Jean-Pierre Gorvel

Publications

• Functional Specialty of CD40 and Dendritic Cell Surface Lectins for Exogenous Antigen Presentation to CD8(+) and CD4(+) T Cells
  EBioMedicine. Mar, 2016  |   Pubmed ID: 27077111
• Effector Proteins Support the Asymmetric Apportioning of Salmonella During Cytokinesis
  Virulence. Aug, 2016  |   Pubmed ID: 27046257
• Structural Studies of Lipopolysaccharide-defective Mutants from Brucella Melitensis Identify a Core Oligosaccharide Critical in Virulence
  The Journal of Biological Chemistry. Apr, 2016  |   Pubmed ID: 26867577
• Brucella Discriminates Between Mouse Dendritic Cell Subsets Upon in Vitro Infection
  Virulence. 2016  |   Pubmed ID: 26606688
• Gene Expression Profiling of the Peyer's Patch Mononuclear Phagocyte System
  Genomics Data. Sep, 2015  |   Pubmed ID: 26484215
• Subversion of Mouse Dendritic Cell Subset Function by Bacterial Pathogens
  Microbial Pathogenesis. Dec, 2015  |   Pubmed ID: 26453826
• RUN and FYVE Domain-containing Protein 4 Enhances Autophagy and Lysosome Tethering in Response to Interleukin-4
  The Journal of Cell Biology. Sep, 2015  |   Pubmed ID: 26416964
• The Salmonella Effector Protein SifA Plays a Dual Role in Virulence
  Scientific Reports. 2015  |   Pubmed ID: 26268777
• Brucella Abortus Induces the Premature Death of Human Neutrophils Through the Action of Its Lipopolysaccharide
  PLoS Pathogens. May, 2015  |   Pubmed ID: 25946018
• Innate and Adaptive Immune Functions of Peyer's Patch Monocyte-derived Cells
  Cell Reports. May, 2015  |   Pubmed ID: 25921539
• Escherichia Coli α-hemolysin Counteracts the Anti-virulence Innate Immune Response Triggered by the Rho GTPase Activating Toxin CNF1 During Bacteremia
  PLoS Pathogens. Mar, 2015  |   Pubmed ID: 25781937
• Brucella CβG Induces a Dual Pro- and Anti-inflammatory Response Leading to a Transient Neutrophil Recruitment
  Virulence. 2015  |   Pubmed ID: 25654761
• Cervical Lymph Nodes As a Selective Niche for Brucella During Oral Infections
  PloS One. 2014  |   Pubmed ID: 25919005
• Myeloid Decidual Dendritic Cells and Immunoregulation of Pregnancy: Defective Responsiveness to Coxiella Burnetii and Brucella Abortus
  Frontiers in Cellular and Infection Microbiology. 2014  |   Pubmed ID: 25566514
• Intracellular Bacteria Interfere with Dendritic Cell Functions: Role of the Type I Interferon Pathway
  PloS One. 2014  |   Pubmed ID: 24915541
• "If You Bring an Alarm, We Will Destroy It," Said Brucella to the Host Cell
  Virulence. May, 2014  |   Pubmed ID: 24786767
• Human Plasma Cells Express Granzyme B
  European Journal of Immunology. Jan, 2014  |   Pubmed ID: 24114594
• A Toxin-antitoxin Module of Salmonella Promotes Virulence in Mice
  PLoS Pathogens. 2013  |   Pubmed ID: 24385907
• In Vivo Identification and Characterization of CD4⁺ Cytotoxic T Cells Induced by Virulent Brucella Abortus Infection
  PloS One. 2013  |   Pubmed ID: 24367519
• Bartonella and Brucella--weapons and Strategies for Stealth Attack
  Cold Spring Harbor Perspectives in Medicine. Aug, 2013  |   Pubmed ID: 23906880
• BtpB, a Novel Brucella TIR-containing Effector Protein with Immune Modulatory Functions
  Frontiers in Cellular and Infection Microbiology. 2013  |   Pubmed ID: 23847770
• Neutrophils Exert a Suppressive Effect on Th1 Responses to Intracellular Pathogen Brucella Abortus
  PLoS Pathogens. Feb, 2013  |   Pubmed ID: 23458832
• Lipopolysaccharides with Acylation Defects Potentiate TLR4 Signaling and Shape T Cell Responses
  PloS One. 2013  |   Pubmed ID: 23390517
• Brucella Evasion of Adaptive Immunity
  Future Microbiology. Feb, 2013  |   Pubmed ID: 23374122
• Brucella T4SS: the VIP Pass Inside Host Cells
  Current Opinion in Microbiology. Feb, 2013  |   Pubmed ID: 23318140
• Pathogenic Brucellae Replicate in Human Trophoblasts
  The Journal of Infectious Diseases. Apr, 2013  |   Pubmed ID: 23303808
• Lipopolysaccharide As a Target for Brucellosis Vaccine Design
  Microbial Pathogenesis. May, 2013  |   Pubmed ID: 23219811
• Small GTPases and Brucella Entry into the Endoplasmic Reticulum
  Biochemical Society Transactions. Dec, 2012  |   Pubmed ID: 23176479
• Brucella β 1,2 Cyclic Glucan is an Activator of Human and Mouse Dendritic Cells
  PLoS Pathogens. 2012  |   Pubmed ID: 23166489
• The Lipopolysaccharide Core of Brucella Abortus Acts As a Shield Against Innate Immunity Recognition
  PLoS Pathogens. 2012  |   Pubmed ID: 22589715
• The Differential Production of Cytokines by Human Langerhans Cells and Dermal CD14(+) DCs Controls CTL Priming
  Blood. Jun, 2012  |   Pubmed ID: 22535664
• What Have We Learned from Brucellosis in the Mouse Model?
