Oleh Pochynyuk Department of Integrative Biology & Pharmacology University of Texas Health Science Center at Houston Biography Publications Institution JoVE Articles Oleh Pochynyuk has not added a biography. If you are Oleh Pochynyuk and would like to personalize this page please email our Author Liaison for assistance. Publications Control of ENaC-mediated Sodium Reabsorption in the Distal Nephron by Bradykinin Vitamins and Hormones. 2015 | Pubmed ID: 25817868 IGF-1 and Insulin Exert Opposite Actions on ClC-K2 Activity in the Cortical Collecting Ducts American Journal of Physiology. Renal Physiology. Jan, 2015 | Pubmed ID: 25339702 Emerging Role of the Calcium-activated, Small Conductance, SK3 K+ Channel in Distal Tubule Function: Regulation by TRPV4 PloS One. 2014 | Pubmed ID: 24762817 Direct Regulation of ENaC by Bradykinin in the Distal Nephron. Implications for Renal Sodium Handling Current Opinion in Nephrology and Hypertension. Mar, 2014 | Pubmed ID: 24378775 Chronic Angiotensin II Infusion Drives Extensive Aldosterone-independent Epithelial Na+ Channel Activation Hypertension. Dec, 2013 | Pubmed ID: 24060890 Direct Inhibition of Basolateral Kir4.1/5.1 and Kir4.1 Channels in the Cortical Collecting Duct by Dopamine American Journal of Physiology. Renal Physiology. Nov, 2013 | Pubmed ID: 23986512 Discrete Control of TRPV4 Channel Function in the Distal Nephron by Protein Kinases A and C The Journal of Biological Chemistry. Jul, 2013 | Pubmed ID: 23709216 Ca2+ Imaging As a Tool to Assess TRP Channel Function in Murine Distal Nephrons Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23529445 Recording Ion Channels in Isolated, Split-opened Tubules Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23529443 Primary Aldosteronism and Impaired Natriuresis in Mice Underexpressing TGFβ1 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23503843 TRPV4 Dysfunction Promotes Renal Cystogenesis in Autosomal Recessive Polycystic Kidney Disease Journal of the American Society of Nephrology : JASN. Mar, 2013 | Pubmed ID: 23411787 Novel Insights into TRPV4 Function in the Kidney Pflügers Archiv : European Journal of Physiology. Feb, 2013 | Pubmed ID: 23207579 Direct Activation of ENaC by Angiotensin II: Recent Advances and New Insights Current Hypertension Reports. Feb, 2013 | Pubmed ID: 23180052 Salt-dependent Inhibition of Epithelial Na+ Channel-mediated Sodium Reabsorption in the Aldosterone-sensitive Distal Nephron by Bradykinin Hypertension. Nov, 2012 | Pubmed ID: 23033373 Function of Transient Receptor Potential Cation Channel Subfamily V Member 4 (TRPV4) As a Mechanical Transducer in Flow-sensitive Segments of Renal Collecting Duct System The Journal of Biological Chemistry. Mar, 2012 | Pubmed ID: 22298783 Angiotensin II Increases Activity of the Epithelial Na+ Channel (ENaC) in Distal Nephron Additively to Aldosterone The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22086923 Role of Collecting Duct AT1a Receptors in Concentrating Urine Journal of the American Society of Nephrology : JASN. Dec, 2011 | Pubmed ID: 22034643 Purinergic Activation of Ca2+-permeable TRPV4 Channels is Essential for Mechano-sensitivity in the Aldosterone-sensitive Distal Nephron PloS One. 2011 | Pubmed ID: 21850238 Af17 Deficiency Increases Sodium Excretion and Decreases Blood Pressure Journal of the American Society of Nephrology : JASN. Jun, 2011 | Pubmed ID: 21546577 Voltage-dependent Gating Underlies Loss of ENaC Function in Pseudohypoaldosteronism Type 1 Biophysical Journal. Apr, 2011 | Pubmed ID: 21504729 Bradykinin Acutely Inhibits Activity of the Epithelial Na+ Channel in Mammalian Aldosterone-sensitive Distal Nephron American Journal of Physiology. Renal Physiology. May, 2011 | Pubmed ID: 21325499 Acute Cholesterol-induced Anti-natriuretic Effects: Role of Epithelial Na+ Channel Activity, Protein Levels, and Processing The Journal of Biological Chemistry. Jan, 2011 | Pubmed ID: 21041305 Purinergic Inhibition of ENaC Produces Aldosterone Escape Journal of the American Society of Nephrology : JASN. Nov, 2010 | Pubmed ID: 20813869 Endothelin-1 Inhibits the Epithelial Na+ Channel Through BetaPix/14-3-3/Nedd4-2 Journal of the American Society of Nephrology : JASN. May, 2010 | Pubmed ID: 20338996 Dietary Na+ Inhibits the Open Probability of the Epithelial