Luke C. Davies Systems Immunity Research Institute, Division of Infection and Immunity Cardiff University Biography Publications Institution JoVE Articles Luke C. Davies has not added a biography. If you are Luke C. Davies and would like to personalize this page please email our Author Liaison for assistance. Publications Immune and Metabolic Markers for Identifying and Investigating Severe Coronavirus Disease and Sepsis in Children and Young People (pSeP/COVID ChYP Study): Protocol for a Prospective Cohort Study BMJ Open. Mar, 2023 | Pubmed ID: 36972964 Immune-metabolic Adaptations in Pregnancy: A Potential Stepping-stone to Sepsis EBioMedicine. Dec, 2022 | Pubmed ID: 36470829 MSep: Investigating Physiological and Immune-metabolic Biomarkers in Septic and Healthy Pregnant Women to Predict Feto-maternal Immune Health - a Prospective Observational Cohort Study Protocol BMJ Open. Sep, 2022 | Pubmed ID: 36115679 Oxylipin Metabolism is Controlled by Mitochondrial β-oxidation During Bacterial Inflammation Nature Communications. Jan, 2022 | Pubmed ID: 35013270 NSeP: Immune and Metabolic Biomarkers for Early Detection of Neonatal Sepsis-protocol for a Prospective Multicohort Study BMJ Open. Dec, 2021 | Pubmed ID: 37010923 Innate Immunology in COVID-19-a Living Review. Part II: Dysregulated Inflammation Drives Immunopathology Oxford Open Immunology. 2020 | Pubmed ID: 34192268 Innate Immunology in COVID-19-a Living Review. Part I: Viral Entry, Sensing and Evasion Oxford Open Immunology. 2020 | Pubmed ID: 34192267 Nitric Oxide Orchestrates Metabolic Rewiring in M1 Macrophages by Targeting Aconitase 2 and Pyruvate Dehydrogenase Nature Communications. Feb, 2020 | Pubmed ID: 32019928 The Protective Effect of Inflammatory Monocytes During Systemic C. Albicans Infection is Dependent on Collaboration Between C-type Lectin-like Receptors PLoS Pathogens. Jun, 2019 | Pubmed ID: 31242262 Diversity and Environmental Adaptation of Phagocytic Cell Metabolism Journal of Leukocyte Biology. Jan, 2019 | Pubmed ID: 30247792 Tumour-elicited Neutrophils Engage Mitochondrial Metabolism to Circumvent Nutrient Limitations and Maintain Immune Suppression Nature Communications. Nov, 2018 | Pubmed ID: 30504842 Itaconic Acid Mediates Crosstalk Between Macrophage Metabolism and Peritoneal Tumors The Journal of Clinical Investigation. Aug, 2018 | Pubmed ID: 29920191 Peritoneal Tissue-resident Macrophages Are Metabolically Poised to Engage Microbes Using Tissue-niche Fuels Nature Communications. Dec, 2017 | Pubmed ID: 29234000 Autocrine IL-10 Functions As a Rheostat for M1 Macrophage Glycolytic Commitment by Tuning Nitric Oxide Production Redox Biology. Dec, 2016 | Pubmed ID: 27676159 IL-10 Differentially Controls the Infiltration of Inflammatory Macrophages and Antigen-presenting Cells During Inflammation European Journal of Immunology. Sep, 2016 | Pubmed ID: 27378515 The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal Science (New York, N.Y.). May, 2014 | Pubmed ID: 24762537 MiR-192 Induces G2/M Growth Arrest in Aristolochic Acid Nephropathy The American Journal of Pathology. Apr, 2014 | Pubmed ID: 24508230 Tissue-resident Macrophages Nature Immunology. Oct, 2013 | Pubmed ID: 24048120 Distinct Bone Marrow-derived and Tissue-resident Macrophage Lineages Proliferate at Key Stages During Inflammation Nature Communications. 2013 | Pubmed ID: 23695680 Macrophage Heterogeneity and Acute Inflammation European Journal of Immunology. Sep, 2011 | Pubmed ID: 21952806 A Quantifiable Proliferative Burst of Tissue Macrophages Restores Homeostatic Macrophage Populations After Acute Inflammation European Journal of Immunology. Aug, 2011 | Pubmed ID: 21710478 Hoxb8 Conditionally Immortalised Macrophage Lines Model Inflammatory Monocytic Cells with Important Similarity to Dendritic Cells European Journal of Immunology. Feb, 2011 | Pubmed ID: 21268006 Tissue-resident Macrophages Actively Suppress IL-1beta Release Via a Reactive Prostanoid/IL-10 Pathway The EMBO Journal. | Pubmed ID: 32484988 Effective Gene Modification in Mouse Tissue-Resident Peritoneal Macrophages by Intraperitoneal Delivery of Lentiviral Vectors Molecular Therapy. Methods & Clinical Development. | Pubmed ID: 31720306 Author Spotlight: Exploring Macrophage Immunometabolism Through Lentiviral Vector-Mediated Gene Manipulation Mark Gurney1, Luke C. Davies1,2, Ruth E. Jones1, Valentina M. Bart1, Robert H. Jenkins1, Paul Brennan1, Philip R. Taylor1,3, Magdalena A. Czubala1 1Systems Immunity Research Institute, Division of Infection and Immunity, Cardiff University, 2Biomedical Sciences Unit, Faculty of Medicine, Health and Life Science, Swansea University, 3UK Dementia Research Institute JoVE 64926 Imunologia e Infecção
Author Spotlight: Exploring Macrophage Immunometabolism Through Lentiviral Vector-Mediated Gene Manipulation Mark Gurney1, Luke C. Davies1,2, Ruth E. Jones1, Valentina M. Bart1, Robert H. Jenkins1, Paul Brennan1, Philip R. Taylor1,3, Magdalena A. Czubala1 1Systems Immunity Research Institute, Division of Infection and Immunity, Cardiff University, 2Biomedical Sciences Unit, Faculty of Medicine, Health and Life Science, Swansea University, 3UK Dementia Research Institute JoVE 64926 Imunologia e Infecção