  Veterinary Research. 2012  |   Pubmed ID: 22500859
• Internal Affairs: Investigating the Brucella Intracellular Lifestyle
  FEMS Microbiology Reviews. May, 2012  |   Pubmed ID: 22373010
• Peyer's Patch Dendritic Cells Sample Antigens by Extending Dendrites Through M Cell-specific Transcellular Pores
  Gastroenterology. Mar, 2012  |   Pubmed ID: 22155637
• In Search of Brucella Abortus Type IV Secretion Substrates: Screening and Identification of Four Proteins Translocated into Host Cells Through VirB System
  Cellular Microbiology. Aug, 2011  |   Pubmed ID: 21707904
• Identification of a Brucella Spp. Secreted Effector Specifically Interacting with Human Small GTPase Rab2
  Cellular Microbiology. Jul, 2011  |   Pubmed ID: 21501366
• Salmonella Detoxifying Enzymes Are Sufficient to Cope with the Host Oxidative Burst
  Molecular Microbiology. May, 2011  |   Pubmed ID: 21362067
• An Evolutionary Strategy for a Stealthy Intracellular Brucella Pathogen
  Immunological Reviews. Mar, 2011  |   Pubmed ID: 21349096
• Brucella Abortus Ornithine Lipids Are Dispensable Outer Membrane Components Devoid of a Marked Pathogen-associated Molecular Pattern
  PloS One. 2011  |   Pubmed ID: 21249206
• Contrasting Roles of Macrophages and Dendritic Cells in Controlling Initial Pulmonary Brucella Infection
  European Journal of Immunology. Dec, 2010  |   Pubmed ID: 21108467
• The Virulence Protein SopD2 Regulates Membrane Dynamics of Salmonella-containing Vacuoles
  PLoS Pathogens. 2010  |   Pubmed ID: 20664790
• Inactivation of Formyltransferase (wbkC) Gene Generates a Brucella Abortus Rough Strain That is Attenuated in Macrophages and in Mice
  Vaccine. Aug, 2010  |   Pubmed ID: 20580469
• Helicobacter Pylori Impairs Murine Dendritic Cell Responses to Infection
  PloS One. 2010  |   Pubmed ID: 20523725
• Transcriptome Analysis of the Brucella Abortus BvrR/BvrS Two-component Regulatory System
  PloS One. 2010  |   Pubmed ID: 20422049
• SKIP, the Host Target of the Salmonella Virulence Factor SifA, Promotes Kinesin-1-dependent Vacuolar Membrane Exchanges
  Traffic (Copenhagen, Denmark). Jul, 2010  |   Pubmed ID: 20406420
• The Brucella Abortus Phosphoglycerate Kinase Mutant is Highly Attenuated and Induces Protection Superior to That of Vaccine Strain 19 in Immunocompromised and Immunocompetent Mice
  Infection and Immunity. May, 2010  |   Pubmed ID: 20194591
• Bacterial Manipulation of Innate Immunity to Promote Infection
  Nature Reviews. Microbiology. Feb, 2010  |   Pubmed ID: 20075926
• Pathogenic Bacteria and Dead Cells Are Internalized by a Unique Subset of Peyer's Patch Dendritic Cells That Express Lysozyme
  Gastroenterology. Jan, 2010  |   Pubmed ID: 19800337
• Interaction Between the SifA Virulence Factor and Its Host Target SKIP is Essential for Salmonella Pathogenesis
  The Journal of Biological Chemistry. Nov, 2009  |   Pubmed ID: 19801640
• Brucella Abortus Induces Irgm3 and Irga6 Expression Via Type-I IFN by a MyD88-dependent Pathway, Without the Requirement of TLR2, TLR4, TLR5 and TLR9
  Microbial Pathogenesis. Dec, 2009  |   Pubmed ID: 19747534
• The Glyceraldehyde-3-phosphate Dehydrogenase and the Small GTPase Rab 2 Are Crucial for Brucella Replication
  PLoS Pathogens. Jun, 2009  |   Pubmed ID: 19557163
• The Differential Interaction of Brucella and Ochrobactrum with Innate Immunity Reveals Traits Related to the Evolution of Stealthy Pathogens
  PloS One. 2009  |   Pubmed ID: 19529776
• Is Brucella an Enteric Pathogen?
