4.2
Tamanho Celular
O tamanho das células varia muito entre e dentro dos organismos. Por exemplo, as bactérias mais pequenas têm 0,1 micrómetros (μm) de diâmetro—cerca de…
Cells vary widely in size and shape, and these differences are closely linked to their function and physical constraints
Prokaryotic cells, such as bacteria, usually measure only a few micrometers in diameter. Eukaryotic cells are often larger and vary greatly in size due to structural specializations.
For example, the head of a human sperm cell is about four to five micrometers in length. On the other hand, some neurons have axons that extend up to a meter within the human body.
Such variations in size highlight the vital relationship between a cell's surface area and its volume, which affects the efficiency with which materials move in and out of the cell.
Imagine a cell as a cube. When the length of a side increases, the surface area increases to six times the length squared, while the volume increases by the length cubed.
As cell size increases, the surface area-to-volume ratio decreases.
A higher surface area-to-volume ratio makes it easier for materials to move in and out of the cell.
Bacterial cells are small and have a high surface area-to-volume ratio. This high ratio allows nutrients, gases, and waste products to diffuse efficiently across the cell membrane.
Because large cells have a low surface area-to-volume ratio, this limits how quickly they can exchange materials relative to their needs. This also limits how large a single cell can become. Multicellular organisms overcome this limitation by using many small cells that work together rather than a single large cell.
View the full transcript and gain access to JoVE Core videos
Q1: Why are prokaryotic cells so much smaller than eukaryotic cells?
Prokaryotic cells, such as bacteria, typically measure only a few micrometers in diameter and range between 1-10 micrometers. They remain small because they divide before facing size limitations. Eukaryotic cells are considerably larger, typically ranging from 10-100 micrometers, and possess organelles that facilitate intracellular transport and overcome size constraints that prokaryotic cells cannot manage.
Q2: How does the surface area-to-volume ratio affect cell function?
As a cell increases in size, its volume grows proportionally to the cube of its radius, while surface area grows proportional to the square of its radius. This means larger cells have a lower surface area-to-volume ratio, limiting how quickly they can exchange materials relative to their needs. A higher ratio makes it easier for nutrients, gases, and waste products to diffuse efficiently across the cell membrane.
Q3: Why do large cells need organelles to overcome size limitations?
Large cells have a low surface area-to-volume ratio, which limits how quickly they can exchange materials across their membrane relative to their volume. Larger eukaryotic cells have organelles that facilitate intracellular transport, allowing substances to move efficiently within the cell. This compartmentalization and microenvironments enable large cells to function despite their size constraints.
Q4: How do multicellular organisms solve the problem of cell size limitations?
Multicellular organisms overcome cell size limitations by using many small cells that work together rather than a single large cell. Small cells maintain a high surface area-to-volume ratio, allowing efficient material exchange. This cooperative approach enables organisms to achieve larger overall size while preserving the efficiency of individual cells in nutrient uptake and waste removal.
Q5: What structural adaptations do cells develop to maximize surface area?
Some cells that must exchange large amounts of substances with the environment develop long, thin protrusions to maximize their surface area-to-volume ratio. Plant root hair cells exemplify this adaptation, featuring elongated structures that facilitate water intake and nutrient absorption. These morphological specializations allow cells to increase their effective membrane area without proportionally increasing their volume.
Q6: How do variations in cell size relate to cell function?
Cell size variations are closely linked to function and physical constraints. For example, sperm cell heads measure four to five micrometers for efficient movement, while neuron axons extend up to a meter to transmit signals across the body. These size differences reflect how cells are specialized to perform specific functions within organisms, with dimensions optimized for their particular roles.
Q7: What happens to diffusion rates as cells become larger?
As cells increase in size, the diffusion rate may limit processes within them because substances must travel greater distances across the cytoplasm. Although larger cells have more total volume requiring nutrient delivery, their surface area-to-volume ratio decreases, slowing the rate at which materials can enter relative to cellular needs. This constraint is a fundamental reason why cells cannot grow indefinitely.