Sodium Channel in the Kidney by Enhancing Apical P2Y2-receptor Tone FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2010 | Pubmed ID: 20097874 Activation of the Epithelial Na+ Channel in the Collecting Duct by Vasopressin Contributes to Water Reabsorption American Journal of Physiology. Renal Physiology. Nov, 2009 | Pubmed ID: 19692483 Intrinsic Voltage Dependence of the Epithelial Na+ Channel is Masked by a Conserved Transmembrane Domain Tryptophan The Journal of Biological Chemistry. Sep, 2009 | Pubmed ID: 19620245 Thiazolidinedione-induced Fluid Retention is Independent of Collecting Duct AlphaENaC Activity Journal of the American Society of Nephrology : JASN. Apr, 2009 | Pubmed ID: 19158355 Paracrine Regulation of the Epithelial Na+ Channel in the Mammalian Collecting Duct by Purinergic P2Y2 Receptor Tone The Journal of Biological Chemistry. Dec, 2008 | Pubmed ID: 18981175 Physiologic Regulation of the Epithelial Sodium Channel by Phosphatidylinositides Current Opinion in Nephrology and Hypertension. Sep, 2008 | Pubmed ID: 18695396 Regulation of the Epithelial Na+ Channel by Endothelin-1 in Rat Collecting Duct American Journal of Physiology. Renal Physiology. Oct, 2008 | Pubmed ID: 18667482 Insight Toward Epithelial Na+ Channel Mechanism Revealed by the Acid-sensing Ion Channel 1 Structure IUBMB Life. Sep, 2008 | Pubmed ID: 18459164 Purinergic Control of Apical Plasma Membrane PI(4,5)P2 Levels Sets ENaC Activity in Principal Cells American Journal of Physiology. Renal Physiology. Jan, 2008 | Pubmed ID: 17913833 Ion Channel Regulation by Ras, Rho, and Rab Small GTPases Experimental Biology and Medicine (Maywood, N.J.). Nov, 2007 | Pubmed ID: 17959838 Molecular Determinants of PI(4,5)P2 and PI(3,4,5)P3 Regulation of the Epithelial Na+ Channel The Journal of General Physiology. Oct, 2007 | Pubmed ID: 17893193 Acute Regulation of the Epithelial Na+ Channel by Phosphatidylinositide 3-OH Kinase Signaling in Native Collecting Duct Principal Cells Journal of the American Society of Nephrology : JASN. Jun, 2007 | Pubmed ID: 17442787 Quantifying RhoA Facilitated Trafficking of the Epithelial Na+ Channel Toward the Plasma Membrane with Total Internal Reflection Fluorescence-fluorescence Recovery After Photobleaching The Journal of Biological Chemistry. May, 2007 | Pubmed ID: 17376773 Binding and Direct Activation of the Epithelial Na+ Channel (ENaC) by Phosphatidylinositides The Journal of Physiology. Apr, 2007 | Pubmed ID: 17272344 Functional Reconstitution of the Human Epithelial Na+ Channel in a Mammalian Expression System Methods in Molecular Biology (Clifton, N.J.). 2006 | Pubmed ID: 16929934 Rapid Translocation and Insertion of the Epithelial Na+ Channel in Response to RhoA Signaling The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16829523 Regulation of the Epithelial Na+ Channel (ENaC) by Phosphatidylinositides American Journal of Physiology. Renal Physiology. May, 2006 | Pubmed ID: 16601296 Regulation of Epithelial Na+ Channel Activity by Conserved Serine/threonine Switches Within Sorting Signals The Journal of Biological Chemistry. Nov, 2005 | Pubmed ID: 16203727 Identification of a Functional Phosphatidylinositol 3,4,5-trisphosphate Binding Site in the Epithelial Na+ Channel The Journal of Biological Chemistry. Nov, 2005 | Pubmed ID: 16154997 Ras Couples Phosphoinositide 3-OH Kinase to the Epithelial Na+ Channel Biochimica Et Biophysica Acta. May, 2005 | Pubmed ID: 15893513 Implementieren der Patch-Clamp und Live-Fluoreszenzmikroskopie, um funktionelle Eigenschaften von frisch isolierten PKD Epithel-Monitor Tengis S. Pavlov1, Daria V. Ilatovskaya1, Oleg Palygin1, Vladislav Levchenko1, Oleh Pochynyuk2, Alexander Staruschenko1 1Department of Physiology, Medical College of Wisconsin, 2Department of Integrative Biology & Pharmacology, University of Texas Health Science Center at Houston JoVE 53035 Biologia
Implementieren der Patch-Clamp und Live-Fluoreszenzmikroskopie, um funktionelle Eigenschaften von frisch isolierten PKD Epithel-Monitor Tengis S. Pavlov1, Daria V. Ilatovskaya1, Oleg Palygin1, Vladislav Levchenko1, Oleh Pochynyuk2, Alexander Staruschenko1 1Department of Physiology, Medical College of Wisconsin, 2Department of Integrative Biology & Pharmacology, University of Texas Health Science Center at Houston JoVE 53035 Biologia