This article describes a method to generate chimeric embryos that are designed to test the species-specific contributions of neural crest and/or other tissues to craniofacial development.
Fish, J. L., Schneider, R. A. Assessing Species-specific Contributions To Craniofacial Development Using Quail-duck Chimeras. J. Vis. Exp. (87), e51534, doi:10.3791/51534 (2014).