Brian D. Robertson MRC Centre for Molecular Bacteriology and Infection, Department of Medicine Imperial College London Biography Publications Institution JoVE Articles Brian D. Robertson has not added a biography. If you are Brian D. Robertson and would like to personalize this page please email our Author Liaison for assistance. Publications An Auto-luminescent Fluorescent BCG Whole Blood Assay to Enable Evaluation of Paediatric Mycobacterial Responses Using Minimal Blood Volumes Frontiers in Pediatrics. 2019 | Pubmed ID: 31114771 Effective Delivery of the Anti-mycobacterial Peptide NZX in Mesoporous Silica Nanoparticles PloS One. 2019 | Pubmed ID: 30807612 Characterization of Two New Multidrug-Resistant Strains of : Tools for Routine In Vitro Screening of Novel Anti-Mycobacterial Agents Antibiotics (Basel, Switzerland). Jan, 2019 | Pubmed ID: 30609766 Inhalable Poly(lactic-co-glycolic Acid) (PLGA) Microparticles Encapsulating All-trans-Retinoic Acid (ATRA) As a Host-directed, Adjunctive Treatment for Mycobacterium Tuberculosis Infection European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Jan, 2019 | Pubmed ID: 30385419 A Novel Derivative of the Fungal Antimicrobial Peptide Plectasin is Active Against Mycobacterium Tuberculosis Tuberculosis (Edinburgh, Scotland). 12, 2018 | Pubmed ID: 30514507 Galleria Mellonella - a Novel Infection Model for the Mycobacterium Tuberculosis Complex Virulence. 2018 | Pubmed ID: 30067135 Rifampin- or Capreomycin-Induced Remodeling of the Mycolic Acid Layer Is Mitigated in Synergistic Combinations with Cationic Antimicrobial Peptides MSphere. 07, 2018 | Pubmed ID: 30021876 Analysis of ParAB Dynamics in Mycobacteria Shows Active Movement of ParB and Differential Inheritance of ParA PloS One. 2018 | Pubmed ID: 29920558 Characterising Resuscitation Promoting Factor Fluorescent-fusions in Mycobacteria BMC Microbiology. 04, 2018 | Pubmed ID: 29649975 Platelets Regulate Pulmonary Inflammation and Tissue Destruction in Tuberculosis American Journal of Respiratory and Critical Care Medicine. Jul, 2018 | Pubmed ID: 29420060 Mycobacteria Modify Their Cell Size Control Under Sub-Optimal Carbon Sources Frontiers in Cell and Developmental Biology. 2017 | Pubmed ID: 28748182 Disruption of Drug-resistant Biofilms Using De Novo Designed Short α-helical Antimicrobial Peptides with Idealized Facial Amphiphilicity Acta Biomaterialia. 07, 2017 | Pubmed ID: 28457962 Unnatural Amino Acid Analogues of Membrane-active Helical Peptides with Anti-mycobacterial Activity and Improved Stability The Journal of Antimicrobial Chemotherapy. 08, 2016 | Pubmed ID: 27118774 Population Genomics of Mycobacterium Tuberculosis in Ethiopia Contradicts the Virgin Soil Hypothesis for Human Tuberculosis in Sub-Saharan Africa Current Biology : CB. Dec, 2015 | Pubmed ID: 26687624 Deciphering the Metabolic Response of Mycobacterium Tuberculosis to Nitrogen Stress Molecular Microbiology. Sep, 2015 | Pubmed ID: 26077160 Mycobacterial Growth Cold Spring Harbor Perspectives in Medicine. May, 2015 | Pubmed ID: 25957314 Investigation of the High Rates of Extrapulmonary Tuberculosis in Ethiopia Reveals No Single Driving Factor and Minimal Evidence for Zoonotic Transmission of Mycobacterium Bovis Infection BMC Infectious Diseases. Mar, 2015 | Pubmed ID: 25886866 The Extracellular Matrix Regulates Granuloma Necrosis in Tuberculosis The Journal of Infectious Diseases. Aug, 2015 | Pubmed ID: 25676469 Cell Electrospinning: an in Vitro and in Vivo Study Small (Weinheim an Der Bergstrasse, Germany). Jan, 2014 | Pubmed ID: 23894081 Pathways of IL-1β Secretion by Macrophages Infected with Clinical Mycobacterium Tuberculosis Strains Tuberculosis (Edinburgh, Scotland). Sep, 2013 | Pubmed ID: 23849220 Deciphering the Response of Mycobacterium Smegmatis to Nitrogen Stress Using Bipartite Active Modules BMC Genomics. Jul, 2013 | Pubmed ID: 23819599 Genome Wide Analysis of the Complete GlnR Nitrogen-response Regulon in Mycobacterium Smegmatis BMC Genomics. May, 2013 | Pubmed ID: 23642041 Rapid in Vivo Assessment of Drug Efficacy Against Mycobacterium Tuberculosis Using an Improved Firefly Luciferase The Journal of Antimicrobial Chemotherapy. Sep, 2013 | Pubmed ID: 23633686 Adenylylation of Mycobacterial Glnk (PII) Protein is Induced By nitrogen Limitation Tuberculosis (Edinburgh, Scotland). Mar, 2013 | Pubmed ID: 23352854 Database Resources for the Tuberculosis Community Tuberculosis (Edinburgh, Scotland). Jan, 2013 | Pubmed ID: 23332401 Bioinformatic and Empirical Analysis of Novel Hypoxia-inducible Targets of the Human Antituberculosis T Cell Response Journal of Immunology (Baltimore, Md. : 1950). Dec, 2012 | Pubmed ID: 23169589 The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium Tuberculosis Infected Macrophages is Not Dependent on Bacterial Virulence PloS One. 2012 | Pubmed ID: 23118880 Detection and Treatment of Subclinical Tuberculosis Tuberculosis (Edinburgh, Scotland). Nov, 2012 | Pubmed ID: 22819716 In Vitro and in Vivo Interrogation of Bio-sprayed Cells Small (Weinheim an Der Bergstrasse, Germany). Aug, 2012 | Pubmed ID: 22648794 A New in Vivo Model to Test Anti-tuberculosis Drugs Using Fluorescence Imaging The Journal of Antimicrobial Chemotherapy. Aug, 2012 | Pubmed ID: 22635525 Aspartate D48 is Essential for the GlnR-mediated Transcriptional Response to Nitrogen Limitation in Mycobacterium Smegmatis FEMS Microbiology Letters. May, 2012 | Pubmed ID: 22356601 La Influencia De La Raza De Ganado En La Susceptibilidad a La Tuberculosis Bovina En Etiopía Comparative Immunology, Microbiology and Infectious Diseases. Feb, 2012 | Pubmed ID: 22304898 Rapid Measurement of Antituberculosis Drug Activity in Vitro and in Macrophages Using Bioluminescence The Journal of Antimicrobial Chemotherapy. Feb, 2012 | Pubmed ID: 22101217 Mycobacterium Tuberculosis Lineage Influences Innate Immune Response and Virulence and is Associated with Distinct Cell Envelope Lipid Profiles PloS One. 2011 | Pubmed ID: 21931620 The Mycobacterium Tuberculosis β-oxidation Genes EchA5 and FadB3 Are Dispensable for Growth in Vitro and in Vivo Tuberculosis (Edinburgh, Scotland). Nov, 2011 | Pubmed ID: 21764638 MMP-1 Drives Immunopathology in Human Tuberculosis and Transgenic Mice The Journal of Clinical Investigation. May, 2011 | Pubmed ID: 21519144 Targeting the Chromosome Partitioning Protein ParA in Tuberculosis Drug Discovery The Journal of Antimicrobial Chemotherapy. Nov, 2010 | Pubmed ID: 20810423 Optimización De Los Reporteros Bioluminiscentes Para Su Uso Con Micobacterias PloS One. 2010 | Pubmed ID: 20520722 Improved Mycobacterial Tetracycline Inducible Vectors Plasmid. Sep, 2010 | Pubmed ID: 20434484 Detección Sensible De La Expresión Génica En Micobacterias Bajo Condiciones Replicar Y No Replicante-Uso Optimizado Rojo Lejano Reporteros PloS One. 2010 | Pubmed ID: 20352111 Bioluminescent Monitoring of in Vivo Colonization and Clearance Dynamics by Light-emitting Bacteria Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19685306 Unusual Features of the Cell Cycle in Mycobacteria: Polar-restricted Growth and the Snapping-model of Cell Division Tuberculosis (Edinburgh, Scotland). May, 2007 | Pubmed ID: 17287144 Mycobacterial Mutants with Defective Control of Phagosomal Acidification PLoS Pathogens. Nov, 2005 | Pubmed ID: 16322769 Alternative Luciferase for Monitoring Bacterial Cells Under Adverse Conditions Applied and Environmental Microbiology. Jul, 2005 | Pubmed ID: 16000745 The OtsAB Pathway is Essential for Trehalose Biosynthesis in Mycobacterium Tuberculosis The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15703182 Tetracycline-inducible Gene Regulation in Mycobacteria Nucleic Acids Research. Feb, 2005 | Pubmed ID: 15687380 El Acompañante Sensible Al Estrés Alfa-cristalina 2 Se Requiere Para La Patogenesia De Mycobacterium Tuberculosis Molecular Microbiology. Feb, 2005 | Pubmed ID: 15686559 Visualization of Microarray Results to Assist Interpretation Tuberculosis (Edinburgh, Scotland). 2004 | Pubmed ID: 15207497 Analysis of the Function of Mycobacterial DnaJ Proteins by Overexpression and Microarray Profiling Tuberculosis (Edinburgh, Scotland). 2004 | Pubmed ID: 15207487 Tuberculosis: a Problem with Persistence Nature Reviews. Microbiology. Nov, 2003 | Pubmed ID: 15035039 Uso de la Invertebrada Galleria mellonella como Modelo de Infección para Estudiar el Complejo Mycobacterium tuberculosis Masanori Asai*1, Yanwen Li*1, Jasmeet Singh Khara1,2, Camilla A. Gladstone1, Brian D. Robertson3, Paul R. Langford*1, Sandra M. Newton*1 1Section of Pediatric Infectious Diseases and Allergy, Department of Medicine, Imperial College London, 2Department of Pharmacy, National University of Singapore, 3MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London JoVE 59703 Imunologia e Infecção
Uso de la Invertebrada Galleria mellonella como Modelo de Infección para Estudiar el Complejo Mycobacterium tuberculosis Masanori Asai*1, Yanwen Li*1, Jasmeet Singh Khara1,2, Camilla A. Gladstone1, Brian D. Robertson3, Paul R. Langford*1, Sandra M. Newton*1 1Section of Pediatric Infectious Diseases and Allergy, Department of Medicine, Imperial College London, 2Department of Pharmacy, National University of Singapore, 3MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London JoVE 59703 Imunologia e Infecção