosomes Using Atomic Force Microscopy Imaging
Probing The Structure And Dynamics Of Nucleosomes Using Atomic Force Microscopy Imaging
JoVE Journal
Biochemia
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JoVE Journal Biochemia
Probing The Structure And Dynamics Of Nucleosomes Using Atomic Force Microscopy Imaging

Probing The Structure And Dynamics Of Nucleosomes Using Atomic Force Microscopy Imaging

English

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09:52 min

January 31, 2019

DOI:

09:52 min
January 31, 2019

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Here, we present a protocol to characterize nucleosome particles at the single-molecule level using static and time-lapse atomic force microscopy (AFM) imaging techniques. The surface functionalization method described allows for the capture of the structure and dynamics of nucleosomes in high-resolution at the nanoscale.

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