Shin Aoki Faculty of Pharmaceutical Sciences Tokyo University of Science Biography Publications Institution JoVE Articles Shin Aoki has not added a biography. If you are Shin Aoki and would like to personalize this page please email our Author Liaison for assistance. Publications Stereospecific Synthesis of Tris-heteroleptic Tris-cyclometalated Iridium(III) Complexes Via Different Heteroleptic Halogen-Bridged Iridium(III) Dimers and Their Photophysical Properties Inorganic Chemistry. Apr, 2018 | Pubmed ID: 29611703 Increased Diversity with Reduced "diversity Evenness" of Tumor Infiltrating T-cells for the Successful Cancer Immunotherapy Scientific Reports. Jan, 2018 | Pubmed ID: 29348598 Size-Based Differentiation of Cancer and Normal Cells by a Particle Size Analyzer Assisted by a Cell-Recognition PC Software Biological & Pharmaceutical Bulletin. Apr, 2018 | Pubmed ID: 29332929 A Chemical Modulator of P53 Transactivation That Acts As a Radioprotective Agonist Molecular Cancer Therapeutics. Feb, 2018 | Pubmed ID: 28939557 Synthesis of Disaccharide Nucleosides Utilizing the Temporary Protection of the 2',3'-cis-Diol of Ribonucleosides by a Boronic Ester Molecules (Basel, Switzerland). Oct, 2017 | Pubmed ID: 28974027 Concise and Versatile Synthesis of Sulfoquinovosyl Acyl Glycerol Derivatives for Biological Applications Chemical & Pharmaceutical Bulletin. 2017 | Pubmed ID: 28566649 Efficient Synthesis of Tris-Heteroleptic Iridium(III) Complexes Based on the Zn-Promoted Degradation of Tris-Cyclometalated Iridium(III) Complexes and Their Photophysical Properties Inorganic Chemistry. Jan, 2017 | Pubmed ID: 28036181 Design and Synthesis of Tris-Heteroleptic Cyclometalated Iridium(III) Complexes Consisting of Three Different Nonsymmetric Ligands Based on Ligand-Selective Electrophilic Reactions Via Interligand HOMO Hopping Phenomena Inorganic Chemistry. Jan, 2017 | Pubmed ID: 28035836 Cationic Amphiphilic Tris-Cyclometalated Iridium(III) Complexes Induce Cancer Cell Death Via Interaction with Ca-Calmodulin Complex Bioconjugate Chemistry. 02, 2017 | Pubmed ID: 28032992 Supramolecular Complexes Formed by the Self-assembly of Hydrophobic Bis(Zn(2+)-cyclen) Complexes, Copper, and Di- or Triimide Units for the Hydrolysis of Phosphate Mono- and Diesters in Two-Phase Solvent Systems (Cyclen=1,4,7,10-Tetraazacyclododecane) Chemical & Pharmaceutical Bulletin. 2016 | Pubmed ID: 27150477 Development of a Novel Sulfonate Ester-based Prodrug Strategy Bioorganic & Medicinal Chemistry Letters. Jan, 2016 | Pubmed ID: 26642767 Enrichment of Circulating Tumor Cells in Tumor-bearing Mouse Blood by a Deterministic Lateral Displacement Microfluidic Device Biomedical Microdevices. 2015 | Pubmed ID: 26002773 Photochemical Properties of Red-Emitting Tris(cyclometalated) Iridium(III) Complexes Having Basic and Nitro Groups and Application to PH Sensing and Photoinduced Cell Death Inorganic Chemistry. Jun, 2015 | Pubmed ID: 25978770 Design and Synthesis of Amphiphilic and Luminescent Tris-Cyclometalated Iridium(III) Complexes Containing Cationic Peptides As Inducers and Detectors of Cell Death Via a Calcium-Dependent Pathway Bioconjugate Chemistry. May, 2015 | Pubmed ID: 25875312 Synthesis of Disaccharide Nucleosides by the O-glycosylation of Natural Nucleosides with Thioglycoside Donors Chemistry, an Asian Journal. Mar, 2015 | Pubmed ID: 25677492 Supramolecular Phosphatases Formed by the Self-assembly of the Bis(Zn²⁺-cyclen) Complex, Copper(II), and Barbital Derivatives in Water Chemistry, an Asian Journal. Oct, 2014 | Pubmed ID: 25080369 AS-2, a Novel Inhibitor of P53-dependent Apoptosis, Prevents Apoptotic Mitochondrial Dysfunction in a Transcription-independent Manner and Protects Mice from a Lethal Dose of Ionizing Radiation Biochemical and Biophysical Research Communications. Aug, 2014 | Pubmed ID: 25026551 Design and Synthesis of 8-hydroxyquinoline-based Radioprotective Agents Bioorganic & Medicinal Chemistry. Aug, 2014 | Pubmed ID: 25002230 Design, Synthesis and Photochemical Reactivation of Caged Prodrugs of 8-hydroxyquinoline-based Enzyme Inhibitors Chemical & Pharmaceutical Bulletin. 