Young Kee Shin Research Institute of Pharmaceutical Science, Department of Pharmacy, College of Pharmacy Seoul National University Biography Publications Institution JoVE Articles Young Kee Shin has not added a biography. If you are Young Kee Shin and would like to personalize this page please email our Author Liaison for assistance. Publications Human Papillomavirus: Current and Future RNAi Therapeutic Strategies for Cervical Cancer Journal of Clinical Medicine. 2015 | Pubmed ID: 26239469 Basal Buffer Systems for a Newly Glycosylated Recombinant Human Interferon-β with Biophysical Stability and DoE Approaches European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Oct, 2015 | Pubmed ID: 26215462 Anoctamin 1 (TMEM16A) is Essential for Testosterone-induced Prostate Hyperplasia Proceedings of the National Academy of Sciences of the United States of America. Aug, 2015 | Pubmed ID: 26153424 Human Papillomavirus E6/E7-Specific SiRNA Potentiates the Effect of Radiotherapy for Cervical Cancer in Vitro and in Vivo International Journal of Molecular Sciences. 2015 | Pubmed ID: 26035754 Development of an Advanced Synthetic Route to Macrosphelides and Its Application to the Discovery of a More Potent Macrosphelide Derivative Molecules (Basel, Switzerland). 2014 | Pubmed ID: 25268715 Molecular Function and Regulation of Long Non-coding RNAs: Paradigms with Potential Roles in Cancer Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. Nov, 2014 | Pubmed ID: 25266799 Design and Synthesis of a Macrosphelide A-biotin Chimera Organic & Biomolecular Chemistry. Sep, 2014 | Pubmed ID: 25098405 SMAD4 Suppresses AURKA-induced Metastatic Phenotypes Via Degradation of AURKA in a TGFβ-independent Manner Molecular Cancer Research : MCR. Dec, 2014 | Pubmed ID: 25061104 Glycoengineering of Interferon-β 1a Improves Its Biophysical and Pharmacokinetic Properties PloS One. 2014 | Pubmed ID: 24858932 MET is a Potential Target for Use in Combination Therapy with EGFR Inhibition in Triple-negative/basal-like Breast Cancer International Journal of Cancer. Journal International Du Cancer. May, 2014 | Pubmed ID: 24615768 Overexpression of Cancer-Associated Genes Via Epigenetic Derepression Mechanisms in Gynecologic Cancer Frontiers in Oncology. 2014 | Pubmed ID: 24551595 High Level of CDK4 Amplification is a Poor Prognostic Factor in Well-differentiated and Dedifferentiated Liposarcoma Histology and Histopathology. Jan, 2014 | Pubmed ID: 23852861 Long Non-coding RNAs in Hematologic Malignancies: Road to Translational Research Frontiers in Genetics. 2013 | Pubmed ID: 24312125 Synthesis and Biological Evaluation of a Polyyne-containing Sphingoid Base Probe As a Chemical Tool Bioconjugate Chemistry. Aug, 2013 | Pubmed ID: 23926922 Prognostic Significance of CD151 Overexpression in Non-small Cell Lung Cancer Lung Cancer (Amsterdam, Netherlands). Jul, 2013 | Pubmed ID: 23570797 Regulation of Ovarian Cancer Stem Cells or Tumor-initiating Cells International Journal of Molecular Sciences. 