Psychosis Treatment

Psychosis treatment is the clinical management of symptoms such as hallucinations, delusions, and disorganized thinking, with pharmacology providing a central approach for reducing distress and improving functioning. Antipsychotic medicines primarily modulate dopamine signaling by blocking dopamine D2 receptors; many second-generation agents also affect serotonin 5-HT2A receptors, producing distinct effects on symptoms and adverse-event profiles. In pharmacology, treatment selection considers symptom severity, medical history, interactions, adherence, and the balance between benefits and risks such as movement disorders, sedation, and metabolic changes. Studying these therapies supports individualized care, safer prescribing, relapse prevention, and development of more targeted treatments.

Psychosis Treatment - Related Videos

Research

JoVE Journal - Behavior

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

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Cited by 34 •

2013

Handwriting analysis software significantly improves upon existing instruments measuring movement disorders. Individuals at risk for psychosis and healthy controls completed handwriting tasks to test for dyskinesia. Results suggest that youth at risk for psychosis exhibit dyskinesia and that handwriting analysis could significantly contribute to wider dissemination of early identification...

Education

JoVE Core - Pharmacology

Psychosis: Goals of Pharmacotherapy

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2024

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...

Psychosis and Antipsychotic Drugs: Overview

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2024

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

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2024

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered. Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...

Research

JoVE Journal - Neuroscience
Free Sample

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

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Cited by 3 •

2020

This is a 3T magnetic resonance imaging study aiming to investigate grey matter volume differences between cannabis-induced psychosis patients and non-psychotic chronic cannabis users.

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