Teste pré-clínico de drogas em tecidos musculares escaláveis de engenharia 3D
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April 07, 2023
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Este protocolo fornece métodos para gerar tecidos cardíacos e musculares esqueléticos modificados em 3D e descreve seu uso em modalidades de triagem pré-clínica de medicamentos. Os métodos descritos utilizam um sistema de detecção magnética para facilitar a avaliação simultânea de 24 tecidos em paralelo.
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Berry, B. J., Luttrell, S. M., Moerk, C. T., Macadangdang, J., Perez, J., Gray, K., Ghazizadeh, H., Kharoufeh, S., Nelsen, B., Geisse, N. A. Preclinical Drug Testing in Scalable 3D Engineered Muscle Tissues. J. Vis. Exp. (194), e64399, doi:10.3791/64399 (2023).
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