2013 | Pubmed ID: 23528891 Low SP1 Expression Differentially Affects Intestinal-type Compared with Diffuse-type Gastric Adenocarcinoma PloS One. 2013 | Pubmed ID: 23437057 CD24⁺ Ovary Cancer Cells Exhibit an Invasive Mesenchymal Phenotype Biochemical and Biophysical Research Communications. Mar, 2013 | Pubmed ID: 23396061 Tob1 Induces Apoptosis and Inhibits Proliferation, Migration and Invasion of Gastric Cancer Cells by Activating Smad4 and Inhibiting β‑catenin Signaling International Journal of Oncology. Sep, 2012 | Pubmed ID: 22710759 High MET Copy Number and MET Overexpression: Poor Outcome in Non-small Cell Lung Cancer Patients Histology and Histopathology. Feb, 2012 | Pubmed ID: 22207554 A Prognostic Model for Lymph Node-negative Breast Cancer Patients Based on the Integration of Proliferation and Immunity Breast Cancer Research and Treatment. Apr, 2012 | Pubmed ID: 21667120 The Synergistic Therapeutic Effect of Cisplatin with Human Papillomavirus E6/E7 Short Interfering RNA on Cervical Cancer Cell Lines in Vitro and in Vivo International Journal of Cancer. Journal International Du Cancer. Apr, 2012 | Pubmed ID: 21630254 Claudin-4 Overexpression is Associated with Epigenetic Derepression in Gastric Carcinoma Laboratory Investigation; a Journal of Technical Methods and Pathology. Nov, 2011 | Pubmed ID: 21844869 Epigenetic Regulation of Cancer-associated Genes in Ovarian Cancer International Journal of Molecular Sciences. 2011 | Pubmed ID: 21541038 Cancer-associated Splicing Variant of Tumor Suppressor AIMP2/p38: Pathological Implication in Tumorigenesis PLoS Genetics. Mar, 2011 | Pubmed ID: 21483803 The Potential RNAi-based Combination Therapeutics Archives of Pharmacal Research. Jan, 2011 | Pubmed ID: 21468909 Triple-negative, Basal-like, and Quintuple-negative Breast Cancers: Better Prediction Model for Survival BMC Cancer. 2010 | Pubmed ID: 20860845 The Transcription Factor MIST1 is a Novel Human Gastric Chief Cell Marker Whose Expression is Lost in Metaplasia, Dysplasia, and Carcinoma The American Journal of Pathology. Sep, 2010 | Pubmed ID: 20709804 LYN is a Mediator of Epithelial-mesenchymal Transition and a Target of Dasatinib in Breast Cancer Cancer Research. Mar, 2010 | Pubmed ID: 20215510 Merkel Cell Carcinoma: Our Experience with Seven Patients in Korea and a Literature Review Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS. Dec, 2010 | Pubmed ID: 20207211 Derepression of CLDN3 and CLDN4 During Ovarian Tumorigenesis is Associated with Loss of Repressive Histone Modifications Carcinogenesis. Jun, 2010 | Pubmed ID: 20053926 Resveratrol Suppresses Growth of Human Ovarian Cancer Cells in Culture and in a Murine Xenograft Model: Eukaryotic Elongation Factor 1A2 As a Potential Target Cancer Research. Sep, 2009 | Pubmed ID: 19738051 Identification of Novel Reference Genes Using Multiplatform Expression Data and Their Validation for Quantitative Gene Expression Analysis PloS One. 2009 | Pubmed ID: 19584937 Expression of Sonic Hedgehog Signaling Molecules in Normal, Hyperplastic and Carcinomatous Endometrium Pathology International. May, 2009 | Pubmed ID: 19432668 Magnolia Officinalis Reverses Alcoholic Fatty Liver by Inhibiting the Maturation of Sterol Regulatory Element-binding Protein-1c Journal of Pharmacological Sciences. Apr, 2009 | Pubmed ID: 19372631 Honokiol Reverses Alcoholic Fatty Liver by Inhibiting the Maturation of Sterol Regulatory Element Binding Protein-1c and the Expression of Its Downstream Lipogenesis Genes Toxicology and Applied Pharmacology. Apr, 2009 | Pubmed ID: 19371623 A Novel Mutation in the Linker Domain of the Signal Transducer and Activator of Transcription 3 