2014 | Pubmed ID: 24990501 Design and Synthesis of Chiral Zn2+ Complexes Mimicking Natural Aldolases for Catalytic C-C Bond Forming Reactions in Aqueous Solution International Journal of Molecular Sciences. Jan, 2014 | Pubmed ID: 24481060 Synthesis and Photochemical Properties of PH Responsive Tris-cyclometalated Iridium(III) Complexes That Contain a Pyridine Ring on the 2-phenylpyridine Ligand Inorganic Chemistry. Jan, 2014 | Pubmed ID: 24341415 Evaluation of Zinc (II) Chelators for Inhibiting P53-mediated Apoptosis Oncotarget. Dec, 2013 | Pubmed ID: 24280450 Design and Synthesis of a Luminescent Cyclometalated Iridium(III) Complex Having N,N-diethylamino Group That Stains Acidic Intracellular Organelles and Induces Cell Death by Photoirradiation Inorganic Chemistry. Dec, 2012 | Pubmed ID: 23145911 Selective Capture and Collection of Live Target Cells Using a Photoreactive Silicon Wafer Device Modified with Antibodies Via a Photocleavable Linker Langmuir : the ACS Journal of Surfaces and Colloids. Sep, 2012 | Pubmed ID: 22889078 Molecular Recognition of Hydrocarbon Guests by a Supramolecular Capsule Formed by the 4:4 Self-assembly of Tris(Zn(2+)-cyclen) and Trithiocyanurate in Aqueous Solution Chemistry, an Asian Journal. May, 2012 | Pubmed ID: 22311622 Potent Inhibition of Dinuclear Zinc(II) Peptidase, an Aminopeptidase from Aeromonas Proteolytica, by 8-quinolinol Derivatives: Inhibitor Design Based on Zn2+ Fluorophores, Kinetic, and X-ray Crystallographic Study Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Apr, 2012 | Pubmed ID: 22311113 One-pot Chemoenzymatic Synthesis of Chiral 1,3-diols Using an Enantioselective Aldol Reaction with Chiral Zn2+ Complex Catalysts and Enzymatic Reduction Using Oxidoreductases with Cofactor Regeneration Chemistry, an Asian Journal. Jan, 2012 | Pubmed ID: 22174123 Photochemical Cleavage Reaction of 8-quinolinyl Sulfonates That Are Halogenated and Nitrated at the 7-position Chemical & Pharmaceutical Bulletin. 2011 | Pubmed ID: 22041071 11B NMR Sensing of D-block Metal Ions in Vitro and in Cells Based on the Carbon-boron Bond Cleavage of Phenylboronic Acid-pendant Cyclen (cyclen = 1,4,7,10-tetraazacyclododecane) Inorganic Chemistry. Nov, 2011 | Pubmed ID: 22010826 Selective Hydrolysis of Phosphate Monoester by a Supramolecular Phosphatase Formed by the Self-assembly of a Bis(Zn(2+)-cyclen) Complex, Cyanuric Acid, and Copper in an Aqueous Solution (cyclen = 1,4,7,10-tetraazacyclododecane) Inorganic Chemistry. Oct, 2011 | Pubmed ID: 21936489 Regioselective Aromatic Substitution Reactions of Cyclometalated Ir(III) Complexes: Synthesis and Photochemical Properties of Substituted Ir(III) Complexes That Exhibit Blue, Green, and Red Color Luminescence Emission Inorganic Chemistry. Feb, 2011 | Pubmed ID: 21214169 Molecular Recognition of Inositol 1,4,5-trisphosphate and Model Compounds in Aqueous Solution by Ditopic Zn(2+) Complexes Containing Chiral Linkers Inorganic Chemistry. Jun, 2010 | Pubmed ID: 20420391 Sodium Orthovanadate Inhibits P53-mediated Apoptosis Cancer Research. Jan, 2010 | Pubmed ID: 20048077 Design and Synthesis of a Fluorescent Probe for Zn2+, 5,7-bis(N,N-dimethylaminosulfonyl)-8-hydroxyquinoline-pendant 