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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Article DOI: 10.3791/56439-v • 12:45 min • December 11th, 2017
December 11th, 2017 •
*1, *1, *2, 2, 3, 1, 1, 1
1Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 2Department of Echocardiography, Shanghai Institute of Medical imaging, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, 3Department of Cardiac surgery, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University
* These authors contributed equally

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The establishment of a chronic asynchronous heart failure (HF) model by rapid pacing combined with left bundle branch ablation is presented. Two-dimensional speckle tracking imaging and aortic velocity time integral are applied to validate this stable HF model with left ventricular asynchrony and the benefits of cardiac resynchronization therapy.

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Cardiac Resynchronization Therapy Asynchronous Heart Failure Model Left Bundle Branch Ablation Rapid Pacing Echocardiographic Parameters Molecular Modifications Biologic Modifications LV Pacing Electrode Implantation Transverse Incision Left Parasternal Line Intercostal Space Left Pleural Cavity Rib Retractor Lateral Pericardium
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