Gene, P.Lys531Glu, in Hyper-IgE Syndrome The Journal of Allergy and Clinical Immunology. Apr, 2009 | Pubmed ID: 19348930 Enhanced CD24 Expression in Endometrial Carcinoma and Its Expression Pattern in Normal and Hyperplastic Endometrium Histology and Histopathology. Mar, 2009 | Pubmed ID: 19130400 Liver X Receptor Mediates Hepatitis B Virus X Protein-induced Lipogenesis in Hepatitis B Virus-associated Hepatocellular Carcinoma Hepatology (Baltimore, Md.). Apr, 2009 | Pubmed ID: 19105208 Inhibitory Effects of Oligonol on Phorbol Ester-induced Tumor Promotion and COX-2 Expression in Mouse Skin: NF-kappaB and C/EBP As Potential Targets Cancer Letters. Jan, 2009 | Pubmed ID: 18848748 Expression of Bmi-1 Protein in Tumor Tissues is Associated with Favorable Prognosis in Breast Cancer Patients Breast Cancer Research and Treatment. Jan, 2009 | Pubmed ID: 18228133 Extensive Alteration in the Expression Profiles of TGFB Pathway Signaling Components and TP53 is Observed Along the Gastric Dysplasia-carcinoma Sequence Histology and Histopathology. Dec, 2008 | Pubmed ID: 18830930 Involvement of Promyelocytic Leukemia Protein in the Ethanol-induced Apoptosis in Mouse Embryo Fibroblasts Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. Jul, 2008 | Pubmed ID: 18591875 Identification of Formaldehyde-responsive Genes by Suppression Subtractive Hybridization Toxicology. Jan, 2008 | Pubmed ID: 18045764 The Clinical Significance of Serum N-terminal Pro-brain Natriuretic Peptide in Systemic Sclerosis Patients Clinical Rheumatology. Apr, 2008 | Pubmed ID: 17899307 Overexpression of Interleukin-10 in Sentinel Lymph Node with Breast Cancer Annals of Surgical Oncology. Nov, 2007 | Pubmed ID: 17762971 Clinical Significance of CD99 Down-regulation in Gastric Adenocarcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2007 | Pubmed ID: 17473187 Overexpression of CD24: Association with Invasiveness in Urothelial Carcinoma of the Bladder Archives of Pathology & Laboratory Medicine. Feb, 2007 | Pubmed ID: 17284113 Inactivation of SMAD4 Tumor Suppressor Gene During Gastric Carcinoma Progression Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2007 | Pubmed ID: 17200344 Resveratrol Modulates Phorbol Ester-induced Pro-inflammatory Signal Transduction Pathways in Mouse Skin in Vivo: NF-kappaB and AP-1 As Prime Targets Biochemical Pharmacology. Nov, 2006 | Pubmed ID: 16999939 Enhanced Expression of Hedgehog Signaling Molecules in Squamous Cell Carcinoma of Uterine Cervix and Its Precursor Lesions Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Aug, 2006 | Pubmed ID: 16778829 Combining Multiple Microarrays in the Presence of Controlling Variables Bioinformatics (Oxford, England). Jul, 2006 | Pubmed ID: 16705015 Increased Expression of Sonic Hedgehog and Altered Methylation of Its Promoter Region in Gastric Cancer and Its Related Lesions Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. May, 2006 | Pubmed ID: 16528374 Resveratrol Inhibits Phorbol Ester-induced Expression of COX-2 and Activation of NF-kappaB in Mouse Skin by Blocking IkappaB Kinase Activity Carcinogenesis. Jul, 2006 | Pubmed ID: 16474181 Aberrant Hypermethylation of RASSF1A Promoter in Ovarian Borderline Tumors and Carcinomas Virchows Archiv : an International Journal of Pathology. Mar, 2006 | Pubmed ID: 16315018 Rapid Divergency of