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Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

Article DOI: 10.3791/63083-v • 07:53 min • April 15th, 2022
April 15th, 2022 •
*1, *1, 1, 1, 1, 1,2, 1, 1, 1, 1
1Department of Hematology, Zhongnan Hospital of Wuhan University, 2Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology
* These authors contributed equally

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Here, we present a protocol for improving the success of interphase fluorescence in situ hybridization detection on bone marrow smears from multiple myeloma patients.

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Fluorescence In Situ Hybridization (FISH) Genetic Risk Stratification Multiple Myeloma Clonal Plasma Cells Anti-CD138 Magnetic Beads Cytoplasmic Kappa Or Lambda Light Chain Immunoglobulin CIg FISH Interphase FISH Bone Marrow Smear Complex Processes High Specimen Demands High Experimental Costs Helsinki Declaration Ethics Committee Zhongnan Hospital Of Wuhan University
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