1,4,7,10-tetraazacyclododecane and Zn2+-dependent Hydrolytic and Zn2+-independent Photochemical Reactivation of Its Benzenesulfonyl-caged Derivative Inorganic Chemistry. Feb, 2010 | Pubmed ID: 20039701 Photochemical Cleavage Reactions of 8-quinolinyl Sulfonates in Aqueous Solution Chemical & Pharmaceutical Bulletin. Nov, 2009 | Pubmed ID: 19881278 Chiral Catalysts Dually Functionalized with Amino Acid and Zn2+ Complex Components for Enantioselective Direct Aldol Reactions Inspired by Natural Aldolases: Design, Synthesis, Complexation Properties, Catalytic Activities, and Mechanistic Study Chemistry (Weinheim an Der Bergstrasse, Germany). Oct, 2009 | Pubmed ID: 19746465 Design and Synthesis of a Stable Supramolecular Trigonal Prism Formed by the Self-assembly of a Linear Tetrakis(Zn2+-cyclen) Complex and Trianionic Trithiocyanuric Acid in Aqueous Solution and Its Complexation with DNA (cyclen = 1,4,7,10-tetraazacyclododecane) Inorganic Chemistry. Oct, 2009 | Pubmed ID: 19743814 Design and Synthesis of a Photocleavable Biotin-linker for the Photoisolation of Ligand-receptor Complexes Based on the Photolysis of 8-quinolinyl Sulfonates in Aqueous Solution Bioorganic & Medicinal Chemistry. May, 2009 | Pubmed ID: 19362845 Photolysis of the Sulfonamide Bond of Metal Complexes of N-dansyl-1,4,7,10-tetraazacyclododecane in Aqueous Solution: a Mechanistic Study and Application to the Photorepair of Cis,syn-cyclobutane Thymine Photodimer Chemistry, an Asian Journal. Apr, 2009 | Pubmed ID: 19165842 BODIPY-based Fluorescent Redox Potential Sensors That Utilize Reversible Redox Properties of Flavin Chembiochem : a European Journal of Chemical Biology. Apr, 2008 | Pubmed ID: 18338353 Design and Synthesis of a Caged Zn2+ Probe, 8-benzenesulfonyloxy-5-N,N-dimethylaminosulfonylquinolin-2-ylmethyl-pendant 1,4,7,10-tetraazacyclododecane, and Its Hydrolytic Uncaging Upon Complexation with Zn2+ Inorganic Chemistry. Apr, 2008 | Pubmed ID: 18321042 A New Fluorescent Probe for Zinc(II): an 8-hydroxy-5-N,N-dimethylaminosulfonylquinoline-pendant 1,4,7,10-tetraazacyclododecane Chemistry (Weinheim an Der Bergstrasse, Germany). Dec, 2006 | Pubmed ID: 16953498 Efficient Cycloreversion of Cis,syn-thymine Photodimer by a Zn2+ -1,4,7,10-tetraazacyclododecane Complex Bearing a Lumiflavin and Tryptophan by Chemical Reduction and Photoreduction of a Lumiflavin Unit Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Nov, 2006 | Pubmed ID: 16944231 A Luminescence Sensor of Inositol 1,4,5-triphosphate and Its Model Compound by Ruthenium-templated Assembly of a Bis(Zn2+-cyclen) Complex Having a 2,2'-bipyridyl Linker (cyclen = 1,4,7,10-tetraazacyclododecane) Journal of the American Chemical Society. Jun, 2005 | Pubmed ID: 15969591 Metal Chelation-controlled Twisted Intramolecular Charge Transfer and Its Application to Fluorescent Sensing of Metal Ions and Anions Journal of the American Chemical Society. Oct, 2004 | Pubmed ID: 15479094 Zinc-nucleic Acid Interaction Chemical Reviews. Feb, 2004 | Pubmed ID: 14871140 Региоселективный O- гликозилирования нуклеозидов через временные 2', 3'-диол защиты борных эфира для синтеза нуклеозидов дисахарида Hidehisa Someya1, Taiki Itoh1, Mebae Kato1, Shin Aoki1,2 1Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2Imaging Frontier Center, Tokyo University of Science JoVE 57897 Química
Региоселективный O- гликозилирования нуклеозидов через временные 2', 3'-диол защиты борных эфира для синтеза нуклеозидов дисахарида Hidehisa Someya1, Taiki Itoh1, Mebae Kato1, Shin Aoki1,2 1Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2Imaging Frontier Center, Tokyo University of Science JoVE 57897 Química