Rodent CD99 Orthologs: Implications for the Evolution of the Pseudoautosomal Region Gene. Jul, 2005 | Pubmed ID: 15978751 HUlip, a Human Homologue of Unc-33-like Phosphoprotein of Caenorhabditis Elegans; Immunohistochemical Localization in the Developing Human Brain and Patterns of Expression in Nervous System Tumors Journal of Neuro-oncology. May, 2005 | Pubmed ID: 15933812 Cytoplasmic CD24 Expression in Advanced Ovarian Serous Borderline Tumors Gynecologic Oncology. May, 2005 | Pubmed ID: 15863133 Human Lysyl-tRNA Synthetase is Secreted to Trigger Proinflammatory Response Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15851690 [6]-Gingerol Inhibits COX-2 Expression by Blocking the Activation of P38 MAP Kinase and NF-kappaB in Phorbol Ester-stimulated Mouse Skin Oncogene. Apr, 2005 | Pubmed ID: 15735738 The Novel Cytokine P43 Stimulates Dermal Fibroblast Proliferation and Wound Repair The American Journal of Pathology. Feb, 2005 | Pubmed ID: 15681823 The Haploinsufficient Tumor Suppressor P18 Upregulates P53 Via Interactions with ATM/ATR Cell. Jan, 2005 | Pubmed ID: 15680327 Solution Structure of the Cytoplasmic Domain of Human CD99 Type I Molecules and Cells. Aug, 2004 | Pubmed ID: 15359120 An Immunohistochemical Study of the Expression of Adhesion Molecules in Gallbladder Lesions The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. May, 2004 | Pubmed ID: 15100237 Targeted Cytotoxic Effect of Anti-JL1 Immunotoxin Against a Human Leukemic Cell Line and Its Clinical Implications Cancer Immunology, Immunotherapy : CII. Aug, 2003 | Pubmed ID: 12768327 Cloning, Genomic Organization, Alternative Transcripts and Expression Analysis of CD99L2, a Novel Paralog of Human CD99, and Identification of Evolutionary Conserved Motifs Gene. Mar, 2003 | Pubmed ID: 12706889 An Improved Protocol of Biotinylated Tyramine-based Immunohistochemistry Minimizing Nonspecific Background Staining The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Jan, 2003 | Pubmed ID: 12502763 The Enhanced Reactivity of Endogenous Biotin-like Molecules by Antigen Retrieval Procedures and Signal Amplification with Tyramine The Histochemical Journal. Mar-Apr, 2002 | Pubmed ID: 12495214 Mutations of the Immunoglobulin Heavy Chain Variable Region Gene in CD99-deficient BJAB Cell Line Molecules and Cells. Apr, 2002 | Pubmed ID: 12018845 डिजिटल बूंद पीसीआर Formalin तय आयल एम्बेडेड निर्देश मानक सेल लाइनों में BRAF V600E उत्परिवर्तन का पता लगाने के लिए रोजगार Nirmal Rajasekaran1, Myung Ryurl Oh3, Sung-Su Kim1, Si Eun Kim3, Young Deug Kim4, Hyun-Jeung Choi2, Bohyun Byun2, Young Kee Shin1,2 1Research Institute of Pharmaceutical Science, Department of Pharmacy, College of Pharmacy, Seoul National University, 2The Center for Anti-Cancer CDx, N-Bio, Seoul National University, 3ABION CRO, 4ABION Inc., R&D Center JoVE 53190 Biologia
डिजिटल बूंद पीसीआर Formalin तय आयल एम्बेडेड निर्देश मानक सेल लाइनों में BRAF V600E उत्परिवर्तन का पता लगाने के लिए रोजगार Nirmal Rajasekaran1, Myung Ryurl Oh3, Sung-Su Kim1, Si Eun Kim3, Young Deug Kim4, Hyun-Jeung Choi2, Bohyun Byun2, Young Kee Shin1,2 1Research Institute of Pharmaceutical Science, Department of Pharmacy, College of Pharmacy, Seoul National University, 2The Center for Anti-Cancer CDx, N-Bio, Seoul National University, 3ABION CRO, 4ABION Inc., R&D Center JoVE 53190 Biologia