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Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans
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Capítulos
- 00:05Título
- 01:11Preparing the Drug Assay Plates
- 02:37Assessing the Lethality and Developmental Delay
- 04:53Assaying Pharyngeal Pumping
- 05:55Assay Results from Clozapine Exposure
- 07:08Conclusion
Approaches for testing the effects of antipsychotic drugs (APDs) in Caenorhabditis elegans are demonstrated. Assays are described for testing drug effects on development and viability and on pharyngeal pumping rate. These methods are also applicable for pharmacogenetic experiments with drug classes other than APDs.
