Intramyocardial Transplantation of MSC-Loading Injectable Hydrogels after Myocardial Infarction in a Murine Model

Chan Woo Kim; Chan Joon Kim; Eun-Hye Park; Eunmi Lee; Eunhwa Seong; Kiyuk Chang

doi:10.3791/61752

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Intramyocardial Transplantation of MSC-Loading Injectable Hydrogels after Myocardial Infarction in a Murine Model

JoVE Journal
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JoVE Journal Medycyna

Intramyocardial Transplantation of MSC-Loading Injectable Hydrogels after Myocardial Infarction in a Murine Model

4,348 Views

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09:19 min

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September 20, 2020

DOI:

10.3791/61752-v

DOI:

10.3791/61752-v

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09:19 min

September 20, 2020

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3 Views

Chan Woo Kim^1,2, Chan Joon Kim^1,3, Eun-Hye Park^1,2, Eunmi Lee^1,2, Eunhwa Seong^1,2, Kiyuk Chang^1,2

¹Cardiovascular Research Institute for Intractable Disease, College of Medicine,The Catholic University of Korea, ²Division of Cardiology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine,The Catholic University of Korea, ³Division of Cardiology, Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine,The Catholic University of Korea

Transkrypcja

Podsumowanie

Stem cell-based therapy has emerged as an efficient strategy to repair injured cardiac tissues after myocardial infarction. We provide an optimal in vivo application for stem cell transplantation using gelatin hydrogels that are able to be enzymatically cross-linked.