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August 15, 2020
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Here, we introduce and describe widely accessible methodologies utilizing some versatile nematode models, including hyperactivated ion channel-induced necrosis and protein aggregate-induced neurotoxicity, to monitor and dissect the cellular and molecular underpinnings of age-associated neurodegenerative diseases.
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Palikaras, K., Tavernarakis, N. Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans. J. Vis. Exp. (162), e61169, doi:10.3791/61169 (2020).
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