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November 02, 2019
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This animal model enables researchers to induce statistically significant secondary lymphedema in the hindlimb of mice, lasting at least 8 weeks. The model can be used to study the pathophysiology of lymphedema and to investigate novel treatment options.
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Wiinholt, A., Jørgensen, M. G., Bučan, A., Dalaei, F., Sørensen, J. A. A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice. J. Vis. Exp. (153), e60578, doi:10.3791/60578 (2019).
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