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Developing a Simple and Robust Hepatic Model for Pharmacological and Toxicological Applications (Video) | JoVE

A Physiologically-Relevant All-Human 2D+ Hepatic System for Drug Discovery

Article DOI: 10.3791/65992-v • 01:11 min • October 20th, 2023
October 20th, 2023 •
1, 2, 3, 4, 1, 1
1Institute of Regenerative Medicine, LifeNet Health, 2Biologics Division, LifeNet Health, 3LifeSciences Division, LifeNet Health, 4Research and Development, LifeSciences, LifeNet Health

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全人肝培养系统、药物开发、原代人肝细胞、药理学研究、毒理学研究、体外模型平台、表型稳定性、实验重现性、解冻、铺板、维护、二维培养技术、三维系统、附着、可板性、接种密度、功能性、长期培养、肝细胞集落、肝脏特异性标志物、活力、结构完整性、白蛋白水平、尿素水平、 药理学应用、毒理学应用
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