Waiting
Processando Login

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Neuroscience / Double Direct Injection of Blood into the…
JoVE Journal
Neuroscience
Author Produced

É necessário ter uma assinatura JoVE para assistir este

JoVE Journal Neuroscience
Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
Immunostaining of Whole-Mount Retinas with the CLARITY Tissue Clearing Method
Journal (Neuroscience)
Immunostaining of Whole-Mount Retinas with the CLARITY Tissue Clearing Method
Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging
Journal (Neuroscience)
Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging
 

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Article DOI: 10.3791/61322-v • 10:34 min • August 30th, 2020
August 30th, 2020 •
1, 1, 1,2, 1,2, 1
1University of Rouen Normandy, INSERM U1239, DC2N, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France, 2Department of Anesthesiology and Critical Care, Rouen University Hospital, Rouen, France

Capítulos

Resumo
Automatic Translation

We described in this protocol a standardized subarachnoid hemorrhage (SAH) mouse model by a double injection of autologous whole-blood into the cisterna magna. The high degree of standardization of the double-injection procedure represents a middle-to-acute model of SAH with relative safety regarding mortality.

Tags

Double Direct Injection Blood Cisterna Magna Subarachnoid Hemorrhage Protocol Physiology Aneurysm Rupture Extravasation Subarachnoid Space Stroke Cases Mortality Rate Cognitive Sequelae Cerebral Ischemia Vasoconstriction Microscopic Vasospasm Therapeutic Options Pathological Events Animal Models Intercranial Aneurysm
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter