Healthy Blood Donors
Healthy Blood Donors - Related Videos
04:43
COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah
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2025
This study assessed COVID-19 seroprevalence in Jeddah, Saudi Arabia, among healthy blood donors across pre-lockdown, during-lockdown, and post-lockdown periods. Of 3,825 samples, 4.5% tested positive for IgG antibodies. Seroprevalence increased significantly post-lockdown, highlighting the role of asymptomatic transmission and the effectiveness of initial restrictions.
11:31
Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
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Cited by 5 •
2013
The cell membrane modification of red blood cells (RBCs) with hyperbranched polyglycerol (HPG) is presented. Modified RBCs were characterized by aqueous two phase partitioning, osmotic fragility and complement mediated lysis. The camouflage of surface proteins and antigens was evaluated using the flow cytometry and Micro Typing System (MTS) blood phenotyping cards.
12:13
Ex Situ Normothermic Machine Perfusion of Donor Livers
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Cited by 21 •
2015
Here we present a protocol describing oxygenated ex situ machine perfusion of donor liver grafts. This article contains a step by step protocol to procure and prepare the liver graft for machine perfusion, prepare the perfusion fluid, prime the perfusion machine and perform oxygenated normothermic machine perfusion of the liver graft.
07:17
Single Port Donor Nephrectomy
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Cited by 5 •
2011
Single port laparoscopic surgery is changing the standard of care in surgical care like nothing since the laparoscopic technique was introduced 20 years ago. We present out technique of single port donor nephrectomy using the Gelpoint device. We have successfully performed this surgery in 100 patients.
08:37
Corneal Donor Tissue Preparation for Endothelial Keratoplasty
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Cited by 31 •
2012
Endothelial corneal transplantation is a surgical technique for treatment of posterior corneal diseases. Mechanical microkeratome dissection to prepare tissue results in thinner, more symmetric grafts with less endothelial cell loss and improved outcomes. Dissections can be performed at the eye bank prior to corneal transplantation surgery.
FAQs
These assessments address different risks. Health-history review and physical screening evaluate clinical eligibility, while laboratory testing examines blood for markers of infectious disease. Using both approaches helps identify concerns that may not be apparent from a donor’s reported history or physical assessment alone. Together, they support safer blood collection and more reliable selection of samples for research.
Infectious-disease markers provide laboratory evidence that can influence whether a donor’s blood is appropriate for transfusion or biomedical research. Their evaluation helps identify samples that could endanger recipients and separates suitable reference material from specimens requiring concern. In infection studies, this screening also helps distinguish baseline samples from those associated with infectious conditions.
Samples from healthy blood donors provide reference blood cells, plasma, and immune factors against which specimens from infected or diseased individuals can be compared. This comparison helps researchers recognize changes associated with immune activation and assess variation among human immune responses. The baseline is therefore important for interpreting whether an observed finding reflects disease-related biology or normal variation.
Assessment begins with a health-history review, followed by physical screening and laboratory testing for markers of infectious disease. These stages provide complementary information about clinical eligibility and potential risks in the collected blood. The resulting evaluation supports decisions about whether the sample is suitable for transfusion, biomedical research, or use as a healthy comparison specimen.
Researchers use these samples when they need a healthy reference for studies of immune activation, pathogen detection, or variation in human immune responses. Comparing donor-derived cells, plasma, or immune factors with material from infected or diseased individuals can clarify disease-associated differences. Such samples also contribute to investigations connected with transfusion safety.
A donor-derived reference establishes the characteristics observed in samples collected from individuals without evidence of conditions that would compromise their use. Researchers can then compare infected or diseased specimens with this reference when evaluating immune factors, blood cells, or plasma. This approach supports more focused interpretation of pathogen detection and immune activation findings.