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JoVE Journal Cancer Research
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CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells

Article DOI: 10.3791/64025-v • 12:14 min • June 2nd, 2022
June 2nd, 2022 •
1, 1,2, 1
1Umeå Centre for Molecular Medicine, Umeå University, 2Department of Histology and Embryology, Medical Academy, Lithuanian University of Health Sciences

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The CAM-Delam assay to evaluate the metastatic capacity of cancer cells is relatively fast, easy, and cheap. The method can be used for unraveling the molecular mechanisms regulating metastasis formation and for drug screening. An optimized assay for analyzing human tumor samples could be a clinical method for personalized cancer treatment.

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CAM-Delam Assay Metastatic Properties Delamination Invasion Capacity Cancer Cells Metastatic Aggressiveness Scoring Method Fast And Easy Assessment Cheap Assessment CAM-Delam Assay Steps Visual Demonstration Incubation Process Sterilization Process
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