  Nature Reviews. Microbiology. Mar, 2009  |   Pubmed ID: 19172149
• Brucella: a Mr "Hide" Converted into Dr Jekyll
  Microbes and Infection / Institut Pasteur. Jul, 2008  |   Pubmed ID: 18664389
• Brucellosis Vaccines: Assessment of Brucella Melitensis Lipopolysaccharide Rough Mutants Defective in Core and O-polysaccharide Synthesis and Export
  PloS One. 2008  |   Pubmed ID: 18648644
• Nanobacteria Are Mineralo Fetuin Complexes
  PLoS Pathogens. Feb, 2008  |   Pubmed ID: 18282102
• Brucella Control of Dendritic Cell Maturation is Dependent on the TIR-containing Protein Btp1
  PLoS Pathogens. Feb, 2008  |   Pubmed ID: 18266466
• Analysis of Kinesin Accumulation on Salmonella-containing Vacuoles
  Methods in Molecular Biology (Clifton, N.J.). 2007  |   Pubmed ID: 18363240
• Virulence Factors in Brucellosis: Implications for Aetiopathogenesis and Treatment
  Expert Reviews in Molecular Medicine. 2007  |   Pubmed ID: 18088444
• Proteome Analysis of Rickettsia Felis Highlights the Expression Profile of Intracellular Bacteria
  Proteomics. Apr, 2007  |   Pubmed ID: 17385819
• Microbiology. Bacterial Bushwacking Through a Microtubule Jungle
  Science (New York, N.Y.). Nov, 2006  |   Pubmed ID: 17095683
• The Translocated Salmonella Effector Proteins SseF and SseG Interact and Are Required to Establish an Intracellular Replication Niche
  Infection and Immunity. Dec, 2006  |   Pubmed ID: 17015457
• Mimivirus Giant Particles Incorporate a Large Fraction of Anonymous and Unique Gene Products
  Journal of Virology. Dec, 2006  |   Pubmed ID: 16971431
• The Salmonella Effector Protein PipB2 is a Linker for Kinesin-1
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006  |   Pubmed ID: 16938850
• Synthesis of Phosphatidylcholine, a Typical Eukaryotic Phospholipid, is Necessary for Full Virulence of the Intracellular Bacterial Parasite Brucella Abortus
  Cellular Microbiology. Aug, 2006  |   Pubmed ID: 16882035
• Identification of Two Putative Rickettsial Adhesins by Proteomic Analysis
  Research in Microbiology. Sep, 2006  |   Pubmed ID: 16574381
• Pathogen-endoplasmic-reticulum Interactions: in Through the out Door
  Nature Reviews. Immunology. Feb, 2006  |   Pubmed ID: 16491138
• Differential Inductions of TNF-alpha and IGTP, IIGP by Structurally Diverse Classic and Non-classic Lipopolysaccharides
  Cellular Microbiology. Mar, 2006  |   Pubmed ID: 16469053
• Characterization of Brucella Abortus Lipopolysaccharide Macrodomains As Mega Rafts
  Cellular Microbiology. Feb, 2006  |   Pubmed ID: 16441431
• Molecular Motors Hijacking by Intracellular Pathogens
  Cellular Microbiology. Jan, 2006  |   Pubmed ID: 16367863
• Rickettsia Conorii and R. Prowazekii Proteome Analysis by 2DE-MS: a Step Toward Functional Analysis of Rickettsial Genomes
  Annals of the New York Academy of Sciences. Dec, 2005  |   Pubmed ID: 16481497
• Identification and Structural Characterization of an Unusual Mycobacterial Monomeromycolyl-diacylglycerol
  Molecular Microbiology. Aug, 2005  |   Pubmed ID: 16091048
• The Intracellular Fate of Salmonella Depends on the Recruitment of Kinesin
  Science (New York, N.Y.). May, 2005  |   Pubmed ID: 15905402
• Antimicrobial Activity of Myotoxic Phospholipases A2 from Crotalid Snake Venoms and Synthetic Peptide Variants Derived from Their C-terminal Region
  Toxicon : Official Journal of the International Society on Toxinology. Jun, 2005  |   Pubmed ID: 15904676
• Cyclic Beta-1,2-glucan is a Brucella Virulence Factor Required for Intracellular Survival
  Nature Immunology. Jun, 2005  |   Pubmed ID: 15880113
• Proteome Analysis of Rickettsia Conorii by Two-dimensional Gel Electrophoresis Coupled with Mass Spectrometry
  FEMS Microbiology Letters. Apr, 2005  |   Pubmed ID: 15837377
• Bactericidal and Antiendotoxic Properties of Short Cationic Peptides Derived from a Snake Venom Lys49 Phospholipase A2
  Antimicrobial Agents and Chemotherapy. Apr, 2005  |   Pubmed ID: 15793109
• Intracellular Trafficking of Parachlamydia Acanthamoebae
  Cellular Microbiology. Apr, 2005  |   Pubmed ID: 15760458
• Brucella Lipopolysaccharide Acts As a Virulence Factor
  Current Opinion in Microbiology. Feb, 2005  |   Pubmed ID: 15694858
• Bacteria Spurned by Self-absorbed Cells
  Nature Medicine. Jan, 2005  |   Pubmed ID: 15635436
• Brucella Coopts the Small GTPase Sar1 for Intracellular Replication
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005  |   Pubmed ID: 15632218
• Link Between Impaired Maturation of Phagosomes and Defective Coxiella Burnetii Killing in Patients with Chronic Q Fever
  The Journal of Infectious Diseases. Nov, 2004  |   Pubmed ID: 15499532
• Macropinocytosis of Polyplexes and Recycling of Plasmid Via the Clathrin-dependent Pathway Impair the Transfection Efficiency of Human Hepatocarcinoma Cells
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2004  |   Pubmed ID: 15294184
• Improved Methods for Producing Outer Membrane Vesicles in Gram-negative Bacteria
  Research in Microbiology. Jul-Aug, 2004  |   Pubmed ID: 15249060
• Intracellular Trafficking Study of a RB51 B. Abortus Vaccinal Strain Isolated from Cow Milk
  Veterinary Microbiology. Mar, 2004  |   Pubmed ID: 15036539
• Organelle Robbery: Brucella Interactions with the Endoplasmic Reticulum
  Current Opinion in Microbiology. Feb, 2004  |   Pubmed ID: 15036147
• Brucella Evades Macrophage Killing Via VirB-dependent Sustained Interactions with the Endoplasmic Reticulum
  The Journal of Experimental Medicine. Aug, 2003  |   Pubmed ID: 12925673
• 人类的机会主义病原细菌由体内筛选标识的毒力因子。
  The EMBO Journal. Apr, 2003  |   Pubmed ID: 12660152
• Salmonella Typhimurium SifA Effector Protein Requires Its Membrane-anchoring C-terminal Hexapeptide for Its Biological Function
  The Journal of Biological Chemistry. Apr, 2003  |   Pubmed ID: 12574170
• Brucella Intracellular Life: from Invasion to Intracellular Replication
  Veterinary Microbiology. Dec, 2002  |   Pubmed ID: 12414149
• Coxiella Burnetii Survival in THP-1 Monocytes Involves the Impairment of Phagosome Maturation: IFN-gamma Mediates Its Restoration and Bacterial Killing
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002  |   Pubmed ID: 12370385
• Activation of Rho and Rab GTPases Dissociates Brucella Abortus Internalization from Intracellular Trafficking
  Cellular Microbiology. Oct, 2002  |   Pubmed ID: 12366403
• The Cytoplasmic Tail of Invariant Chain Regulates Endosome Fusion and Morphology
  Molecular Biology of the Cell. Jun, 2002  |   Pubmed ID: 12058053
• Survival of Tropheryma Whipplei, the Agent of Whipple's Disease, Requires Phagosome Acidification
  Infection and Immunity. Mar, 2002  |   Pubmed ID: 11854238